Mechanisms of cancer growth and survival. Odd tyrosine kinases, autophagy, and the dynamic signaling hub of 14-3-3. @huntsmancancer @UUtah

Salt Lake City, UT
Joined March 2015
Josh Andersen retweeted
🚨Out in @MolecularCell, “Molecular Determinants and Signaling Effects of PKA RIα Phase Separation” by @a_hardy_girl establishes that a non-canonical, active PKA R:C complex in RIα condensates sequesters PKA activity from the cytosol. tinyurl.com/MolDetRIa
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Flashing the U with @JudithSimcox at #DiscoverBMB and flashing back to our shared time at @UofUBiochem
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Congrats to @LopezP_Tania 👇
The #DiscoverBMB Graduate Student Diversity, Equity and Inclusion Travel Award winners poster session starts at 7 p.m. Central in Exhibit Hall 4A. Enjoy camaraderie, good food and incredible research showcased by award recipients.
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Our @ASBMB #DiscoverBMB session on cell signaling and protein phase separation starts at 2:45. Come for great talks and panel discussion!
Today at 2:45 p.m. in Room 217C at #DiscoverBMB: Join us to decipher the mechanisms by which phase separation controls various aspects of cell signaling and the role of post translational modifications in regulating phase separation. Speakers: guidebook.com/g/#/guides/dis…
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Josh Andersen retweeted
Targeted protein degradation/ stabilization are of therapeutic value, but only few E3 ligases and deubiquitinases have been of use for this purpose. Work ⁦⁦@Nature⁩ adds to this repertoire, providing a catalogue of effectors of protein stability. nature.com/articles/s41586-0…
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Josh Andersen retweeted
Check out our new review article on ciliary signaling, now online at @NatRevMCB - a great collaboration with @Hilgendorf_Lab and @ReiterLab!
Our latest review article in NRMCB is out on everyone's favorite signaling organelle, the primary cilium! It was truly a real pleasure to work on this with @Myers_lab and @ReiterLab.
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Josh Andersen retweeted
Nature review article: A break in mitochondrial endosymbiosis as a basis for inflammatory diseases go.nature.com/3OAPC0C
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Happy to see it in print! 👇Intrigued by disease mutations clustering around PTMs #kinase #cellsignaling #proteomics Congrats @Rosh57875462
From the February issue— Integrating #ClinicalCancer and PTM Proteomics Data Identifies a Mechanism of ACK1 Kinase Activation, by Eranga R. Balasooriya, Joshua L. Andersen et al. bit.ly/3OA1lwE @MGHCancerCenter @BYU @huntsmancancer
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Josh Andersen retweeted
Congratulations Alex! Another bit of the ATG9A puzzle Exploring the ATG9A interactome uncovers interaction with VPS13A journals.biologists.com/jcs/…
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We are immensely grateful to @utahcityutah for their generous land donation and for the exciting vision they have created. This new campus in Utah County promises expanded world-class care, breathtaking views, and reduced travel burden for patients: bit.ly/3vTfPkQ
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Thanks to the visionary developers of @UtahCityUtah—Woodbury Corporation & Flagship Companies, along with @VineyardCity, we've received an incredible $20 million land donation. This will pave the way for a state-of-the-art HCI campus in Utah County. bit.ly/3vTfPkQ
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If you’re coming to #DiscoverBMB, please join @Castaneda_lab and us for an interest group on phase separation/condensates and cell signaling. Fantastic speaker lineup! 👇
At #DiscoverBMB 2024, forge connections while discussing phase separation & cell signaling at our interest group, "Signal transduction: an emergent behavior of bimolecular condensates." Hosted by @Castaneda_lab & @andersenlab, you don't want to miss it! asbmb.org/asbmb-today/scienc…
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We’re looking to hire some undergraduates! 👇
Check out this opportunity to work in the @andersenlab with @uofu_science and @huntsmancancer! Visit our website to learn more: our.utah.edu/research-opport… @UofUUndergrad @UUtah
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Josh Andersen retweeted
Alana L. Welm, recipient of the 2023 @AACR Outstanding Investigator Award for Breast Cancer Research, delivered her award lecture this afternoon during #SABCS23. @AlanaWelm @UTHealthSAMDA @AACR
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Josh Andersen retweeted
Our lab at @huntsmancancer @UUtah is hiring a junior-level tech! Come work on fascinating questions in signaling, development, and cancer with a dynamic and collaborative team. Great opportunity for future grad or med school applicants. Please RT! utah.peopleadmin.com/posting…
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Excited to see this new pre-print out! Gets at the role of ubiquitin condensates as platforms for assembly of autophagy machinery. Fun collaboration w @jenscs83 @DavidGBroadbent @ColtenMcewan #autophagy
The formation of ubiquitin rich condensates triggers recruitment of the ATG9A lipid transfer complex to initiate basal autophagy biorxiv.org/cgi/content/shor… #biorxiv_cellbio
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👇Great choice!
We applaud @POTUS Biden's announcement that he will appoint AACR member @KimrynRathmell to succeed @NIHDirector Monica Bertagnolli as the next Director of @theNCI. The AACR looks forward to working with Dr. Rathmell to advance our shared mission. bit.ly/3ucTxJN
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Josh Andersen retweeted
New @biorxivpreprint from our lab by @Qian37774492 on a covalent 14-3-3 molecular glue with the transcription factors YAP and TAZ and using this glue as a 14-3-3 recruiter to sequester nuclear neo-substrates into the cytosol! Thanks to #AppleTreePartners & @themarkfdn biorxiv.org/content/10.1101/…
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If you’re interested in cell signaling and condensates, come join us! 👇#discoverbmb 2024 #SanAntonio
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