computational biologists | #datascience #machinelearning in genomics and epigenomics | mom of three wonderful kids
Berlin, Germany
Joined June 2015
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Finally! Our study about nonlinear DNA methylation trajectories during aging is out at @NatureComms!
We have discovered two sudden hypermethylation switches during early-to-midlife and mid-to-late-life stage. (1/4)
rdcu.be/dEj0g
🚀Real-Time Tumor Classification in the Operating Room!🧠🧬
I am super excited that our study was just published in @NatureMedicine!We developed MethyLYZR - a cutting-edge ML framework enabling live molecular classification of brain tumors within an hour. doi.org/10.1038/s41591-024-0…
This milestone was achieved through an incredible collaboration between Max-Planck-Institute for Molecular Genetics, Universitätsklinikum Schleswig-Holstein, Christian-Albrechts-Universität zu Kiel, together with other collaboration partners and experts. 💪
🎉 A huge thank you to the entire team, including @helenekretzmer , Mara Steiger, Franz-Josef Müller, Björn Brändl, Christian Rohrandt, and all our co-authors and collaborators! It was a great pleasure to be part of this team! ✨
Alena van Bömmel retweeted
The handwriting of famous authors - thread 🧵
1. Fyodor Dostoevsky's manuscript draft of The Brothers Karamazov
Alena van Bömmel retweeted
Die Wahlplakate des Postillon sind super und sie treffen ins Mark.
Ein Thread, zum Schmunzeln.
Link zum Text ganz unten.
Quelle für alle Bilder: Der Postillon
Alena van Bömmel retweeted
🚨 Stop chasing the p-value!
Increasing your sample size will always yield a significant result.
Even for trivial differences.
🎮 I created a little interactive playground to illustrate this issue:
react-graph-gallery.com/exam…
Always pair p-values with effect sizes!
A great work of my colleagues! I'm so glad to be part of this amazing team!
Cooperation of Ghost-Driving Genes 🧬
Groundbreaking study in Nature Genetics makes a decisive contribution to understanding how our genes are regulated.
Read more: bit.ly/3C1MurG
@LeibnizFLI @NatureGenet
🔥🧬Finally out!🧬🔥 Check out our latest study in Nature Genetics uncovering a surprising phenomenon of convergent co-regulated promoters cocoProms doi.org/10.1038/s41588-024-0…
🧑🤝🧑I'm happy to be part of such an amazing team!
🧵
- This discovery challenges traditional concepts of promoter architecture, showing that multiple promoters can be epigenetically linked and co-regulated
- Our findings may redefine how we identify target genes of transcription factors and understand regulatory mechanisms
Big thank to my amazing PhD student Tushar Patel for his work and to Steve Hoffmann for his support and productive discussion! It was again a lot of fun to participate at the @DR_E_A_M challenge! Many thanks to the organisers! Stay tuned for the upcoming publication!
FLI Team Achieves Success in International DREAM Challenge on Placental Aging. 🎉
Team ANTS from the @Leibniz_FLI in #Jena achieved second place in the global Placental Clock DREAM Challenge. 🥈 Congratulations!
Read more: bit.ly/3D0Yf1L
Alena van Bömmel retweeted
The Datasaurus Dozen is a collection of thirteen datasets that, despite having nearly identical summary statistics—such as mean, variance, and correlation—exhibit vastly different distributions when visualized. This underscores the critical importance of graphing data to uncover underlying patterns that summary statistics alone may obscure.
#Statistics #DataScience #Research #Science
Alena van Bömmel retweeted
What a cool surprise on a Friday afternoon - our story on the cover of @NatureSMB.
@bulutkarslioglu @MPI_MolGen
Alena van Bömmel retweeted
I am very pleased to see the 2nd survey report of Postdocs from @LeibnizWGL out. It's great that Working Group 1
of the @LeibnizPostDocs Network is continuing this work! Thank you so much @becker_regi and all other team members!
leibniz-postdoc.de/report-of…