@SerreLab

Professor at the Institute for Genome Sciences and Dept of Microbiology and Immunology- University of Maryland School of Medicine

 Baltimore, MD
Joined August 2018
  • Tweets237
  • Following244
  • Followers744
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David Serre retweeted
Manuel Llinas@LlinasLab1 Sep 2023
The Llinás lab (@Llinaslab) is hiring in the space of Plasmodium transcriptional regulation and metabolism (@MalariaPsu, @PSUScience, @BMB_PSU, @cegrPSU ,@ciddpsu)! If interested, please email, DM, or apply here: tinyurl.com/Llinas-PD
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I am looking for postbac or postdoctoral researchers! Anyone interested in applying whole genome sequencing, dual RNA-seq, scRNA-seq and/or spatial transcriptomics to study host/pathogen interactions during malaria infections?
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New paper from the lab: @TebbenKieran characterized host and parasite gene expression using whole blood from Malian children successively infected with P. falciparum and P. ovale journals.plos.org/plosntds/a…
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She found that the host gene expression profiles clustered by individuals rather than according to the Plasmodium species causing the infection doi.org/10.1371/journal.pntd…
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She also identified both P. ovale curtisi and P. ovale wallikeri (in only four infections) and observed comparable levels of genetic diversity in P. ovale and P. falciparum (despite their massive difference in prevalence in Mali)
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New(ish) paper from the lab: @AlmostDrHazzard combined @10XGenomics scRNA-seq with @PacBio sequencing to characterize full-length isoforms of Plasmodium vivax at the single cell level journals.plos.org/plosntds/a…

Long read single cell RNA sequencing reveals the isoform diversity of Plasmodium vivax transcripts

Author summary Single-cell RNA-sequencing is a valuable tool for identifying gene expression differences among cells present in one sample. However, scRNA-seq data is usually generated by sequencing...

journals.plos.org
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… and many of the isoforms were regulated in a stage-specific manner, suggesting that alternative promoter usage may be an important mechanism for regulating gene expression throughout the Plasmodium life cycle.
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gft file containing these new annotations (to facilitate further analyses of bulk and scRNA-seq data from P. vivax): doi.org/10.1371/journal.pntd…
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Replying to @SalmanF70432683 @SerreLab @PostdocPhd
Feel free to apply to our Genome Biology Track for a PhD! We have added two new courses on genomic data science and applications. lifesciences.umaryland.edu/m…
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I am looking for postdocs! Anyone interested in applying dual RNA-seq, scRNA-seq and spatial transcriptomics to study host/pathogen interactions during malaria infections? No prior experience in microbiology/parasitology required.
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New study by @TebbenKieran to infer the stage composition of P. vivax or P. falciparum infections from bulk RNA-seq data. journals.asm.org/doi/10.1128…

Determination of the Stage Composition of Plasmodium Infections from Bulk Gene Expression Data |...

Differences in cell type proportions among samples can introduce artifacts in gene expression analyses and mask genuine differences in gene regulation. Gene expression deconvolution allows estimation...

journals.asm.org
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I am pleased to announce that @UMBaltimore is commencing a national search for the next dean of the @UMmedschool to succeed E. Albert Reece, MD, PhD, MBA, who announced his retirement in March. We expect to name the new dean by spring 2022. umaryland.edu/president/lett…
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Interested in research at the cross section of infectious disease and immunology? We're looking for two postdocs! We have tons of projects on vaccine research, flu studies, adjuvant development, and more! Please share and send a cover letter and CV to [email protected]
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Anyone interested in studying host/pathogen interactions in ticks using RNA-seq, scRNA-seq and spatial transcriptomics?
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.@MattVCannon1 @SerreLab and colleagues present a sequencing-based assay that could significantly improve monitoring of human and animal vector-borne pathogens. In their work, the team characterise a wide-range of eukaryotic parasites and arboviruses: ow.ly/ii8050FG5Ah.
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Please help us plan the Molecular Parasitology Meeting #MPM2021 this Fall by taking a short survey. In person/virtual/hybrid? Nina, Manoj & Boris @TrendsParasitol @BSPparasitology @AS_Para @ParaFrap @ASTMH @GeneticsGSA @MBLScience @MBLBoP Please RT. upenn.co1.qualtrics.com/jfe/…
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We are recruiting new junior PIs for infectious disease research @CiidHeidelberg through generous support from the Chica and Heinz Schaller foundation. We offer fantastic colleagues, students, equipment, networks - all in one of the most livable cities. Please RT, please apply.
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David Serre retweeted
Michael Blum@mblum_g20 May 2021
La vie de chercheur en chanson youtu.be/THh5F7TlHY8 Trop. bon.
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David Serre retweeted
Genomics@Genomicsltd12 May 2021
If you’d like to help build a massive, genomics driven, analytical machine for understanding human disease, with immediate translational impact, then this job might be for you. careers.genomicsplc.com//job…
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