The Melton Lab retweeted
Looking forward to keynote talks from @HansClevers, @TheMeltonLab & @GVNlab @CellSymposia #CSStemCells22 #stemcells #LosAngeles #California @CedarsSinaiMed December 8–10, 2022 Register here hubs.li/Q01rNvCk0
The Melton Lab retweeted
G. Oliver @NU_Lymphatics (🇺🇸@NUFeinbergMed), C. Blanpain @CedricBlanpain (🇧🇪@ULBruxelles) & D. Melton @TheMeltonLab (🇺🇸@harvardstemcell) are the guest speakers in the #ISDB2021 session “𝗙𝗿𝗼𝗺 𝗱𝗲𝘃𝗲𝗹𝗼𝗽𝗺𝗲𝗻𝘁 𝘁𝗼 𝗱𝗶𝘀𝗲𝗮𝘀𝗲”
Join us in 🇵🇹👉 ISDB2021.com/registration
The Melton Lab retweeted
Using a CRISPR screen and single cell analyses we asked how do stem cell-derived islets (SC-islets) react to immunological pressure (allogeneic). Among the hits we identified CXCL10 depletion as a way to escape immune rejection of grafted #betacells.
cell.com/stem-cell-reports/f…
The Melton Lab retweeted
Take a look at the speaker line-up for #CSStemCells22, including keynotes @HansClevers, @TheMeltonLab & @GVNlab #stemcells #LosAngeles #California @CedarsSinaiMed hubs.li/Q01d-_NX0
The Melton Lab retweeted
Couldn’t ask for a better closure for my postdoc era. Was so great to attend and present at #ISSCR2022! Met so many old and new friends/colleagues. Some of which you see only in meetings like these every few years. Hope to see you all next year in Boston #ISSCR2023 @ISSCR
The Melton Lab retweeted
Cell maturation: Hallmarks, triggers, and manipulation
@TheMeltonLab @Harvard @JuanAlvarezDom @PennCDB @IRM_Upenn @CellCellPress #ISSCR2022 hubs.li/Q01dFNRR0
The Melton Lab retweeted
Tomorrow 6/16 at #ISSCR2022, excited to present 'Immunogenicity of stem-cell derived islets as defined be a whole-genome CRISPR screen'. In person or virtual.
1:45pm PDT/4:45pm EDT, at 'Stem Cell Bioengineering - enhancing cell function'.
The Melton Lab retweeted
Happy to share a pre-print of some work from my time in the @TheMeltonLab. First and foremost, many thanks to all the co-authors involved!! Now, for a brief outline of the findings..
Secreted cytokines provide local immune tolerance for human stem cell-derived islets biorxiv.org/cgi/content/shor… #bioRxiv
Check out our latest pre-print entitled “Whole Genome CRISPR Screening of Stem Cell Derived Islets Reveals Gene Targets for Hypo-Immunogenicity”
Glad and excited to share our online pre-print of a paper submitted for peer review in @CellStemCell. We report a whole genome CRISPR screen and transcriptomic profiling of immune challenged stem cell derived islet cells. See thread below
ssrn.com/abstract=4081520
The Melton Lab retweeted
I’ve finally settled back home in Sydney, Australia with my family. I’d like to thank Doug and all my colleagues in the @TheMeltonLab for the wonderful years together. Hope to see you soon Down Under!
The Melton Lab retweeted
This is just one of many good things that might happen when you listen to the Stem Cell Report. Hear more from Doug Melton @TheMeltonLab & @naleite at bit.ly/3rqVhea & read their recent paper, bit.ly/3EkcXxp. @harvardstemcell @VertexPharma @ISSCR @martinperaJAX
The Melton Lab retweeted
⏰ Don't miss the opportunity to hear groundbreaking research & to network with this impressive line-up of past #ISSCR presidents at the #ISSCR2022 Annual Meeting 15-18 June in San Francisco. Register by 11:59 EDT 13 April for the best rates 👉 ow.ly/oLJM50IJcqW
The Melton Lab retweeted
Probably the last time together with these outstanding people and outstanding mentor. Thank you @TheMeltonLab
The Melton Lab retweeted
It was a pleasure to participate with @TheMeltonLab on the @stemcellreports podcast. Thank you for having me!
👏 Our new podcast is out! Learn about the latest research & potential clinical approaches using #stemcell-based treatments for type 1 #diabetes. 🎧 ow.ly/Xe6m50IxJlU Read 👉 bit.ly/3J1nCxI @martinperaJAX @TheMeltonLab @harvardstemcell @naleite @VertexPharma
The Melton Lab retweeted
👨🔬Hear abt Doug Melton's latest work developing #stemcell therapies for #diabetes @ our Jerusalem symposium. His pioneering work deriving insulin-producing beta islets cells from PSCs led to the 1st in-human clinical trial ow.ly/7FAe50Im00X
@HSCRB @harvardstemcell @Harvard
The Melton Lab retweeted
🔬Today in @stemcellreports, research from @naleite, Douglas Melton & colleagues has identified new ways to enhance the SC-beta cell survivability through genetic manipulation of the cells. Read on 👉 bit.ly/3CeeAeR. Image: The Foundry. @martinperaJAX @TheMeltonLab
The Melton Lab retweeted
Diabetes cell therapies take evasive action - @ElieDolgin go.nature.com/3hn0P42
The Melton Lab retweeted
“The promising results we’ve seen with #stemcell-derived islet cells could deliver a life-changing therapy for people who suffer from the relentless life-long burden of #Type1diabetes," said Dr. Douglas Melton, co-director of @harvardstemcell Institute.
Sheikh Mohamed bin Zayed, Crown Prince of Abu Dhabi, provides grant to Harvard Stem Cell Institute for diabetes research thenationalnews.com/uae/scie…
“Meet the Scientist: Douglas Melton” on vimeo.com/442134935/9f56d698… special thanks to @JDRF and @TheMeltonLab team! @HSCRB
The Melton Lab retweeted
Are your cells mature? Does it matter? In our latest @CellCellPress, we review Cell maturation: Hallmarks, triggers, and manipulation. We discuss a new framework, based on cell plasticity, to understand how cells become specialized.. @PennCDB @IRM_UPenn
authors.elsevier.com/c/1eNDX…




























