AI-powered multiomics & bioinformatics. An affiliate of MedGenome. Global RWE to support discovery in oncology, rare disease & more. https://xitter.cf/t.co/dIzpUsKevd
Foster City, CA
Joined March 2025
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We’re heading to #ASH2025 in Orlando. Visit Signios Bio at Booth 165, Dec 6–9.
Learn how we support hematology research with single-cell RNA seq, spatial transcriptomics, bulk sequencing and TCR/BCR profiling. Schedule a time to connect
hubs.ly/Q03WjMm00
Checkpoint response reflects clonal expansion, transcriptional state, and spatial context in the TME. Signios provides immune profiling from bulk TCR/BCR sequencing to single-cell V(D)J analysis for immuno-oncology research. hubs.ly/Q03QPTh70
#ImmunoOncology #TCRSeq #BCRSeq
Antibody repertoires reveal how B cells shape the immune response in cancer.
Our RNA-based BCR workflows capture full-length chains and quantify diversity, even from FFPE samples.
Read the white paper: hubs.ly/Q03QGn440
#BCRSequencing #RNAseq #ImmunoOncology
Visium HD or Xenium Prime 5K? Two paths to spatial insights—one for broad, unbiased discovery, the other for targeted, cell-level precision. Read how each fits discovery and validation workflows: signiosbio.com/blog/10x-visi…
#SpatialBiology #SingleCell #SpatialTranscriptomics
SigniosBio retweeted
The Future is Single-Cell Long-Read @GeneticsSociety
Thanks to all the innovators we had exciting discussions with about how to advance the Single-Cell Long-Read space. STAY TUNED! @PacBio, @nanopore, @Roche, @Singleron_Bio, @TwistBioscience, @ParseBio, @BioRad, @RNA_Connect, @SigniosBio, @GenomeWeb
Last chance: Live webinar tomorrow, 10:00 am PT. Single-cell with tumor genomics and transcriptomics in multiple myeloma. Register: us02web.zoom.us/webinar/regi… Can’t make it? Register anyway, get the recording. #MultipleMyeloma #SingleCell
Signios is at #ASHG2025! Find us at Booth 2603, end of Row 2500. Ask about our free RNA-seq offer, long-read sequencing with @PacBio, and single-cell, spatial with @10xGenomics and proteomics solutions @OlinkProteomics. signiosbio.com/sequencing-se…
Live webinar with Dr. David Coffey (U Miami): integrating tumor genomics , transcriptomics and immune single-cell profiling in multiple myeloma. Oct 21, 10:00 am PT. Register: us02web.zoom.us/webinar/regi…
#MultipleMyeloma #SingleCell #CancerResearch #ImmunoOncology #Genomics
As #AlzheimersBrainAwarenessMonth ends, see how single-cell, spatial & long-read sequencing are used to study brain complexity in TBI, FTD, FA & Alzheimer’s.
Read more: hubs.ly/Q03svdbM0
#NeuroscienceResearch #Genomics
#BrainAwarenessMonth: Prof. Theus (Virginia Tech) on #TBI research with Signios Bio: “…we validated signaling at the protein level and tested it therapeutically in our model.” Multiomics made it possible. Read the TBI story: hubs.ly/Q03rZXKD0 #Multiomics #ScienceOfSignals
It’s still #BrainAwarenessMonth. Signios Bio supported scRNA-seq in a progranulin deficiency study, uncovering diverse microglia-like cells: hubs.ly/Q03rZzsC0
Explore our single-cell services: hubs.ly/Q03rZR7T0
#scRNAseq #Genomics
For #BrainAwarenessMonth: Stanford study (w/ scRNA-seq + bioinformatics by Signios Bio) reveals 6 microglia-like cell subtypes in a model of progranulin deficiency (#FTD). New insights into CNS cell replacement. Preprint: hubs.ly/Q03rZDK-0
#scRNAseq #ScienceOfSignals
It’s Alzheimer’s & Brain Awareness Month. Signios Bio supports brain research with Neuroregulation Signal (to identify vulnerable neurons) and Neuroimmune Signal (to map immune activity). Learn more: hubs.ly/Q03rZy6y0
#BrainAwarenessMonth #Neuroscience #ScienceOfSignals
New grant alert! Illumina & Signios Bio are offering no-cost proteomic analysis (up to 170 samples, 9.5K proteins via NovaSeq) + expert support + a chance to present your work. Apply by June 27!
Press release: hubs.ly/Q03nc1SW0
Apply: hubs.ly/Q03nc2wv0
Advancing #ImmunoOncology research? Check out our latest application note on how single-cell profiling revealed immunologic signatures of response and resistance to ICIs in metastatic cancer. hubs.ly/Q03mF0c00 #SigniosBio #ImmunoOncology #SingleCell #ScienceOfSignals
See beyond the genome with HiFi sequencing to directly map DNA methylation (5mC, no bisulfite!) & resolve complex SVs missed by short reads. Explore cancer epigenetics & genomics with #SigniosBio hubs.ly/Q03mDrqM0 #Hi
SigniosBio retweeted
More data, less DNA. With #SPRQ chemistry, Signios Biosciences is unlocking #HiFisequencing for tough samples—boosting output and expanding access to more sample types.
🔗 See how they’re using SPRQ to scale impact and access: bit.ly/4jgpTbn
#PacBio #PacBioSPRQ
Short-read RNA-seq missing key cancer transcript details? #SigniosBio's long-read RNAseq provides full-length clarity on isoforms, fusions & splice variants. Get in touch to learn more. hubs.ly/Q03l4XHq0 #IsoSeq #HiFiSequencing #RNA #CancerResearch #ScienceOfSignals
See the bigger picture in cancer with #SigniosBio's PacBio #HiFi long reads. Detect SNVs, Indels, SVs, full-length RNA isoforms & DNA methylation (#5mC) in one workflow. Explore what's possible: hubs.ly/Q03klNb_0 #LongReads #CancerGenomics #Epigenetics #ScienceOfSignals
Happening Today! Join @MukeshKNyati at #AACR25 to hear how #SigniosBio's spatial transcriptomics mapped the TME in KRAS models. Catch Dr. Nyati at Booth #2364 at 2pm today to discuss the findings!
#SpatialTransciptomics #CancerResearch #ScienceOfSignals
