SERI-funded #ERCStG Group Leader Structural Neurobiology @psich_en, CV Starr Fellow @PrincetonNeuro, founder of https://xitter.cf/t.co/UljvKCLDIp,@adrianawanner.bsky.social

Joined January 2019
Happy to share the first paper from my journey at @psich towards X-ray connectomics, now out in @naturemethods: nature.com/articles/s41592-0…
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Adrian A. Wanner retweeted
Very excited about this preprint! We use a K-mirror and a tunable lens to flexibly align the two-photon imaging plane with curved biological structures. Great work of PhD student @ShinjinNeuro101, with Fritjof Helmchen, @LucaGodenzini, and many others! biorxiv.org/content/10.64898…
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Fantastic opportunity!
🌟 Applications are open! The Princeton Neuroscience Institute invites exceptional postdoctoral researchers to apply for our CV Starr Fellowship, which provides an attractive salary and research funds. Starr fellows have access to state of the art facilities for experimental research in all of major research areas at PNI, as well as advanced computational resources that support theoretical and quantitative approaches to neuroscience. 🗓️ Deadline: Nov. 06, 2026 🔗 pni.princeton.edu/apply/post…
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Adrian A. Wanner retweeted
Our work with José-Alain Sahel's team and @GenSightBio on optogenetic vision restoration is now published in @NEJM The treatment was safe in all 10 participants, with visual improvements in several patients. 📄 doi.org/10.1056/NEJMoa260221… #Blindness #Optogenetics #IOBBasel
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📢 We’re hiring! PNI is seeking a full-time Lecturer in Computational and Cognitive Neuroscience to teach undergraduate and graduate courses in computational modeling and human cognitive neuroscience. Priority consideration: Nov. 30 Apply: apply.interfolio.com/193741
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Adrian A. Wanner retweeted
Here's Tristan Buckmaster's statement. (You've probably seen bits of it quoted here today, but the whole thing is worth reading.) cims.nyu.edu/~tristanb/state…
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Adrian A. Wanner retweeted
Congrats @SebastianSeung , @zhihaozheng , et al!
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Even if we have ways to break up neural networks into interpretable parts, the largest weights between those parts can be confusing. Why is that? In our new research note, we study the *weight* superposition that causes interference weights.
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Adrian A. Wanner retweeted
Harvard Neurobiology + Kempner are hiring a tenure-track Assistant Professor in computational neuroscience. The search is broad; researchers combining computational and experimental work (including nonhuman-primate research) should apply! academicpositions.harvard.ed…
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Adrian A. Wanner retweeted
Just published yesterday, the #BANC! A full central nervous system (CNS) connectome of a limbed animal enables us to trace sensory-motor arcs and understand how the CNS controls the body. rdcu.be/fncjS #neuroscience @Nature, Video by @quorumetrix, sound on! 1/18
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Huge congratulations, awesome to see this out!
It took endless hours in the lab and a massive effort, but we're finally here: Eyewire II is officially out! Huge thanks to our amazing co-authors and everyone else who supported us along the way. So grateful for the hard work—it’s been a privilege pushing through this together.
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Adrian A. Wanner retweeted
Meet Eyewire II: a new connectomic resource for the mouse retina. ~1 mm² of retina at nm resolution, with synapses and circuits of ca. 100,000 neurons + visual responses from the ~400 neurons shown in the video! Preprint: doi.org/10.64898/2026.05.28.… Data: eyewire.ai/
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Adrian A. Wanner retweeted
Our SPATIAL platform enabled the discovery of a previously undescribed microglial subpopulation in human Alzheimer's disease brain. 704,706 cells. Full morphology. One platform.
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Adrian A. Wanner retweeted
Excited to share our paper published today in @NatureNeuro: nature.com/articles/s41593-0… Using spatial proteomics, we identified a plaque-associated microglial population that emerged only when morphology and spatial context were integrated with protein expression.
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If you’re in or around Baden today, drop by... because Pint of Science Switzerland is back in town for a third time this year! 🧠 "Cracking the Brain's Code" 📆 Today: 19 May, 2026 📍 Kulturhaus Royal, Bahnhofstrasse 39 ⏰ Doors open: 6 PM pintofscience.ch #pintofscience
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Big news for the @Princeton neural circuit research community ! 🔬🧠 Thanks to an award from @princetonideas, we're acquiring a new light sheet fluorescence microscope. Paired with LICONN tissue expansion, it maps axons & synapses at nanoscale resolution. research.princeton.edu/news/…
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Adrian A. Wanner retweeted
Research to Prevent Blindness @RPB_org Award to Enable Transformational Scientific Milestone in Neuroscience and Vision Science - AKA Eyewire II! rpbusa.org/news-press/resear…
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Adrian A. Wanner retweeted
Can generative AI accelerate neuroscience? Excited to share MoGen at ICLR 2026!🧠 We use point cloud flow matching to generate high-fidelity 3D neuron fragments, capturing intricate details like dendritic spines.
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Great opportunity to shape the future of X-ray connectomics (and much more 😉): PSI is looking for a new head of the Center for Photon Science psi.ch/en/hr/job-opportuniti…
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