@WiegeringLab

Targeting mRNA translation in colorectal cancer @Uni_WUE, Department of Molecular Biology & Biochemistry

 Würzburg, Germany
biozentrum.uni-wuerzburg.de/molbio/research-groups/ag-wiegering/
Joined March 2019
  • Tweets80
  • Following160
  • Followers142
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So proud! Our newest article about RNA Pol I inhibition and it's effect in #colorectalcancer can now be found online @MolOncology: doi.org/10.1002/1878-0261.13…. Very happy to share our results and progress in #CancerResearch with everyone! 👨‍⚕️👩‍⚕️👩‍🔬👨‍🔬🧫🧪

FEBS Press

Loss of APC, the initiating event in the adenoma carcinoma sequence for CRC, induces the expression of RNAPOL1, and subsequently upregulates rDNA transcription. Targeting RNAPOL1 with a specific...

febs.onlinelibrary.wiley.com
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Very happy to announce that our latest research about RNA Pol I inhibition in #colorectalcancer cells was recently accepted for publishing @MolOncology 🥳 We say thanks to @MYCGyvers, @_WolfLab, @DiefenbacherL and all the other contributors! 💐
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WiegeringLab retweeted
Eilers Lab@MYCGyvers21 Apr 2022
Replying to @martin_eilers
@martin_eilers wraps up our 2.5 day retreat - with prospects & challenges for the future. Thanks to everyone for intensive discussion, cool presentations and a lot of fun! @_WolfLab, @DiefenbacherL, @Gbrlbchl Lab, @_BurgerLab, @WiegeringLab
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Many thanks to our Post-Doc @JBiaynaRodrguez, enlightening us about CRISPR screens and their challenges in organoids 🧬✂️
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Special session today about organoids and how we can profit from them in our research. It's a great pleasure to listen to @KaiKretzschmar, sharing his extensive know-how in this field with us. 🔬🧫
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It's a pleasure to have @S_Schilb as guest speaker on our retreat, elucidating an updated model for RNAP II transcription Initiation. Happy to hear your talk!
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WiegeringLab retweeted
Eilers Lab@MYCGyvers20 Apr 2022
Fantastic line-up of speakers today. We move from highly complex immune models and ILCs back to intracellular mechanisms. @WiegeringLab is starting with translation after breakfast. @cogiac, @AbdallahHatem4 , @leonie_uhl and @DimvPapad will present from the Eilers Lab today.
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Starting our 2nd day of retreat and looking forward to many interesting talks! Our PhD students Hanna & Ivana presented a great overview of their projects, dealing with translation regulation in #colorectalcancer and potential therapeutic targets 👩🏼‍🔬👩🏻‍🔬
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Exciting first day of our department-intern retreat in beautiful Rothenburg o.d.T. together with @DiefenbacherL, @_WolfLab, @MYCGyvers & @_BurgerLab. Really looking forward to our guest speaker @GeorgGasteiger 🥳
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Very funny 🐼 and delicious Tapas-Tuesday with (almost whole) lab group 🌮🦐🦑🍷🍽️
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Congrats! 🤩
@diefenbacherlab.bsky.social@DiefenbacherL28 Mar 2022
What a start to this week and end of this month 😃 two papers (provisionally) accepted!! So proud of my team @Uni_WUE @MSNZ_wuerzburg @Uniklinikum_Wue!! @crypt_tales @OliverHartman14 @NikiPahor @StrahlenThomas @FussTeresa and former member @CristianPG_mlg. Well done!
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Amazing news!! Our latest application for funding was accepted by the Wilhelm Sander-Stiftung 🥳 Great chance to identify essential transl. factors in #ColorectalCancer. Thanks goes to all contributors, especially the @_WolfLab, who are also involved in this exciting project 👩‍🔬👨‍🔬
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Congratulations @KaiKretzschmar @MSNZ_Wuerzburg on the new @ERC_Research Starting Grant (1,5 million euros) for the project #OralNiche: Why oral #cancers are so heterogeneous. ➡️go.uniwue.de/ercst-kretzschm… #ERCStG @krebshilfe_bonn
Dr Kai Kretzschmar. Picture: Angela Riedel / University of Wuerzburg

ALT Dr Kai Kretzschmar. Picture: Angela Riedel / University of Wuerzburg

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New year, new chances! 🧬🔬🧫 We are happy to announce that during the last year our group has obtained many new lab members and we are really looking forward to an exciting scientific year! #colorectalcancer #cancerresearch #proteintranslation
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We're hiring! Looking for an exciting 3-year postdoc position funded by @Krebshilfe_Bonn dealing with colon cancer, organoids, mouse models in an inspiring research environment with great colleagues? Check this out @Uni_WUE @GSLSUniWue biozentrum.uni-wuerzburg.de/…
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Get an opportunity to hear about transcription and gene regulation by one of the pioneers, Prof. Patrick Cramer @CramerLab @mpi_bpc in his talk at #Eureka2020 Check his research: mpibpc.mpg.de/cramer Have a look at #Eureka2020 speakers tinyurl.com/y26ldbah
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Great news! Our latest application for funding just got accepted by the DFG @dfg_public 🥳 Thanks for supporting our research in #ColorectalCancer!
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Die #CoronaWarnApp ist erfolgreich gestartet. Die #App wird mit jedem Nutzer nützlicher, es ist deshalb wichtig, dass so viele wie möglich mitmachen. Infos zur Corona-Warn-App auf rki.de/covid-19-warnapp Hier der aktuelle Stand der Download-Zahlen:
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WiegeringLab retweeted
DKFZ@DKFZ18 Jun 2020
Versicherte nutzen den Test zur #Darmkrebsfrüherkennung dreimal häufiger, wenn sie den Test per Post erhalten und zurückschicken können. Das zeigte eine Studie von Wissenschaftlern des DKFZ gemeinsam mit @AOKBWPresse, @hausaerzteverb und @MEDIVERBUND BaWü bit.ly/2UT9hNO
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Review | The authors from @Uni_WUE outline the mechanisms that lead to deregulated mRNA translation in #ColorectalCancer. ✔️ Open access bit.ly/3diXxLx
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