Cardio-Oncologist, Cardiac Imaging Specialist, Research Fellow, Intrinsic Geek, Sport Fanatic, (sometimes) unconsciously hypersomniac 🇲🇾🇦🇺
Melbourne, Victoria
Joined March 2021
- Tweets57
- Following150
- Followers57
- Likes184
Sean Tan retweeted
Routine preprocedural fasting for #PCI may not be necessary for all. With low rates of procedural intubation, targeted fasting for high-risk groups may be a better approach. #AHAJournals @HersonMeg @_SeanXTan @MonashHeart @MonashVHI ahajrnls.org/4ge8ePj
Patients with HFrEF have ⬆️ incident cancer but undergo ⬇️ cancer screening than the general population (despite expressing interest).
Should we include cancer screening in HFrEF programs?
japscjournal.com/articles/ca…
#cardiooncology #reversecardiooncology
@MonashVHI
Many practical challenges affect ASCVD prevention in patients with cancer treated immunotherapy. Huge scope for opportunistic screening and implementation research in #CardioOncology @ProfSNicholls @profevasegelov @ajnelson @MonashVHI @ESC_Journals
doi.org/10.1093/eurjpc/zwae2…
#CardioOncology is a collaborative field but discrepancies in guidelines used by each stakeholder involved in #CardioOnc care can lead to differences in cardiotoxicity Dx and Rx
Much work to be done to unify our approach in Aus
@ProfSNicholls @MonashVHI
sciencedirect.com/science/ar…
Excited to share our data on ASCVD events among cancer patients treated with ICIs
CV risk factors are commonly undertreated and should be targeted to improve cancer survivorship #cardioonc
@ProfSNicholls @profevasegelov @ajnelson @MonashVHI
sciencedirect.com/science/ar…
Sean Tan retweeted
🌞 SOCRATES trial
🔍 Testing whether a common cholesterol-lowering drug can prevent heart disease in #melanoma patients who have been treated with #immunotherapy.
👫 180 melanoma patients.
🌏 12 sites across Australia.
👉 masc.org.au/socrates/
@MonashVHI @ProfSNicholls
Let’s go @TheMatildas! Most nerve wrecking but easily best live match I’ve seen @FIFAWWC #TilitsDone – at Brisbane, Queensland
Sean Tan retweeted
The SOCRATES clinical trial has a new site open!
Led by the @MonashVHI and @MASC_Trials team, SOCRATES investigates whether taking a statin can prevent cardiovascular disease in melanoma patients.
More: masc.org.au/socrates
The SOCRATES trial is now open at Latrobe Regional Health, led by site PI Dr Bhavini Shah. Eligible patients can access this trial without travelling to Melbourne. SOCRATES is testing if taking a statin can prevent heart disease in #melanoma patients.
masc.org.au/socrates/
Sean Tan retweeted
The SOCRATES trial is now open at Latrobe Regional Health, led by site PI Dr Bhavini Shah. Eligible patients can access this trial without travelling to Melbourne. SOCRATES is testing if taking a statin can prevent heart disease in #melanoma patients.
masc.org.au/socrates/
Sean Tan retweeted
I was watching Lord of the Rings last night and realized there are many parallels with academia!
A thread 🧵👇
Sean Tan retweeted
Just accepted in JACC: Asia @JACCJournals our paper examining Asia-Pacific Investigators and Asian Enrollment in Cardiometabolic Trials between 2011-2020 @ajnelson @khungkeong @ProfSNicholls @Scherer_RAH @lamcardio @chanchal5688 @WongChrisX
Sean Tan retweeted
Can we prevent #HeartDisease after #Cancer? 🫀🎗️
Cardio-oncology is a new field born out of the necessity to address the increasing burden of heart disease among people with, or who have, survived cancer.
Dr Sean Tan explains in Monash Lens: bit.ly/462rZW2
Sean Tan retweeted
Prevention is key this #HeartWeek! 🫀
@MonashVHI and @MonashHealth visited State Parliament, conducting Heart Health Checks with @Novartis and @Wesfarmers
@MaryAnneThomas MP received her heart check and spoke with @ProfSNicholls about the importance of regular screening.
Patients receiving immune checkpoint inhibitors for cancer routinely have their BP checked when they attend for treatment.
Could we be repurposing this for hypertension screening?
nature.com/articles/s41371-0…
@ProfSNicholls @ajnelson @profevasegelov @MonashVHI #CardioOncology
Reperfusion criteria used to determine success of fibrinolysis for STEMI may miss up to 9% of occluded culprit arteries.
Time to rethink the criteria? Or have lower threshold for early cath with #RadialFirst?
@MonashVHI @DerkPol @ajnelson @ProfSNicholls
asiaintervention.org/article…
Sean Tan retweeted
COORDINATE cluster RCT in 43 clinics across the US:
- n=1049, T2DM + ASCVD. Age 70, 17% Black.
- Multi-faceted intervention: QI | audit & feedback | education
- Endpoint: Prescription @ 12mo: high-intensity statin + RAASi + SGLT-2i/GLP-1RA:
- 14.5 vs. 37.9%, p<0.001
Sean Tan retweeted
#Exclusive: Immunotherapy could be a game-changer for melanoma patients, but the life-saving treatment gives them with a greater risk of heart disease. Melbourne researchers hope a simple cholesterol-lowering pill could reverse the risk and save hundreds of lives | @CaitlinDugan
Glad to be part of the SOCRATES trial to improve🫀health in patients with #melanoma. We’re open for recruitment and looking for sites - tele-trial options are available.
Please reach out or share with anyone who may be interested!
@ProfSNicholls @MonashVHI @MASC_Trials #CardioOnc
Our new SOCRATES clinical trial aims to determine if a common cholesterol medication can reduce the risk of heart attacks in melanoma patients treated with immunotherapy. Read more: masc.org.au/cholesterol-medi…
@MonashVHI @Cabrinihealth @MonashHealth @MonashUni #Melanoma
Sean Tan retweeted
NEW: Cardiac MRI utility for Ibrutinib Cardiotoxicity
jamanetwork.com/journals/jam…
*Cardiac injury (fibrosis) is prevalent, and predicts future cardiotoxic events in cancer patients*
Thanks to @JAMAOnc for publishing this work.
#CardioOnc #hematology #CLL #Ibrutinib #WhyCMR
Sean Tan retweeted
SOCRATES trial is now open for enrolment at @Cabrinihealth, Melbourne and is testing if taking a statin can prevent heart disease in patients with #melanoma treated with ICIs. This treatment could improve long-term outcomes and survivorship. masc.org.au/socrates/
@MonashVHI
