@TCrispr

CRISPR videos by CRISPR scientists

youtube.com/c/TalkingCRISPR
Joined June 2018
  • Tweets116
  • Following33
  • Followers548
40Media
Phages in babies protect kids from disease half a decade in the future! Full text on @NatureMedicine : rdcu.be/dtGTc #phage #CRISPR #virome @Jonathanthdk @smoineau @stokholm_jakob @JPI_HDHL @novonordiskfond @COPSAC_com
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Huge congrats to @cristinalero for driving this one home!
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The baby #phage #asthma story is on the front page of politiken.dk now
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Phages in babies protect against future disease! Check out our latest paper in @NatureMedicine nature.com/articles/s41591-0… @COPSAC_com
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Alright, admitted, I was intimidated by twitter's name change, and haven't been online before now. But since then, this happened!!! Big congrats to @SarahCamara94 #dav604 and @rafapinilla92 uncovering these unbelievable RNA based anti-#CRISPR s
nature
@Nature18 Oct 2023
Nature research paper: Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs go.nature.com/3QmVDPY

Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs

Nature - In response to bacterial CRISPR–Cas immunity, phages and plasmids have evolved small non-coding RNA anti-CRISPRs, known as Racrs, that sequester Cas proteins in abberrant complexes...

nature.com
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Such a pleasure talking with @JacquesHughes about our findings. Big thanks to the @NaturePodcast team for having me! Tune in to the episode to hear our conversation🦠🎙️ nature.com/articles/d41586-0…
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Dr. Evelien Adriaenssens wrote this beautiful opinion piece about our recent baby virus study. She is the chair of the bacteriophage subcommittee within the ICTV, so her opinion matters. And I'm humbled to say the least. @COPSAC_com @JPI_HDHL #phage
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MindBlow on @VsauceTwo is featuring our infant gut virome story (skip to 0:39) 🤓😃😎 youtu.be/sxi0-Y_RWsU?t=39 #virome #omics #YouTube @JPI_HDHL @COPSAC_com @NatureMicrobiol @novonordiskfond

Why Bugs Are Attracted To Light SOLVED - Mind Blow

Use code VSAUCE250 to get 50% off your first Factor box at https://...

youtube.com
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Nice coverage on our infant virome story! @COPSAC_com @JPI_HDHL @washingtonpost @novonordiskfond @NatureMicrobiol washingtonpost.com/health/20…

Scientists identify thousands of unknown viruses in babies’ diapers

Research involving Danish babies has yielded a great deal about previously unknown viruses — and the best view yet of the makeup of the infant gut microbiome.

washingtonpost.com
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Now also on @WebMD: webmd.com/children/news/2023…

Milestones for Your Baby's First Year

Curious what to expect from your baby's first year? WebMD teaches you all the major milestones to look out for from newborn to 12 months.

webmd.com
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New database of 10.000 infant gut phages to map your baby reads against: copsac.com/earlyvir/f1y/fig1… copsac.com/earlyvir/f1y/taxt… copsac.com/earlyvir/f1y/all.… @JPI_HDHL @COPSAC_com @novonordiskfond #omics #phage #virome
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Looks like phage diversity is higher in babies than adults. Why? Check out the story behind the paper. It's a four-minute read. microbiologycommunity.nature… @COPSAC_com @JPI_HDHL @NatureMicrobiol #phage #CRISPR #virome @cristinalero @smoineau @stokholm_jakob @GormAnders @microUCPH
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We found hundreds of viral families in baby diapers. Everything we found is online (copsac.com/earlyvir/f1y/fig1…). This project started all the way back in 2016. So excited that it's finally out! @COPSAC_com @JPI_HDHL #OpenScience #phage #CRISPR #virome #metagenome
Nature Microbiology@NatureMicrobiol11 Apr 2023
Out now: Expanding known viral diversity in the healthy infant gut By Shiraz Shah, Ling Deng, Dennis Nielsen & colleagues. @tcrispr @COPSAC_com nature.com/articles/s41564-0…

Expanding known viral diversity in the healthy infant gut

Nature Microbiology - Faecal viromes of 647 healthy infants were deeply sequenced to identify more than 230 previously undescribed gut virus families, expanding known diversity within the human...

nature.com
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Talking CRISPR retweeted
Gisle Vestergaard@gisleDK13 Apr 2023
Replying to @TCrispr
@TCrispr lays out his brilliant paper on phages in childrens gut. I remember once thinking "Wow, we identified a handful of new viral families!". Shiraz and the rest of this group just found +100 new ones 🤯 Check out the brilliant online overview 👇 tiny.cc/aq76vz
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The guts of healthy infants are alive with viral diversity @COPSAC_com @NatureMicrobiol nature.com/articles/s41564-0… #phage #CRISPR #microbiome #virus

Expanding known viral diversity in the healthy infant gut

Nature Microbiology - Faecal viromes of 647 healthy infants were deeply sequenced to identify more than 230 previously undescribed gut virus families, expanding known diversity within the human...

nature.com
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1/n Excited to share a story on prokaryotic Argonautes (pAgos)!! 🎉 Here, we describe a short pAgo that mediates robust antiviral protection!🛡️ But how!? 🧵👇 biorxiv.org/content/10.1101/…

A short prokaryotic argonaute cooperates with membrane effector to confer antiviral defense

Argonaute (Ago) proteins are widespread nucleic acid-guided enzymes that recognize targets through complementary base pairing. While in eukaryotes Agos are involved in RNA silencing, the functions of...

biorxiv.org
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Another defence system, guys: biorxiv.org/content/10.1101/… The prokaryotic argonaute recognises viruses using a guide RNA, then activates a transmembrane protein to depolarise the membrain and commit suicide. #antiviral #antiphage #archaea #CRISPR
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Very excited to see our story online in @NAR_Open!🎉 We found plasmids in nature carry a fascinating diversity of CRISPR-Cas🌈🤯 We characterized their abundance, diversity, distribution & investigated their CRISPR contents to infer their function(s)!! academic.oup.com/nar/advance…

CRISPR-Cas systems are widespread accessory elements across bacterial and archaeal plasmids

Abstract. Many prokaryotes encode CRISPR-Cas systems as immune protection against mobile genetic elements (MGEs), yet a number of MGEs also harbor CRISPR-C

academic.oup.com
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Talking CRISPR retweeted
Simon Rasmussen@simonrasmu9 Jul 2021
Binning #viral / #phage genomes directly from #metagenomics data while automatically defining #viralpopulations across samples? Now you can using PHAMB - new tool to run on top of VAMB (or another binner)! Fantastic work led by @joachim from my group: biorxiv.org/content/10.1101/…

Genome binning of viral entities from bulk metagenomics data

Despite the accelerating number of uncultivated virus sequences discovered in metagenomics and their apparent importance for health and disease, the human gut virome and its interactions with...

biorxiv.org
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