The Mansour Lab at MGH focuses on developing novel cellular diagnostics and therapies for invasive fungal infections. Affiliated with HMS and CIG.
Joined May 2020
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Dr. Amir Arastehfar presenting his research at IDWeek 2023: The Clinical Implications of High Echinocandin Persistence of a Major Fungal Pathogen and Development of a Rapid and Convenient Approach to Determine Echinocandin Persistence
Farnaz Daneshnia presenting her research at IDWeek 2023: Biofilm and Aggregate Formation as an Efficient Strategy Used by C. parapsilosis to Persist Echinocandin Treatment and Evade the Innate Immune Cells
Dr. Anna Apostolopoulou presenting at IDWeek 2023: A man in his fifties with a 2-month history of a swollen and tender calf
Emma Yvanovich presenting her research at IDWeek 2023: Using CRISPR/Cas9 to dissect the regions of MLL/AF9 that are critical for myeloid immortalization
Kyle Timmer presenting his research at IDWeek 2023: Optimized hematopoietic stem cell source for the ex vivo production of mature human neutrophils as a potential cell-based therapy for neutropenia
Nathan Jeffries presenting his research at IDWeek 2023: A Focused Screen Identifies Essential Genes Enabling Increased Expansion in Hematopoietic Stem Cells to Generate Human Neutrophils
Daniel Floyd presenting his research at IDWeek 2023: Human Mesenchymal Stem Cells Augment Neutrophil Function to the Human Fungal Pathogen, Candida albicans
Dr. Johnny Atallah presenting his research at IDWeek 2023 on CT-ProET-1 and sFlt-1 as predictors of clinical outcomes in COVID-19
Congratulations to Johnny for being one of the final winners at the annual MGH Scientific Advisory Committee meeting for his work on host transcriptional profiling in patients with fever
The Mansour Lab retweeted
Learn more from Dr. Michael Mansour @MKMansour_MDPhD during his talks at #IDinAdults2023.
The deadline to receive the early registration discount is only NINE DAYS away!
✅id.hmscme.com
CDC warns cases of dangerous fungus rising quickly in U.S. @LouisaMoller reports cbsnews.com/boston/news/cdc-…
An amazing study by Kyle Timmer exploring a new multiparametric assay capable of determining several key neutrophil functional responses at once! Nice job Kyle!
Congratulations to Johnny Atallah for his new publication looking at transcriptional signatures in patients presenting with fever to the emergency department!
The Mansour Lab was thrilled to speak at 3 sessions during ID Week 2022 in Washington DC last week. Fantastic presentations by Dr. Michael Mansour, Dr. Johnny Atallah, and Vahe Panossian on their research of procalcitonin and MR-proADM. #IDWeek2022
The Mansour Lab retweeted
@Mansour_Lab
Fantastic work by Adam Viens from the lab showing Syk-independent accessory pathway responsible for neutrophil responses to Candida
Great work, Adam!
TLR Signaling Rescues Fungicidal Activity in Syk-Deficient Neutrophils.
Viens AL et al. J Immunol. 2022 Apr 1.
Exciting new paper from the lab showing the impact of neutrophil precursors as a cellular therapy for invasive fungal infection in neutropenia.
pubmed.ncbi.nlm.nih.gov/3535…
Our cover image for this JLB issue:
ALT Scanning EM of an engineered neutrophil engaging with Candida albicans
New paper from @NicoBarrosID and @NatJAlexander shows neutrophil dysfunction in transplant patients can be reversed by GCSF!
Cytokine Augmentation Reverses Transplant Recipient Neutrophil Dysfunction against the human fungal pathogen, Candi… pubmed.ncbi.nlm.nih.gov/3341…
