@WagleLab

Wagle Lab @danafarber @broadinstitute

 Boston, MA
Joined March 2017
  • Tweets38
  • Following376
  • Followers198
4Media
Great teamwork. Thanks @ZheqiL @Adrianvlee @npriedig @Vignali_Lab @BcellBruno @JenRicher3 @benhopark @nilguntasdemir1 @amir_bahreini @Kai__Ding @MCristofanill @GertzLab @simakali1 @WagleLab Now the more challenging task - move findings to the clinic! #bcsm
UPMC Hillman Cancer Center@UPMCHillmanCC12 May 2022
Dr. Steffi Oesterreich @oesterreichs featured in @NewsMedical about her latest research on a gene mutation found in 20-30% of #breastcancer recurrences and potential new opportunities for targeting these tumors. @UPMCnews @UPMCPhysicianEd news-medical.net/news/202205…

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

In this interview, we speak to Steffi Oesterreich, PH.D., from the University of Pittsburgh, about how new insights into a gene mutation present in 20-30% of breast cancer recurrences may have a...

news-medical.net
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Watching the #AACR21 session on sequencing metastatic #breastcancer? ICYMI in @CD_AACR: The genomic landscape of intrinsic and acquired resistance to CDK4/6 inhibitors in patients with HR+ metastatic #BreastCancer @Nikhilwagle @danafarber @broadinstitute cancerdiscovery.aacrjournals…
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At #ASCO21 today–need to bring #clinicaltrials closer to patients to encourage participation & promote integration of molecular data, especially relevant for rare cancers. Here's a great case of patient-partnership to accelerate research in angiosarcoma nature.com/articles/s41591-0…
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"Why is it important that breast cancer research include more Black women? Why have these patients been so understudied?" @Nikhilwagle answers this and talks about his new research focused on #MBC in Black women in this @BCRFcure blog.
The Breast Cancer Research Foundation@BCRFcure10 Jul 2021
We recently spoke with @Nikhilwagle about his research on metastatic breast cancer in Black women. Read the wide-ranging interview on our blog. bit.ly/3ysj0f7
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We recently spoke with @Nikhilwagle about his research on metastatic breast cancer in Black women. Read the wide-ranging interview on our blog. bit.ly/3ysj0f7
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Network-based mathematical models contribute to overcoming the challenge of cancer #DrugResistance. Tejeda Zañudo et al develop a model to identify drug combinations with PI3Kα inhibitors for ER+ PIK3CA mutant breast cancer. bit.ly/3kJwO1b @jgtzanudo @nikhilwagle
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The Metastatic Breast Cancer Project (@MBC_Project) is available in Spanish. Spanish-speaking metastatic breast cancer patients can now enroll in this patient-partnered research initiative. dana-farber.org/newsroom/new…
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The Metastatic Breast Cancer Project (MBCproject.org) has now been fully translated into Spanish, including the wesbsite, consent form, & all project materials — part of our ongoing efforts to make all @count_me_in research projects more inclusive & representative
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Today, our lab is participating in #StrikeForBlackLives #ShutDownSTEM. We’re pausing usual research activities & meetings - taking the day to listen, learn, & reflect on causes of systemic racism, anti-black bias, & long-standing inequities in research, healthcare & academia.
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In addition to listening & learning today, we’re working on concrete & sustained actions we can take in our lab to confront racism & be more inclusive - and we’re committed to this work as long as necessary. #StrikeForBlackLives #ShutDownSTEM #ShutDownAcademia #BlackLivesMatter
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Please find more details about the day and additional resources here: shutdownstem.com/ particlesforjustice.org/ #StrikeForBlackLives #ShutDownSTEM #ShutDownAcademia #BlackLivesMatter
Our annual lab holiday party, celebrating the end of a great and productive year. I am so lucky and grateful to have this incredible group of people to work with. Happy holidays! @WagleLab @count_me_in
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Role of AKT mutations in mediating resistance to endocrine therapy and CDK 4/6i in MBC. Nice work led by Dr. Seth Wander ⁦@MGHCancerCenter⁩ and collaboration with ⁦@Nikhilwagle⁩. Implications for treatment in post CDK 4/6 setting.
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Over 4 years, we collected 500+ metastatic biopsies from 446 patients w MBC. Characterization includes whole exome sequencing (~20,000 genes), RNA-seq, and other genomic and molecular tests #SABCS19
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Over the past several yrs, we‘ve had a program to collect & deeply characterize metastatic biopsies from @DanaFarber patients with MBC (working w Nancy Lin, @DrEricWiner, DFCI breast oncology colleagues, DFCI/BWH Center for Cancer Precision Med, & many others) #SABCS19
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Quick recap of Ofir Cohen’s presentation “Acquired activating mutations in RTKs confer endocrine resistance in ER+ metastatic breast cancer through ER-reprogramming, MAPK signaling, and an induced stem-like cell state” in #SABCS19 General Session 2 earlier today
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#ASCO18 lab dinner @duckduckgoatchi (Forgot to get a pic of the whole crew!)
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Thank you so much @Nikhilwagle for your mentorship and congrats to all my #labmates @WagleLab @DanaFarber #Immunotherapy #mbc xitter.cf/nikhilwagle/status/100… – at Chicago, IL
Nikhil Wagle, MD (he/him)@Nikhilwagle5 Jun 2018
A particular highlight for me this year was the privilege of watching the successes of the junior investigators in my lab. Could not be more proud. Congrats Ada, Seth, Romualdo, Esha, Ofir, Ana! @WagleLab #ASCO18
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A particular highlight for me this year was the privilege of watching the successes of the junior investigators in my lab. Could not be more proud. Congrats Ada, Seth, Romualdo, Esha, Ofir, Ana! @WagleLab #ASCO18
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What a fantastic #ASCO18! Congrats to @ASCOPres @YoungStrongDFCI @CliffordHudis & @ASCO organizers on great conference. Wonderful to see so many friends, colleagues, patients, advocates, mentors. Feeling energized & inspired by all - looking forward to our continued work together
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