Systems Pharmacology and Biology Lab at @DepBiomedicine. Exploit metabolic weaknesses for therapeutic applications.
Department Biomedicine, Basel
Joined January 2021
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Zampieri Lab retweeted
Great news from the Apostolova lab @DepBiomedicine! In a recent study led by @ApostolovaPetya & Robert Zeiser (Freiburg, Germany), extracorporeal photopheresis safely treats immune-related adverse events from immune checkpoint inhibitors, with a 92% response rate. Adiponectin helps reduce inflammation while sparing anti-tumor immunity. Congrats! cell.com/cancer-cell/fulltex….
@Cancer_Cell #CancerResearch #Immunotherapy #Collaboration #ECP #ICI #irAE
ALT In a collaborative effort, Petya Apostolova and colleagues found a way to combat immune-related adverse events during immune checkpoint inhibitor treatment, here shown in action. (Image: Adobe Stock, KI)
Zampieri Lab retweeted
📢📜Papers from our people!
Rentsch Lab @NCCR_AntiResist 👉onlinelibrary.wiley.com/doi/…
Out today @Nature from @BumannLab 👉nature.com/articles/s41586-0…
In @NatureBiotech from @ZampieriLab 👉 nature.com/articles/s41587-0…
In @NatureMicrobiol from @knutdrescher Lab 👉nature.com/articles/s41564-0…
Zampieri Lab retweeted
Researchers in @ZampieriLab @DepBiomedicine developed a method to study how more than 1,500 drugs affect cellular metabolism. Using high-throughput metabolomics, they uncovered new drug mechanisms & potential cancer therapies. Future work will focus on personalizing treatments. @NatureBiotech 🔗nature.com/articles/s41587-0…
#Metabolomics #SystemsPharmacology #DrugDiscovery #CellularMetabolism #HighThroughput #PharmaceuticalResearch
ALT Image generated by ChatGPT on cellular metabolism and high throughput metabolomics. It visually illustrates the complexity of molecular pathways and the advanced technology used in metabolite analysis.
We are very excited to share new recent research from our lab! This has been a long-time effort, involving several fantastic group members and collaborators (@pedrobeltrao and @Jürgen) with @LaurentzSchuhk1 on the driving sit.
A human metabolic map of pharmacological perturbations reveals drug modes of action go.nature.com/3CreANg
Zampieri Lab retweeted
Thank you European Proteomics Association for the JPA Proteome Pioneer Award in recognition for our group's work in this field. The award promotes "the principles of sharing and integrating resources for the development of excellent research" which is something we do strive for.
Here are the 2023 @EuPAProteomics Awardees! They will personally receive their prizes on Oct 22 at #HUPOEuPA2024. Congratulations to
@Sigridvrhlst, Laurent Gatto, @maurinefucito, @pedrobeltrao,
@DemichevLab, @akadfmfm !🥳
We are so proud of our joint team effort as heavy coffee-drinkers resulting in a special award! An 18k golden coffee bean!
We have a new Postdoc position in quantitative biology available! Please check the details here:
jobs.unibas.ch/offene-stelle…
It was nice to meet and discuss with all collaborators of the Sinergia grant "Metabolic reprogramming by selective autophagy" from the labs of Fulvio Mario Reggiori and Jörn Dengjel, in Aarhus, Denmark.
A new movie is now online about our Department of Biomedicine!
vimeo.com/1000667048
We are happy to welcome a new lab member: Huanding Ji, staying with us as an rotation student. Welcome!
In today's journal club, we discussed this comprehensive study on CedA's mechanism of action as transcriptional regulator and its role in mitigating effects of oxidative and antibiotic stress.
nature.com/articles/s41594-0…
In our today's journal club:
doi.org/10.1016/j.celrep.202…
The authors demonstrate transcription factor (TF) activities to be predictive biomarkers for genetic dependencies and therefore cancer vulnerabilities.
Zampieri Lab retweeted
Check out our new method to read library barcodes and measure metabolites of CRISPRi strains with #massspec. Works almost in real-time: biorxiv.org/cgi/content/shor…
Zampieri Lab retweeted
Congratulations to the winners of the Best Poster Awards during the @SNE_ChemBio retreat!
🏆 Xingyu Liu (@Xingyuu_Liu, @LcsoLab)
🏆 Terézia Dorčáková (@ZampieriLab)
🏆 Henriette Lämmermann (@RiveraChemLab)
Sponsored by @spirochrome, Milian Dutscher group & Witec 🙌
Congratulations to Terezia for the Best Poster Award at the SNE Chemical Biology Annual Retreat! 🥳👉👈
@SNE_ChemBio
Finally our beloved mass-spec also managed to get installed in its originally intended lab space for good.
In our today's journal club:
nature.com/articles/s42255-0…
This is an impressive work that lays the foundation for new potential antibiotics!