Interrogating the functional interactions of motor and decision circuits that lead to behavior. (he/lab - not official)
Carnegie Mellon University
Joined October 2018
- Tweets1.8K
- Following831
- Followers1.7K
- Likes1.8K
Pinned Tweet
A fun article about our work and the Olympics.
There's some interesting relationships between skiing and basal ganglia function
@CmuScience @ahmari_lab @BarbShinn
theconversation.com/hesitati…
super excited to be giving a talk today at University of Bordeaux. thank you Nicolas Mallet for the invitation!!!
Here's the tweetprint on pain, blocking its affective content, and its effect on behavioral and neural dynamics!
🧠⚡️💊New @Nature publication !
Mimicking opioid analgesia in cortical pain circuits
We built a brain-behavior framework to decode spontaneous chronic pain in mice—and to biologically mimic morphine with a synthetic opioid gene therapy
nature.com/articles/s41586-0…
@PennMedicine
Hot off the @Nature press! A-SOiD behavior library developed specifically for pain studies quantifies a new chemogenetic gene therapy that targets opioid circuit in ACC without addictive properties
@FlyBottleEscape @CmuScience @cmuneurosci
nature.com/articles/s41586-0…
I'll let Greg do the tweetprint, but he led a Phenomenal interdisciplinary team effort. Great science in every way.
It's open too! Also part of the paper, you can build your own behavior rig with full analysis software for a tenth the price of commercial. Inquire if interested
So proud of @MattGeramita and his stellar work on striatal dynamics, decisions, and impulsivity. Pertinent for thinking about prob vs deterministic frameworks too.
Also, suggests indirect may be doing more(cognitive?) than just opposing direct pathway
nature.com/articles/s41593-0…
Come see Paul present his very cool data + analysis today at 1pm @SfNtweets
If you're at SfN, stop by my teeny tiny nano talk Sunday at 1:
"Neural population dynamics during naturalistic versus task-related behavior" w/
@YttriLab
@Markolas11
@adenoeagle
NANO017.01
Huh, it's been 8 months since I was on here. Better late than never. I hope this new-ish paper will challenge people to think about the interpretations of our models
STRIATUM SUPPORTS REINFORCEMENT AND NOT ACTION SELECTION (!!!)
cell.com/cell-reports/fullte…
@CmuScience @cmuneurosci
When applied contra, ipsi, or bilaterally to left turns, the effect was the same: D1/D2 stim biased mice to turn left more often, regardless of the side of stim. Note, bias is incomplete and did not induce an action, consistent with learning but not action selection
excited to be giving a talk @ UPenn today, with invite from @Fuccillomarc and @FlyBottleEscape
A preview of my first slide....
I'm revamping a masters-level Systems Neuro course this spring.
Please HMU with your favorite reviews and perspective pieces! Extra points for approachable and/or thought-provoking.
Any topic is welcome! I might end up biasing to the BME-heavy audience
I'm still chewing through this one, but I think it's a keeper
cell.com/trends/neuroscience…
