👩🏼⚕️Young medical doctor 🔥 Pancreatic researcher 💫 Running, cycling, skiing, fieldhockey
Joined August 2022
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🚨 Significant interrater variability in scoring the ASA classification for patients undergoing HPB surgery
📊 Survey 1283 surgeons/anaesthesiologists
🌎 55 countries
‼️ Additional guidance is needed, until then more objective measurements should be used for case-mix adjustment
Inter-rater variability for the American Society of Anesthesiologists classification in patients undergoing hepato-pancreato-biliary surgery (MILESTONE-2): international survey among surgeons and anaesthesiologists
➡️doi.org/10.1093/bjsopen/zrae…
This is an international survey and case-vignette study including 1283 participants from 55 countries. Interrater variability regarding the ASA classification in patients undergoing HPB surgery was observed, which may impact perioperative strategy. Additional guidance to classify patients according to ASA is urgently needed. Until then, more objective measurements should be considered for case-mix adjustment within research.
👏👏👏@Simone_Aug, Jasper P Sijberden, Matthanja Bieze, Vandana Agarwal, Luca A Aldrighetti, Adnan Alseidi, Francisco C Bonofiglio, Kevin C P Conlon, Katia Donadello, Joris Erdmann, Cristina Ferrone, Michael Guertin, Ronald Harter, Maria E Franceschetti, Guiseppe K Fusai, Bas Groot Koerkamp, Thilo Hackert, Jin-Young Jang, Thomas Kander, Tobias Keck, Dominik Krzanicki, Ho-Jin Lee, Keith Lewis, Giuseppe Natalini, Carla Nau, Timothy M Pawlik, Henry A Pitt, Rafaella Reineke, Roberto Salvia, Eduardo de Santibanes, Shailesh V Shrikhande, Martin Smith, Attila Szijarto, Bobby Tingstedt, Alice C Wei, John Windsor, @Abuhilal9Abu, Manuel Pardo, Markus W Hollmann, @MarcBesselink for the MILESTONE Study Group
#SoMe4Surgery #MedTwitter #SurgEd #Surgery @BJSAcademy @BJSurgery @young_bjs @juliomayol @JJEarnshaw @OUPMedicine #some4hpb #some4tpl @hpb_so #PancreaticCancer #PancreaticSurgery @YouppiePancreas @German_PancClub @surgery_hps #PancreasClub2023 @PancreasClub @DPCG_official @pancreatitis_nl @PanCAN #PanCANawareness @EurPancClub @P_C_E_ @dice_europe
In @JNCCN our nationwide study on quality of life in patients with locally advanced PDAC🇳🇱
⭐️QoL remains stable over time, regardless of receiving treatment (89%)
‼️Symptoms significantly deteriorate and deserve attention
➡️Use in shared decision making simoneaug.bsky.social
Full tekst: jnccn.org/configurable/conte…
Simone Augustinus retweeted
Only 10% of recommendations in surgical clinical practice guidelines are supported by high quality evidence. ja.ma/4hVd99L
Simone Augustinus retweeted
(Let’s keep using this social in the best possible way … ) 🫢
🟠 Recurrence after PDAC resection is sadly a fact
🔵 @EAHPBA study on 333 pts reveals routine imaging in post op 👍 vs. symptomatic FU
💡Prompt access chemo = better survival
jamanetwork.com/journals/jam…
Simone Augustinus retweeted
How big are the differences in the use, outcome Lap/Robot 🤖 #Whipple between 4 registries 🇺🇸/🇨🇦, 🇩🇪, 🇳🇱, 🇸🇪? #GAPASURG
▶️ Very large differences among 3328 pts in the use of MIPD: 🇺🇸🇨🇦7%, 🇩🇪4%, 🇳🇱17%, 🇸🇪0.1% and rapidly changing still
▶️in-hospital/30-day mortality 🇺🇸🇨🇦2%, 🇩🇪7%, 🇳🇱4%.
▶️ link.springer.com/article/10…
💡LIDOPAN study: multicenter pilot trial
💉 IV lidocaine for patients in pain with PDAC and CP
👥30 patients, NRS >4
📈 No overall clinically relevant pain reduction day 1
🤩 31% positive effect, lasted op to a month
ncbi.nlm.nih.gov/pubmed/3916…
@ACG_CTG
Simone Augustinus retweeted
In @AnnSurgOncol, #GAPASURG study 🇺🇸🇨🇦🇩🇪🇳🇱🇸🇪 with 2924 #PancreaticCancer patients on DP-PVR vs. standard DP.
DP-PVR 🟰
⚠️associated with ⬆️ in-hospital/30d major morbidity (24% vs. 18%);
⬆️CR-PPH (10% vs. 3%)🩸;
✅NOT associated with in-hospital/30d mortality (1.7% vs. 1.2%).
Very honored to give the @YouppiePancreas award 🏆presentation at #EPC2024: looking beyond trial results in pancreatic research ⭐️
Key points:
1️⃣ Improve international comparison
2️⃣ Use of alternative RCT designs
3️⃣ Importance of implementation
@DPCG_official
Simone Augustinus retweeted
🗣️TOMORROW THURSDAY JUNE 27th‼️
🔥1️⃣0️⃣:0️⃣0️⃣🔥@ #EPC2024
The amazing💥 YOUPPIE awardees @Simone_Aug and @ThomasHankMD will give their talks🏆
👉 BE THERE 💜💜💜!!!!!!!!!!!!!!
Simone Augustinus retweeted
How do the use and outcome of Minimally invasive Whipple compare between 🇺🇸 🇳🇱🇩🇪🇸🇪? Gapasurg.com @nine_degraaf
Big differences! Highest use in 🇳🇱 17%, lowest in 🇸🇪 0.1%.
Conversion rates lowest in 🇳🇱, especially robot 9%. #IHPBA24
Simone Augustinus retweeted
Two lectures, one message: input of female hpb surgeons is increasing @IHPBA @EAHPBA @AHPBA #APHPBA: but not enough!
Bill Jarnagin, in his presidential address & @MinterWiscSurg:
➡️We need female presidents⬅️
#LetsDoIt
@iisifrigerio @HalletJulie @HoggNDMD @AisteGulla @carlijnbuis @mary_dillhoff @MissJanetKung @Surgerygirl8 @asuhool @JonyvanHilst @TessvRamshorst @nine_degraaf @TEHendriks @julia_menso @LC_Leeuwenburgh
Simone Augustinus retweeted
It’s a wrap. #europeansurgicalassociation
Fantastic start with the next generation of surgeon scientists @Simone_Aug @MarkarSheraz Fantastic presentations over the days! @MA__Schneider and an impressive Gala Dinner!
@shahidfarid @profpeterlodge
@uktuebingen
Simone Augustinus retweeted
Last day - Spread the word 💜💜👇👇‼️
@AnaDugic @LumirKunovsky @SN_gastro @CSKnoph @SimonSirtl @Simone_Aug @ThomasHankMD @Lguilabert1 @HughesDLlwyd @vasyb @mstotty88
💜Come join us in amazing Santiago de Compostela 🇪🇸 #EPC2024
‼️TODAY May 6️⃣th is the LAST day to register with Early Bird Fee 🐦🐦🐦
Don't miss your chance to save 💵 !
👉epc2024.eu//inscripcion
Kick off next generation ESA 🇪🇺
👨🏾⚕️ Do’s and don’ts during surgical fellowships @MarkarSheraz
💵 How to obtain funding for research @BrunsChristiane
⭐️ The road to academic succes #PiereAlainClavien
➡️ All highlighting importance of: mentorship, diversity and perseverance!
Simone Augustinus retweeted
In this randomized clinical trial, implementation of 5 best practices in pancreatic cancer care did not improve 1-year survival and quality of life. Findings highlight the need for more personalized treatment options. ja.ma/3UcszfV @MarcBesselink
Very gratefull for winning the YOUPPIE award 🌟
Looking very much forward to presenting at the EPC & meeting all new @YouppiePancreas friends 🙏
➡️Towards many more future projects with o.a. @DPCG_official and #Pancreas2000 🇪🇺
🔥🎉YOUPPIE AWARDEES 2️⃣0️⃣2️⃣4️⃣🎉🔥
We congratulate @Simone_Aug and @ThomasHankMD who, in a very tough competition, receive the YOUPPIE awards of 2024 👏🏆!!!
Thank you to all the contestants 🙏💜
Hear our winners talk about their amazing research at #EPC2024 in🇪🇸 June 2️⃣7️⃣th
Are you an aspiring young academic surgeon? ⭐️
European Surgical Association (ESA) mentorship program deadline April 1st 🇪🇺
&
ESA Next Generation meeting before the conference (incl networking 🙏)!
More information:
europeansurgicalassociation.…
#ESA #Leeds #May2024 #BeThere
Simone Augustinus retweeted
In this randomized clinical trial, implementation of 5 best practices in pancreatic cancer care did not improve 1-year survival and quality of life. Findings highlight the need for more personalized treatment options. ja.ma/48gQQVW @MarcBesselink
Our master-project in print 🤩 🇳🇱 @JAMASurgery
‼️ Main message: 61% of all pancreatic cancer patients does not receive tumor directed treatment!
➡️ This warrants further investigation
Can one randomize all patients with #PancreaticCancer in a single country 🇳🇱 in a stepped-wedge RCT to improve guideline-based care? Yes✅ #PACAP1
Did this improve treatment nationwide? Yes, partially✅
Did this improve survival? No⛔️
🔑 Why? 61% of 5800+ patients received no cancer-directed treatment… @DPCG_official
Today: #PACAP1 trial in @JAMASurgery jamanetwork.com/journals/jam…
