@Titz_Lab

Nature enthusiast, Professor of Chemistry/Saarland Uni and group lead at HIPS, wheelchair-bound. Views are my own. https://xitter.cf/t.co/N8qWTGOTBL

 Saarland, Germany
helmholtz-hips.de
Joined November 2017
  • Tweets1.2K
  • Following1.1K
  • Followers1.1K
90Media
Seems like this place gets stranger and stranger. Chemtwitter is mute and most of my new followers are bots 🙄 See you at the other side 🦋 bsky.app/profile/titzlab.bsk…
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Alexander Titz retweeted
Anja Reschke@AnjaReschke120 Dec 2024
Hey @elonmusk - stay out of it - it's not your business It's our country - You have absolutely no idea - if anyone is an expert on fascism, it's us - shuffle off and go play with your rockets.
Elon Musk
@elonmusk20 Dec 2024
Only the AfD can save Germany
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I am very proud to share a long story on lectins and biofilm imaging just published in @JACS_Au by Eva and Lisa in cooperation with many colleagues such as @AnneImberty @SueSK001 😍 #glycotime #chembio #AMR please have a look here: pubs.acs.org/doi/10.1021/jac…

High-Affinity Lectin Ligands Enable the Detection of Pathogenic Pseudomonas aeruginosa Biofilms:...

Abstract. Pseudomonas aeruginosa is a critical priority pathogen and causes life-threatening acute and biofilm-associated chronic infections. The choice of

pubs.acs.org
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Thank you @Dhritirajbastav for the vivid discussion after my talk and at your poster in Amritsar! Good luck with all your enzymology experiments!
DHRITIRAJ BASTAVKALITA@Dhritirajbastav15 Nov 2024
Blessed with your inspiring words dear prof @Titz_Lab . Had a nice time meeting you.
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Participants of the Indo-German Meeting #ECBS-2024 at Le Meridien Amritsar, coinciding with 50 years India and Germany S&T cooperation. Anticipating complex multidisciplinary science, involved interactions and useful collaborations. @INDOGSTC @GermanyinIndia
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It was a great honor for me to kick off the scientific sessions of this great meeting! Big thanks to @Sandeep_1966 and the organizers! #ECBS #Amritsar
Sandeep Verma (स्वर)@Sandeep_196613 Nov 2024
Replying to @Sandeep_1966
Perfect kick-off for the Indo-German #ECBS-2024 by Prof Alexander Titz @Titz_Lab on new approaches for antibiotic discovery. Scintillating lecture! More excitement and lectures continue.
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Glycotime in infection 😍
ZackB
@zacharyberndsen10 Oct 2024
Our new paper describing the structure, function, and antigenicity of the Blood Group A-specific lectin, EtpA, from ETEC is out in #PLOSPathogens dx.plos.org/10.1371/journal.… Tons of exciting #glycotime results!

Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic...

Author summary Enterotoxigenic E. coli (ETEC), a leading cause of diarrhea disproportionately affecting young children in low-income regions, are a priority for vaccine development. Individuals...

journals.plos.org
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Proud to share our work on a novel, cool lectin from Enterobacter cloacae 😍! Unique structure and unique ligand binding specs! Might be a novel target. Check it out and enjoy reading. @Helmholtz_HIPS @Saar_Uni @DZIF_
bioRxiv Microbiology@biorxiv_micrbio2 Oct 2024
A fucose-binding superlectin from Enterobacter cloacae with high Lewis and ABO blood group antigen specificity biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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Great teamwork by @Ghamdanb Asfandyar Julia Roman Steffi @Schramicks @JeskoKoehnke
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We are still struggling to find out the LecA domain ligand....
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In a joint project with @HirschLab we have developed molecules that block two bacterial virulence factors in Pseudomonas infections. The new compounds were superior over combinations of single LecA and LasB blockers. #AMR #glycotime now in @ChemicalScience pubs.rsc.org/en/Content/Arti…

Dual inhibitors of Pseudomonas aeruginosa virulence factors LecA and LasB†

Dual inhibitors of two key virulence factors of Pseudomonas aeruginosa, the lectin LecA and the protease LasB, open up an opportunity in the current antimi

pubs.rsc.org
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We were having an amazing time, discussing science and meeting friends at ICS2024 thanks to Prof. Biao Yu 🥰 On top, Qiuyu won the poster prize 👍
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AlphaFold2 and RoseTTAFold are limited to predicting the 3D structure of proteins. A new all-atom method models complete biomolecular assemblies, including proteins, nucleic acids, small molecules, metals, and covalent modifications. #NBThighlight science.org/doi/10.1126/scie…

Generalized biomolecular modeling and design with RoseTTAFold All-Atom

Deep-learning methods have revolutionized protein structure prediction and design but are presently limited to protein-only systems. We describe RoseTTAFold All-Atom (RFAA), which combines a residu...

science.org
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The antibiotic drug candidate Zosurabalpine, belongs to a new family of antibiotics. On mice studies it showed effectiveness against Acinetobacter baumannii pneumonia (a very problematic and resistant bacteria). nature.com/articles/d41586-0… @SeeFisch dlvr.it/T2wktK

A new class of antibiotics is cause for cautious celebration — but the economics must be fixed

Nature - The threat of antimicrobial resistance means that new antibiotics need to be used sparingly. Governments must support their development with a long-term funding plan.

nature.com
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Leifichemie ist eine tolle Plattform allen Schülern und Schülerinnen die Chemie anschaulich und interessant näher zu bringen! Highly recommended!! 🤩 leifichemie.de
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Alexander Titz retweeted
Glenn Facey@uOttawaNMR18 Feb 2024
I have less than 1 mg of sample. How can I get an NMR spectrum with a higher signal-to-noise ratio? u-of-o-nmr-facility.blogspot… #nmrchat
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Needless to say that this is a carbohydrate powerhouse #glycotime
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Rob and I had a cool city tour in Utrecht today and a random 'talented' photographer 🤣 thanks, @RobertPdeVries1 for the science/history tour!
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✨We are happy to share our final publication of 2023! ✨ A comprehensive review in @npjAMR on how to tackle the Gram negative outer membrane to increase #antibiotic efficacy from @skchopra007 @Titz_Lab @Sandeep_1966 and colleagues💊 nature.com/articles/s44259-0… (1/6)

Tackling the outer membrane: facilitating compound entry into Gram-negative bacterial pathogens

npj Antimicrobials and Resistance - Tackling the outer membrane: facilitating compound entry into Gram-negative bacterial pathogens

nature.com
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