@SSadnro

Scientist

 Milano
sandrobottaro.wixsite.com/sandrob
Joined October 2012
  • Tweets970
  • Following523
  • Followers508
130Media
Proud to share our latest work led by X-less Oliver Dutton! We've demonstrated that inverse folding models can be substantially improved at protein stability prediction without additional training or data. 1/4
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Julian Streit@JulianStreit3Jan 21
New preprint with @inve_michele, @SSadnro, @KamilTamiola, and @LindorffLarsen on atomistic simulations of disordered proteins, using enhanced sampling to uncover some order within disorder. biorxiv.org/content/10.64898…
bioRxiv Biophysics@biorxiv_biophysJan 21
Transient tertiary structure in intrinsically disordered proteins revealed by multithermal enhanced sampling biorxiv.org/content/10.64898… #biorxiv_biophys
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Michele Invernizzi@inve_micheleJan 21
Sampling IDPs is tough, but can be worth the effort! OPES multithermal made it a little easier for us, hopefully you'll find it useful as well @PeptoneLtd
Julian Streit@JulianStreit3Jan 21
New preprint with @inve_michele, @SSadnro, @KamilTamiola, and @LindorffLarsen on atomistic simulations of disordered proteins, using enhanced sampling to uncover some order within disorder. biorxiv.org/content/10.64898…
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Transient tertiary structure in intrinsically disordered proteins revealed by multithermal enhanced sampling biorxiv.org/content/10.64898… #biorxiv_biophys
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Walking around Naples in a Juventus shirt…. With Maradona on the back 😂
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Hey @Ryanair @Ryanair_IT two months trying to get assistance for my dad disabled & on dialysis. Radio silence. We’re not asking for VIP perks, just basic human support.
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Still no word from @Ryanair_IT @Ryanair but at least the scammers are showing real interest in my case. Nice to know someone cares
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@Ryanair is this account legit?
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Maybe @Google or @GoogleDeepMind should fund CASP, given their ample resources and how much they've benefited from the efforts of John Moult, Krzysztof Fidelis, Andriy Kryshtafovych, Nick Grishin, and many others. science.org/content/article/…

Exclusive: Famed protein structure competition nears end as NIH grant money runs out

Agency silent on funding renewal for contest that inspired creation of AIs that predicted how proteins would fold

science.org
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Zoe Cournia@zoecournia12 Jun 2025
Please RT! I have 2 postdoctoral positions in my lab @BRFAA_IIBEAA to work on MD sims for protein allostery, cryptic pocket identification, CADD/FEP. Knowledge in coarse-grained MD is a plus. More info: linkedin.com/hiring/jobs/424…. Send me an email with your CV if interested!

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Un caro ringraziamento a @SEA_Press per averci abbandonato sulla pista di Malpensa alle due di mattino
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Adam Pecina@madAniceP9 Jun 2025
🚨 Program Update: CADD GRS 2025! We're excited to welcome @wpwalters as our keynote: "AI in Drug Discovery – Revolution, Evolution, or Complete Nonsense?" A perfect kickoff for an inspiring weekend in Portland! 🔗 grc.org/computer-aided-drug-… #CADDGRS2025 #compchem #DrugDesign
Adam Pecina@madAniceP23 May 2025
🏁 Program is live for the 2025 GRS on Computer-Aided Drug Design! Overwhelming interest, top-tier abstracts, and a fantastic lineup incl. keynote Charlotte Deane + stellar mentorship panel. Can't wait! 🔗 grc.org/computer-aided-drug-… #CADDGRS2025 @GordonConf #CompChem #DrugDesign
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Just published in @NatureComms our new paper integrating #MD and #cryoEM data to construct structural ensembles of complex #RNA macromolecules 🎉✨🥳nature.com/articles/s41467-0…. Excellent work by @ElisaPos with @BussiGio @BonomiMax @PJanosJr N. Toor, D. Haack
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Il barolo ce lo terremo per noi youtu.be/aaZZxHiidNk?feature…
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🚀 New preprint alert! 🚀 Introducing Loxodynamics, a simple yet powerful deep learning method for exploring chemistry and catalysis by biasing skewed distributions. Check it out! 🔬⚡ #MachineLearning #Catalysis #Chemistry chemrxiv.org/engage/chemrxiv…

Exploring Chemistry and Catalysis by Biasing Skewed Distributions via Deep Learning | ChemRxiv

The automated discovery of chemical and catalytic reactions remains a major challenge in computational chemistry, particularly in complex systems where conventional methods struggle to identify...

chemrxiv.org
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#RNA rules
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Giovanni Bussi@BussiGio20 Feb 2025
Interested in #RNA modelling across multiple scales? Join us for the @cecamEvents meeting at @Sissaschool, Trieste, May 19-22! cecam.org/workshop-details/r… We still have slots for contributed talks. Deadline March 23. Co-organized with @Magistrato_Lab and @devivo_marco
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Gabi Heller@G_T_Heller12 Feb 2025
I’m delighted to share that @ThomasLhr1, @gogulan_k, and I are launching @bindresearch, a UK-based not-for-profit research startup to deliver publicly–available tools and datasets to make intrinsically disordered proteins druggable. 🍝 💊🧲 💻 🦠
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Oggi è il compleanno di Angelo Badalamenti, il che significa che è il giorno perfetto per condividere per l'ennesima volta il video più bello di tutto l'Internèt: quello in cui racconta di come lui e Lynch hanno scritto il tema musicale di Laura Palmer.
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We discovered 3 RNA families that form homo-oligomeric RNA-only complexes! Studying nature continues to expand my wildest imagination. Read about it: doi.org/10.1101/2024.12.08.6… Vivian Wu, Svetlana Shabalina, Hyunbin Lee, Grace Nye, Eugene Koonin, Alex Gao, @RDasLab @chiulab
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Anubi era un alieno che veniva dalla costellazione del canis poi sono tornati nelle loro galassie e gli antichi egizi hanno detto che era il protettore dei defunti ma non era vero
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