Understanding and developing therapy for the treatment of patients with hematologic disorders.
Boston, MA
Joined October 2017
- Tweets25
- Following90
- Followers236
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SykesLabMGH retweeted
We're thrilled to introduce our next challenger of #BreakItDownForMe, David Sykes, MD, PhD!
Watch a sneak peek below to learn what he does when he isn't breaking down his [very complex] paper for us!
Watch the complete video: mgriblog.org/2023/04/03/brea…
@SykesLabMGH
A huge team effort done in collaboration with friends at Karolinska Institute where we explored the underpinnings of metastatic renal cell carcinoma. advances.massgeneral.org/uro….
Please join me, along with my colleagues at the Mass General Cancer, at the upcoming Mass General Cancer Center Classical Hematology Review & ASH Highlights virtual CME on February 14-15. To view the agenda and enroll, click here: shorturl.at/tNUXY.
SykesLabMGH retweeted
Check out our new paper on combined targeting of de novo and salvage pyrimidine nucleotide synthesis for cancer treatment. This strategy dramatically improved survival in a highly aggressive, immunocompetent mouse model of PDAC.
doi.org/10.1016/j.canlet.202…
SykesLabMGH retweeted
There needs to be a Red Zone equivalent for college football. They can just call it “Degeneracy”
SykesLabMGH retweeted
Our latest is now @NatureComms! From OR➡️lab, we studied potential therapeutic targets at the molecular level using single-cell analysis of tumor cells from the kidney & spine. Go team! @baryawno @SykesLabMGH @ScaddenLab @KharchenkoLab @MGHNeurosurg
rdcu.be/cWLDN
Hiring! Looking for a postdoctoral researcher. Project involving solid tumor bone marrow metastases. hematopia.com/sykes-lab
SykesLabMGH retweeted
Exciting new paper from the lab showing the impact of neutrophil precursors as a cellular therapy for invasive fungal infection in neutropenia.
pubmed.ncbi.nlm.nih.gov/3535…
Our cover image for this JLB issue:
ALT Scanning EM of an engineered neutrophil engaging with Candida albicans
A very nice paper that marries cool chemistry and real biology from friend and colleague (last author) Jonathan Carlson. nature.com/articles/s41587-0…
SykesLabMGH retweeted
Today we're working with the Hoxb8 cells (immortalized myeloid progenitors that can be differentiated into neutrophils). Our PhD student @juls_sala is applying lentivirus CRISPR/Cas9 to Hoxb8 cells to study the functional regulators of neutrophil maturation and effector functions
#Hiring #research #Laboratory
Looking for research technicians to join our lab at the Massachusetts General Hospital!
hematopia.com/sykes-lab
#Hiring | Looking for curious scientists who can spend 2+ years with us as research technicians working on rare disorders of the bone marrow! | sykeslab.com/join/
SykesLabMGH retweeted
Excited to share our study of a patient with aplastic anemia, where a genetic diagnosis led to a successful targeted intervention, and new avenues of promising biology cell.com/med/fulltext/S2666-… @MedCellPress.
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SykesLabMGH retweeted
The Sykes Lab is hoping to hire a research technician and post-doctoral fellow. Please check us out sykeslab.com/join/ if you are interested!
SykesLabMGH retweeted
David Sykes MD PhD @SykesLabMGH @MassGeneralNews studies TEMPI characterized by Telangiectasias, ⬆️ Erythrocytosis, Monoclonal gammopathy, Perinephric fluid, Intrapulmonary shunting -> finds effective therapy. @ASH_hematology @katrinarmstrong bit.ly/2Qwu4Yi
SykesLabMGH retweeted
To prepare for future pandemics we must support physician-scientists | @thehill many thanks @jennkwanMDPhD @DrEJBMD for the nice mention thehill.com/opinion/healthca…
The Sykes Lab is hoping to hire a research technician and post-doctoral fellow. Please check us out sykeslab.com/join/ if you are interested!
Are you interested in blood, and developing treatments for leukemia? We are looking for creative and talented postdoctoral scientists to join our lab at the Massachusetts General Hospital in 2018. sykeslab.com/join/