@StevenWade98
 Ottawa, Ontario
Joined April 2020
  • Tweets98
  • Following410
  • Followers170
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Had such a great time presenting my work at the @OISB_IBSO-@NRC_CNRC Trainee Research Day! Huge thank you to the organizers for this fantastic opportunity. And of course a big thank you to my supervisor @MireilleKhacho and all members of the @KhachoLab!
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Steven Wade retweeted
Lowe Lab@LoweLabMSKCC11 Jul 2025
Excited to share our latest work out now in print @Nature! Lead by @almudena_Chaves and @ScottMillman_MD, we uncover how metabolic rewiring via OGDH controls tissue regeneration and stem cell fate in the intestine 🚀🚨 bit.ly/44oaOiW
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Congratulation @liv_sommers !! So well deserved!
Khacho Lab@KhachoLab16 Apr 2025
🎉 Congratulations to @liv_sommers for successfully defending her Master’s Thesis in Biochemistry on April 11, 2025! You did a fantastic job and we’re all so proud of you! 🔬🧠👏 #MastersDefense #Biochemistry #WomenInSTEM 🧪✨
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Khacho Lab@KhachoLab19 Mar 2025
Huge congratulations to Rholls @RTomsine for being a recipient of the 2025 OISB-NRC Graduate Scholarship Award! 🎉👏 Excited to see all the amazing things ahead! #Proud #Scholarship #Congrats
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Artem Khan@ArtemAKhan20 Feb 2025
Excited to share our perspective on solute carrier transporters - gatekeepers of metabolism sciencedirect.com/science/ar… @KivancBirsoy @YuyangLiu1996 @gadmark @TimCKenny @CellCellPress @RockefellerUniv
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Dual regulation of mitochondrial fusion by Parkin–PINK1 and OMA1 nature.com/articles/s41586-0…

Dual regulation of mitochondrial fusion by Parkin–PINK1 and OMA1

Nature - We find that, in mice, although the individual loss of Parkin or OMA1 does not affect mitochondrial integrity, their combined loss results in small body size, low locomotor activity,...

nature.com
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Congratulations @MireilleKhacho !! 🎉
OISB@OISB_IBSO15 Oct 2024
Congrats to @MireilleKhacho from @OISB_IBSO for award for Early Career Researcher of the Year from the Faculty of Medicine!
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PINK1 deficiency alters muscle stem cell fate decision and muscle regenerative capacity: Stem Cell Reports cell.com/stem-cell-reports/f…

PINK1 deficiency alters muscle stem cell fate decision and muscle regenerative capacity

Maintenance of mitochondrial function plays a crucial role in muscle stem cells (MuSCs) fate decision, but the underlying mechanisms remain ill-defined. Here, Cairns and colleagues examined the role...

cell.com
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Steven Wade retweeted
FrezzaLab@FrezzaLab28 Mar 2024
Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis | Science science.org/doi/10.1126/scie… congrats to @bensahralab!!! whoa!

Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis

Evidence for UTP as a phosphate donor for thiamine pyrophosphate formation is found.

science.org
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Join us this month as we welcome Dr. Mireille Khacho from @uOttawa. 🌟 She'll be sharing insights on "Mitochondria direct muscle stem cell fate and muscle regeneration." Save the date: March 25th, 2-3pm EST. #ScienceTwitter #MuscleRegeneration @MireilleKhacho @KhachoLab
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Happy to share our new work showing the importance of OPA1 and mitochondrial remodelling at the onset of muscle differentiation. OPA1, together with SCAF1, mediate the metabolic switch that is essential for differentiation. cell.com/iscience/pdf/S2589-… @uOttawaBMI @OISB_IBSO
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Steven Wade retweeted
OISB@OISB_IBSO28 Nov 2023
Congrats to @MireilleKhacho on her appointment as the new Director of the Metabolomics Core Facility @OISB_IBSO!
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Had an amazing time presenting my work @CSMB2023 in the metabolomics section today! Such great presentations so far! Thank you @CSMB_SCBM for the opportunity and to my supervisor @MireilleKhacho for her support!
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Had such an amazing time presenting my work at the @uOttawaBMRI Stem Cell Research Day! Thank you to my supervisor @MireilleKhacho and all members of the @KhachoLab for making this possible!
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Wood frogs use freeze tolerance to survive subzero temps. Wade et al. found that despite stable levels of mRNA methylation during freezing and anoxia, abundance of m6A methyltransferases increased. So m6A methylation might coordinate freeze-thaw cycles bit.ly/3AAN77l
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Online Now! Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging dlvr.it/SmlBNf #stemcells

Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian...

Liu et al. generate a transcriptomic single-cell atlas of skeletal muscle, neural and hematopoietic stem cells, and their niche environment and progeny during aging and in response to exercise....

cell.com
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📢 We are happy to announce that our latest collaborative work led by @Paarime and @narbonaperez is published now in @CellReports 💡 The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage 🧵 Thread (1/7) cell.com/cell-reports/fullte…
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Online Now: Determinants and outcomes of mitochondrial dynamics dlvr.it/SkW0Yf

Determinants and outcomes of mitochondrial dynamics

Quintana-Cabrera and Scorrano review the molecular mechanisms regulating mitochondrial morphology and ultrastructure and discuss how they have an impact on mitochondrial physiology.

cell.com
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Steven Wade retweeted
Khacho Lab@KhachoLab23 Feb 2023
The newest publication from the Khacho Lab is out now in @STARProtocols ! Here, we outline steps for evaluating mitochondrial length, volume and cristae ultrastructure in rare mouse adult stem cell populations. star-protocols.cell.com/prot…
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