@_Sam_Edwards

PhD student at UCLA. Interested in all things RNA. She/her

Joined October 2016
  • Tweets37
  • Following112
  • Followers52
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The most recent story from @Plathlab is out in Nature! Read more about how Xist mediates heritable gene silencing on #ChrX. Happy to be part of this work! nature.com/articles/s41586-0…

A protein assembly mediates Xist localization and gene silencing

Nature - A protein condensate formed by multivalent interactions between the long non-coding RNA Xist and specific RNA-binding proteins drives the compartmentalization required to perpetuate gene...

nature.com
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I love this. Such an important thing to remember as a mentor, teacher, employer, etc.
Chris Audu MD, PhD@ChrisAuduMD4 Jul 2020
Replying to @bone00afide @bschapiroMD
Thanks so much! I’ve learned that people don’t care how much you know until they know how much you care.
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We are very pleased to announce the outstanding members of our Inaugural Advisory Board. Each of these scientists have made a tremendous impact on their science communities and we look forward to their contributions to the advancement of The Network. Onward together 🙌🏽
Photos of Drs. Tracy Johnson, Nyasha Chambwe, Stacey Finley—inaugural members of the Network Advisory Board.

ALT Photos of Drs. Tracy Johnson, Nyasha Chambwe, Stacey Finley—inaugural members of the Network Advisory Board.

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Congrats @TheTracyLab, an amazing mentor, scientist, educator, and now Dean!
HHMI
@hhmi_science27 May 2020
Congrats to HHMI Professor Tracy Johnson (@TheTracyLab), who was named Dean of the @UCLA Division of Life Sciences! newsroom.ucla.edu/releases/t…

Tracy Johnson named dean of the UCLA Division of Life Sciences

Johnson, whose research focuses on understanding mechanisms of gene regulation, will take the helm on Sept. 1.

newsroom.ucla.edu
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In these days without conferences, we need to find new ways to communicate our science. I'm not going to say that I know the right or wrong way to do this. But the right way is with Lego. @Afarnti @PNASNews
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A few tips and tricks to think about: -create daily goals and an hourly schedule for yourself -experiment with different motivational strategies (sticker charts work great for adults, too!) -don't go it alone - form a group and check in with each other at least once a day
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Congrats to Aaron van Loon for taking the cover image in the current issue of @JCellBiol !
Journal of Cell Biology@JCellBiol31 Jan 2020
Researchers @UCLAMBI @SynthSysEd show that cortical contractions promote the formation of microridges on #zebrafish skin cells by reducing surface tension bit.ly/2u6y9r3
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Sam Edwards retweeted
Anthony Leung@LeungLab4 Feb 2020
Excited to share our work @MolecularCell on a genome-wide pathway that selectively degrades mRNAs with highly-structured 3'UTRs. This structure-mediated RNA decay (SRD) pathway senses the overall base-pairing density, but not defined sequences/structures. dlvr.it/RPJz1L
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Sam Edwards retweeted
Manny Ares 🥑@RiboGuy4 Feb 2020
Learning research means doing research: @TheTracyLab “If a kid wants to play soccer, you don’t say, ‘You have to 1st learn all the rules, watch other people play & read about the soccer greats, & maybe in a couple years, we’ll let you kick the ball.’ No!” ucla.in/2GrGHeD

Hundreds of UCLA students publish paper analyzing 1,000 genes involved in organ development

The results should be useful to scientists studying genes involved in sleep, vision, memory and many other processes in humans.

newsroom.ucla.edu
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It's here!!! science.sciencemag.org/conte… OMG! OMG! 😱😱😱
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Thrilled to share our latest work with the bioinformagician @kiminsigne. We measure promoter activity of 500,000+ sequences spanning the entire E. coli genome with 8x coverage and systematically mutate discovered promoters to identify regulatory elements.
bioRxiv@biorxivpreprint6 Jan 2020
Genome-wide Functional Characterization of Escherichia coli Promoters and Regulatory Elements Responsible for their Function. biorxiv.org/cgi/content/shor… #bioRxiv
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Have you seen all these recent spliceosome #cryoEM structures and just wished you could see the bigger picture beyond all the snRNPs and RNAs and a million protein names? Check out our review! annualreviews.org/doi/abs/10… Minimum detail, many pretty pictures, and LOTS of MOVIES
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WOW WOW WOW Reconstituted Cohesin caught live extruding DNA loops! Turns out it needed an energy boost from its friends NIPBL and MAU2 "single human cohesin complexes form DNA loops symmetrically at up to 2.1 kbp/second." Iain Davidson et al., Peters lab science.sciencemag.org/conte…
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If you want to have good ideas, you need to have a lot of ideas, and that means you need to have a lot of bad ideas. And, you need to have the courage to look closely and be honest with yourself in order to separate the good ideas from the bad ideas. Not easy, but so worth it.
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I get many messages from aspiring black scientists who say they hardly see scientists that look like them online/IRL. So I want to spend time highlighting black scientists, medics, engineers, mathematicians and techies! Introduce yourselves below & I’ll be retweeting👨🏾‍🎓👩🏿‍🔬👩🏽‍🏫👨🏿‍🏭🧪🔭
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Happy RNA Day from the Johnson Lab--the best lab ever!! Thank you @TREnD for the 5' cap! @LeungCal @LAThurlow @AzadeeAzad @_Sam_Edwards @sokonkwo_
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Unexpected item in the western blot area @OCDEM 🦄
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This is so cool!!!
Ben Engel@bengeliscious29 Jul 2019
Our cryo lift-out paper is online! Native #ribosome structures inside a #Celegans worm. Congrats to my amazing colleagues Miroslava Schaffer, Julia Mahamid, Stefan Pfeffer, and Jürgen Plitzko. This lift-out makes me hold my breath... every time!😬😮PHEW!😁 nature.com/articles/s41592-0…
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