@_johnmcd

Plant-oomycete interactions

 Virginia Tech, USA
spes.vt.edu/faculty-staff/faculty/mcdowell-john.html
Joined March 2013
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  • Following422
  • Followers1.7K
67Media
Thrilled that HYPs found a home @CellGenomics 🤩
Cell Genomics@CellGenomics29 May 2024
A gene with a thousand alleles: The hyper-variable effectors of plant-parasitic nematodes dlvr.it/T7YcGY

A gene with a thousand alleles: The hyper-variable effectors of plant-parasitic nematodes

Sonawala et al. describe how the HYP genes in plant-parasitic nematodes can harbor thousands of alleles. They elucidate the “rules” underlying variation in the hyper-variable domain (HVD) of HYPs and...

cell.com
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John McDowell retweeted
Jacob Barney@jnbarney9 Feb 2024
The @ISWGvt is thrilled to announce an invasive species-based cluster hire @virginia_tech for 7 new tenure track faculty! We are seeking individuals who possess the skills to bridge disciplinary divides, drive innovative solutions, and engage in team science. 🧵
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Critical thinking and deferring to experts
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Abstract submission and registration are now open for the Oomycete Molecular Genetics Network 2024, Asilomar, Pacific Grove, CA, USA from March 10-12. Please find the details for travel, hotel booking, abstract submission, meeting registration at oomycetemolgen.github.io/mee…
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Mahmut Tör@MahmutTor9 Jan 2024
Yesterday, we had a productive team meeting discussing RNA and updating on #BBSRC and #NSF projects. Fruitful collaboration made it enjoyable and fun @niabgroup @_johnmcd @UoW_MPMB_RU @UniofExeter
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I am super excited that our paper (my 1st 1st author paper 🥹) in #pnas is finally out! We found that the #chytrid s Bd & Bsal have 2-speed genomes previously only found in #plant #pathogens.Also exciting: #transposons appear to be shaping their genomes & drive pathogenicity. 1/2
Rhys Farrer@RhysFarrer13 Jan 2023
Our new paper is published in #pnas on the 2-speed genomes of #chytrid pathogens of amphibians (Bd and Bsal). Repetitive sequence inc. transposons appears to be shaping their genomes and driving their pathogenicity pnas.org/doi/10.1073/pnas.22… @theresa_wacker
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If the pandemic was whispering to us about air quality, the wildfires are screaming to us about it🌲🔥 @linseymarr via @NYTOpinion #CanadaFires #NYCsmoke nytimes.com/2023/06/07/opini…

Opinion | What Wildfire Smoke, Gas Stoves and Covid Tell Us About Our Air (Published 2023)

Wildfire smoke underscores the need for better indoor air quality.

nytimes.com
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Mutual potentiation between surface receptor- and intracellular receptor-mediated immunity, also in mammals cell.com/cell/fulltext/S0092… @sardineboy_DING @BrunoNgou @HeeKyungAhn1

NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs

NLRP12 is an immune sensor that activates cell death and inflammation when it senses heme and pathogen-associated molecular danger signals indicative of hemolytic diseases.

cell.com
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John McDowell retweeted
Gang Yu@GangYuPlant8 Jun 2023
WeiTsing, a pericycle-expressed ion channel, safeguards the stele to confer clubroot resistance: Cell cell.com/cell/fulltext/S0092…

WeiTsing, a pericycle-expressed ion channel, safeguards the stele to confer clubroot resistance

WeiTsing, an ER-localized calcium-permeable channel, enables pericycle to prevent Plasmodiophora brassicae colonization in stele, thereby conferring a broad-spectrum clubroot resistance.

cell.com
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This really is no joke. People act like toxic environments in research is the price we have to pay for genius to succeed. But have we considered that there might be more success in positive work environments where everyone feels properly supported? /1 nature.com/articles/d41586-0…

A mental-health crisis is gripping science — toxic research culture is to blame

Nature - With researchers reporting high rates of anxiety and depression, calls are growing to fundamentally change science before it’s too late.

nature.com
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Superb Molecular Plant @MPlantPCom from @dejongepmi and @GStringlis Cell type-specific transcriptomics reveals that root hairs and endodermal barriers play important roles in beneficial plant-rhizobacterium-interactions #Pseudomonas_simiae cell.com/molecular-plant/ful…

Cell-type-specific transcriptomics reveals that root hairs and endodermal barriers play important...

This study investigates how the epiphytic plant-beneficial bacterium Pseudomonas simiae WCS417 affects different root cell types of Arabidopsis thaliana using cell-type-specific transcriptomics....

cell.com
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Everyone should feel safe, welcome and valued at work. ‘This deserves our attention.’ New data highlight LGBTQ scientists’ workplace challenges | Science | AAAS science.org/content/article/…

‘This deserves our attention.’ New data highlight LGBTQ scientists’ workplace challenges

Researchers hope large study spurs more support for LGBTQ scientists

science.org
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and one little teaser: research on this fascinating topic is still continuing in #theustunlab @LanginGautier is preparing his manuscript explaining the last puzzle pieces of how the proteasome coordinates the tradeoff btw. growth & defense, surprise photosynthesis plays a role 😅 – at Bochum, Germany
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How to convert host plants into nonhosts dlvr.it/Sq2W5v

How to convert host plants into nonhosts

Recent research demonstrates that undermining interactions between pathogen effectors and their host target proteins can reduce infection. As more effector–target pairs are identified, their struct...

cell.com
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John McDowell retweeted
New Phytologist@NewPhyt26 May 2023
Proteins released into the plant apoplast by the obligate parasitic protist Albugo selectively repress phyllosphere-associated bacteria Gómez-Pérez et al. @Kemen_Lab 📖ow.ly/w7mZ50OxVPg
Proteomics of Albugo candida apoplastic proteins from infected Arabidopsis thaliana leaves.

ALT Proteomics of Albugo candida apoplastic proteins from infected Arabidopsis thaliana leaves.

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We're looking for a postdoctoral researcher to join our group in UW Seattle. We're funded to work on signaling and synthetic biology of plant cell surface receptors 🧬🌱🐛 Details attached -- please RT!
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Emily Breeze@emilybrz23 May 2023
Our new paper on local and systemic jasmonate signalling during SAR is finally out! (FYI our reporter is pronounced 'jiss' to rhyme with 'hiss' and 'miss'. 😉) biorxiv.org/content/10.1101/…

Rapid local and systemic jasmonate signalling drives initiation and establishment of plant systemic...

Successful recognition of pathogen effectors by plant disease resistance proteins (effector triggered immunity, ETI) contains the invading pathogen through a localized hypersensitive response (HR)....

biorxiv.org
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"The genome of the oomycete Peronosclerospora sorghi, a cosmopolitan pathogen of maize and sorghum, is inflated with dispersed pseudogenes" by @KIGFletcher et al in #G3Journal doi.org/10.1093/g3journal/jk…
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John McDowell retweeted
Pestinfo Wiki@PestinfoW21 May 2023
Members of the genus #Phytophthora cause serious #plant #diseases, guide on how to identify its 203 species using molecular and morphological characters in @PlantDiseaseJ by @gloria_abad3 and others - doi.org/10.1094/PDIS-02-22-0…
Phytophthora characters useful for the identification of Phytophthora species include the morphology of sporangia, zoospores, sporangiophores, chlamydospores, hyphal swellings, oospores (gametangia) and the colony shape (Fig. 4 of article).

ALT Phytophthora characters useful for the identification of Phytophthora species include the morphology of sporangia, zoospores, sporangiophores, chlamydospores, hyphal swellings, oospores (gametangia) and the colony shape (Fig. 4 of article).

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Kyle Fletcher@KIGFletcher20 Sep 2021
Firstly, we have re-sequenced and re-assembled the genome of the oomycete that causes downy mildew on spinach (Peronospora effusa), using @PacBio HiFi reads. From this, we resolve 17 T2T chromosomes. Remarkably 16 of these were assembled without gaps! biorxiv.org/content/10.1101/…
A circos plot detailing features of the 17 chromosomes of Peronospora effusa.

ALT A circos plot detailing features of the 17 chromosomes of Peronospora effusa.

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