Microbial pathogenesis and ecology. Patzer. I like systems.
Joined November 2015
- Tweets1.1K
- Following175
- Followers97
- Likes3.4K
bugbomb retweeted
When a crystal is placed near a magnet, its electrons can only have certain amounts of energy. When this phenomenon is graphed, fractal patterns called Cantor sets emerge. quantamagazine.org/ten-marti…
bugbomb retweeted
Already lots of qrts about how the ancients had spreadsheets too but it really needs to be emphasized that their sheets look *exactly* like ours
bugbomb retweeted
🚨🚨New paper out!!!
Come for the first large-scale analysis of plasmid copy number across species,
stay for one of the most intriguing results of my lab: universal scaling laws in plasmid biology! 📈🧬
👉nature.com/articles/s41467-0…
bugbomb retweeted
Synthetic ecosystems that autonomously and continuously evolve in silico 👾
An Alifer dream we pursue with Flow-Lenia !
If you are interested in complex systems with (1) emergent creatures and (2) intrinsic evolutionary dynamics, go check our new paper !
A 🧵
bugbomb retweeted
We have two identical groups of 8 gauges with anomalous gauge at position (3,1). The degree of anomaly is identical in both groups ~ 8 deg.
Humans have extreme hyperacuity with respect to detecting angular orientation of line segments—needle gauge is so much faster to read. The arc gauges all look the same even though the amount of deviation is the same, about 8 degrees. Even if you concentrate, it's hard to tell which one is off.
bugbomb retweeted
An "idea" that doesn't have an allure by appealing to something beyond the self is so fragile
An epitaph to Cyc. @layer07_yuxi composes the most comprehensive retrospective on Lenat's work that is available to the general public. Spectacular work exhuming dead links from the Internet archive.
yuxi-liu-wired.github.io/ess…
LLMs are the gateway drug to increasingly strange forms of intelligence.
pub.sakana.ai/asal/
2 MegaPower units running open air Brayton cycle for a total of 4 MWe or 2 MWe + 2 on standby. Depending on ISRU demands, tapping off process heat to run high temp reactions (HTSE for Sabatier) could make other designs more attractive.
patents.google.com/patent/US…
Nuclear bros: your challenge is to install a reactor into a Starship to operate on Mars as a power plant. Continuous operation, electrical output, 100 T max mass, 9 m diameter. You can deploy stuff from the Starship onto the ground but there's no subsurface lake of cold water to drill into. Reply with a rough estimate of power output and conceptual design. Remember, reactors and rockets are expensive so we want to maximize power output.
.@CJHandmer have you given much thought on direct thermal tapoff vs just blasting shit with microwaves for ISRU? I imagine combined heat & power is heavy and hard to maintain and I'm guessing you need to be using a lot of heat to justify the complexity.
bugbomb retweeted
It is difficult to introduce genetic modifications into microbial strains during industrial-scale cultivation without compromising fitness. In @mSystemsJ: an approach to guide pathway configurations for enhanced CO2 fixation through metabolic engineering. asm.social/2h7
ALT Contour plot of ATP cost for carbon fixation in molATP/molCO2 for each of the six major microbial pathways with no minimum driving force imposed. The right y-axis indicates an equivalent electron donor reduction potential to the hydrogen concentration. Negative ATP cost values indicate that net ATP is produced. The middle two pathways in blue font are aerobic, all other anaerobic.
The flip side of this: Bob has patiently explained paraconsistent logic to me on 3 different occasions under varying degrees of sobriety, and my empiricism-poisoned brain still doesn't understand.
en.m.wikipedia.org/wiki/Para…
One time, drunk as a skunk, I forced .@bug_bomber to explain exactly what "ray tracing" is in excruciating detail until I finally understood it. In that moment, it was far more difficult to grasp than wild heterodox formal logic.
bugbomb retweeted
Our new perspective article describing the human and non-human primate developmental GTEx projects is now out in @Nature! We outline the scope, vision, opportunities and challenges of these projects here:
nature.com/articles/s41586-0…
My favorite Bob algorithm is the Primorial Class Attendance Function. The product of the first n primes $$P_n\#$$ scales super exponentially which makes Excel grumpy.
Sadly for Bob's students, he will have to mark them all absent until Excel has arbitrary precision integers.
