Accel & Peak XV lead the 2026 ASK Private Wealth Hurun India Cheetah Index, backing 18 Cheetahs each. Anand Chandrasekaran tops the angel investors with 11 bets. Premji Invest becomes the first family office in the top 10. #CheetahIndex2026 #IndiaStartups

A cancer drug just passed its Phase 3 trial, and the active ingredient comes from Cold War nuclear bomb material the US government was paying to destroy. The drug is actinium-225 attached to a peptide that hunts down a receptor on neuroendocrine tumor cells. Once it docks, the actinium fires off alpha particles that travel only 2 to 3 cell widths before stopping. The tumor cell dies. The healthy cell next door barely notices. The science was the easy part. Actinium-225 is one of the rarest usable substances on earth. For decades, nearly the entire global supply came from a single thorium-229 sample at Oak Ridge National Laboratory, milked about 8 times a year, yielding roughly 1.2 curies annually. Enough for clinical trials and not much else. That was the whole planet's supply. Thorium-229 decays out of uranium-233, material the US produced for its nuclear weapons program. The Department of Energy classified that stockpile as waste and has spent years paying contractors to dispose of it. Then someone realized the waste contained the parent isotope of the best cancer-killing atom we've ever found. Bill Gates's TerraPower now partners with the DOE contractor to pull thorium-229 out of the uranium before it gets destroyed. They've extracted over 15 grams so far. Before this project, about 1 gram existed outside Oak Ridge in the entire world. At full scale, that one recovery effort yields around 90 curies of actinium-225 per year, enough to make 100x more doses than humanity could produce before. Bristol Myers Squibb paid $4.1 billion for RayzeBio, the startup behind this drug, before the Phase 3 even read out. They built a plant in Indianapolis that ships every dose within 3 days of production, because actinium-225 has a 10-day half-life. The medicine decays while it travels. The best cancer-killing atom we know of spent 60 years sitting in a Tennessee stockpile marked for disposal.

Deedy you are right about some aspects of the past, but its more nuanced then this, and likely different going forward. am sticking to the perspective of founders (vs employees & vcs). If you were building for India consumer, the last 5 years have shown that you absolutely could have built significant cos and personal wealth by being in india (>$5b cos - flipkart, zomato, lenskart, meesho, groww, paytm, phonepe, swiggy, policybazaar, nykaa… ) and execs at these places also saw a lot of value being created. I was in a room of startup founders by @ETAwards on friday night and there were a lot of billionaires there! and 50+ other venture backed cos in the $500m-5b range, where also the outcomes have been significant for founders and execs. if you were building for global software buyers, you need to be closer to the customers and the US is that. market insights matter more then cost of engineering. many global software cos have large india teams (zscaler! wealthiest indian american in the US) but the bulk of the value to founders and execs are in the market they serve. it still makes sense for most global founders to be in the US if thats what you are creating, and we have good examples like freshworks, postman and composio where cos started in india and migrated over various points in the past decade. other areas like manufacturing/“deeptech”/atoms based businesses, India has significant advantages and we are just starting to see the outcomes. ather energy ($6b), skyroot ($3b), zetwerk (going public soon) are showing the way, and these cos have far lower costs to develop and manufacture vs other places. finally, there is something to be said for patriotism or impact on soceity. zomato helps employ 1% of india (or something like that) and thats a stepping stone to a brighter future for many. skyroot inspired some young kid somewhere that said i’m gonna do that too. building a enterprise sw product in palo alto is awesome, but for some gives less intrinsic motivation. building in india has many challenges (most self inclicted), but a good choice for many smart people vs a couple of decades ago! we do now have healthy capital markets, a better policy environment, and very smart young people (now enabled by AI!). we absolutely need more risk capital and some of us are working to do that!

SECRETARY RUBIO: For twenty-five centuries since, the Parthenon has stood. Empires have risen and fallen beneath its shadow. And the progeny of the men who built it – the sons of Athens and Rome – have carried their civilization with them to the ends of the Earth. Two and a half centuries after the founding of the American republic halfway across the world from where I stand now, I stand here today – as the Secretary of State of that republic, and as the great-grandson of settlers who arrived in the new world from Spain – I stand here to testify to a debt that no lapse of time, no distance of space, can ever extinguish.

We're thrilled to announce that Yulu has secured US$93 Million in a new funding round led by GEF Capital. The #funding will drive #Yulu's continued leadership across quick delivery and urban logistics. Know more about our #SeriesC round here: yulu.bike/newsroom/yulu-secu…

We have a research team working on thoughts to text, but that looks like a few years away. Maybe the 3rd of 4th version of Temple.

In the U.S. trade war with China, rare earths are a critical battleground. Jon Wertheim reports from the only active rare earth mine in the US that is challenging China's near-monopoly over the strategic metals that are key components in smartphones, robotics, fighter jets, and drones. Sunday. 60Minutes.com

This year we passed 1 million members, crossed $100M in ARR, and now we've acquired MBI, the team behind HMBradley. Most of us ended up at Monarch because of our own money stories. So getting to build alongside people who share our vision, our energy, and our bar for getting it right? That's not a team you pass on. @zbruhnke and his team are starting Monarch Labs, where they'll explore new ways to help people with their money and give us a head start on what's next. We have the same goal as always: better financial health for every household, and less of the fragmentation, stress, and confusion that comes with managing money. With this acquisition it means building what's next while making the Monarch you use every day even better.

Many congratulations to the Moneyview Team, @AccelIndia team and our favourite @subratamitra on the IPO✨✨ Subrata is a pure seed investor at heart. And he’s a legend. Moneyview is his 10th unicorn, almost all Seed Checks (started w Seed in Flipkart). He rarely does podcasts, so good day to share few gems (many counter intuitive!) from his 15 years+ as Seed VC that I am trying to follow: 1. There are 100 reasons to pass on a company. Keep digging for the 1 reason to invest at Seed Stage. 2. Don't take yourself too seriously. Stay a little foolish. 3. Hierarchy kills creativity. Stay weird. 4. Most important thing is to have fun in the journey. 5. The main character of this game is Founder, not the VC. Grateful everyday to be around the folks here who have shaped the Indian ecosystem! We are celebrating today 🧿🍻🍺

SECRETARY RUBIO on AMERICA.GOV PASSPORTS: No printing forms, no drugstore hostage photo, no appointment, no line, no middleman that you're paying to do something that should be available to you.

Justin Verlander says goodbye to his teammates And then holds his daughter’s hand as he leaves the mound 🥹

When you are having a bad day Life isn’t generally a smooth, linear curve. If you zoom in, you’ll see a fairly irregular one, with ups and downs often very close to each other. The same can be said for any single day in our lives. If there are more highs, you feel you’ve had a great day. If you encounter more lows, it becomes a designated bad day. But how much of this is in your control? And how much is just luck? Many a time, you encounter several lows right at the beginning of the day. A bad outcome on a deal you’re pursuing, poor results in your practice matches, an argument with a loved one or some conflict at work. Sometimes you’re just not feeling fully energised. Or you’re in a bad mood without quite knowing why. How your day eventually turns out depends on how well it started, some luck, and what you do when it seems to be heading towards being a bad one. First things first, give your day a jump-start. An early morning workout or yoga, a great cup of coffee, some meditation, a bit of reading, a nice breakfast. Whatever your routine is, make time for it. This ritual gets you ready for the day. Once you’re in the thick of the action, you’ll start sensing your energy fluctuate. That’s when you need to separate what’s under your control from what isn’t. Start with the things you can do something about. In most cases, this means going back to basics and focusing on things you do well. Find areas that are going well and spend more time on those for the day. Do more of the same thing. Instead of picking up something new, focus on closing projects that are already on the right path. There’s usually something nearly done that needs your attention. Finish it well. Getting a few things done helps. Then comes the more difficult part. Dealing with the uncontrollables. The first step is to slow down, breathe and restart. You may have to do this several times during the day. The next is to watch how you react. Before sending an email or text, think twice. Suspend judgement. Keeping your phone away also helps sometimes. Go for a short walk alone. On a day like this, cut down on experiments. Some new conversations can wait. Even with something as small as what to eat, it’s okay to go with the familiar. Have your own “happy drill”. The same music, the same food, the same excerpt from a book. You probably already know a few things that make you feel better. Keep them handy for such days. The parallel in sport would be to go back to safe shots, familiar movements and the drills you’ve practised so many times. When things aren’t going well, doing the basics properly is a useful place to start. Turning around a bad day also gives you a better chance of starting fresh the next morning. Otherwise, it’s easy to carry the frustration forward and begin the next day with yesterday still on your mind. A day which hasn’t gone your way should also probably end early. Hit the sack earlier than usual and give yourself a chance to recover fully. Life has a lot to do with probability. All we can do is keep improving the chances of each day ending well. A collection of good days becomes a good stretch, and sometimes that becomes a purple patch where you get your best outcomes. Many of you might be in the thick of such a stretch right now. You feel like a superhero. Whatever you touch turns to gold, and you can’t remember what a bad day looks like. You’re lucky to be in a stretch like that. Make the most of it. Life will always fluctuate and if you ever find yourself in a trough, some of this may come in handy. When you know you’re getting into a downward spiral, just apply the brakes and slow down.