@simonsfdn postdoc fellow @BigelowLab @rstepanauskas Lab | @faylward lab alum | I like big phage & I cannot lie, aspiring Wumbologist 🦠🧬🌊🆒
East Boothbay, Maine
Joined November 2012
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What if we could put all tailed phages in a single, evolutionarily meaningful phylogeny? Check out the latest from the Aylward Lab (twitterless) and myself - we present a phylogenomic framework toward unifying phage diversity! 🧬🤝 biorxiv.org/content/10.1101/…
Congrats to @chang_tianyi @julesinboots @stepanausk8197 on helping the environmental microbiology community better understand the strengths and weaknesses of SAGs versus MAGs! Using either/both data types? Read this to more accurately interpret your data link.springer.com/article/10…
Alaina Weinheimer @[email protected] retweeted
How many SAR11 cells are phage-infected in the environment? And what are zombies🧟♂️?
We studied phage infection in SAR11 using the🔬. Up to 19% of SAR11 cells were phage infected and many host cells were devoid of ribosomes🧟♂️!
What else did we find? A 🧵
researchsquare.com/article/r…
Alaina Weinheimer @[email protected] retweeted
Super cool paper from Ernie Osburn, @Gaowen_Yang @mrillig and @strickm27 showing that alpha-diversity relationships with soil ecosystem function are non-causal.
"We show... microbial community membership and abundance characteristics, rather than α diversity, most strongly predict ecosystem functions and... are more likely to represent the direct microbial drivers of functional changes at the ecosystem scale."
nature.com/articles/s43705-0…
Alaina Weinheimer @[email protected] retweeted
Can large language models understand genomic sequences and uncover new biology? 🧬🧬🧬 Excited to share a new #preprint with @sokrypton, @ancornman1, and @pgirguis. TLDR: A Large Language Model for genomic sequences! #genomics #AI #machinelearning #NLP
biorxiv.org/content/10.1101/… 1/
Instead of asking “did you feed the cat her wet food?”, we ask “were you the hero today?” And I’m only now realizing how sad it is that we have to exaggerate our importance to her to convince ourselves she needs us bc cats
Alaina Weinheimer @[email protected] retweeted
New paper alert!🌋🌊🧬🦠 I'm so excited to share our paper "Viruses interact with hosts that span distantly related microbial domains in dense hydrothermal mats" 1/ nature.com/articles/s41564-0…
Casually asked my friend “do you know Bob’s Red Mill flour?” , and just realized the full depths of my baking addiction mindset
Alaina Weinheimer @[email protected] retweeted
Excited to share our new preprint! Phage tRNA act as a counter to the Retron defense system, and Rad is a broad-spectrum retron inhibitor.
biorxiv.org/content/10.1101/…
Alaina Weinheimer @[email protected] retweeted
In @Nature today (open access), we report the structural and mechanistic basis of how bacteria harvest energy from air. We reveal a novel enzyme, Huc, consumes atmospheric levels of hydrogen gas and transfers the derived electrons for aerobic respiration. nature.com/articles/s41586-0…
Alaina Weinheimer @[email protected] retweeted
Do you have a crappy phage? Do you have 4 days? We found that we could rapidly evolve our bacteriophages to increase low titers by 100-10,000 times in only four days! In many cases, the host ranges expanded at the same time! Amazing! Try it! #Phage #Evolution @kok_danielle
In Vitro Evolution to Increase the Titers of Difficult Bacteriophages: Rapid Appelmans Protocol biorxiv.org/cgi/content/shor… #biorxiv_micrbio
Alaina Weinheimer @[email protected] retweeted
Still looking for a postdoc in soil viral ecology, start date flexible, bioinformatics/omics background useful but you don't need virology experience, apply by March 6 if possible
Postdoc at UC Davis in soil viral ecology now open for applications. Apply by March 6 if possible, start date flexible. recruit.ucdavis.edu/JPF05497
Is it acceptable yet to have a cat/pet in your professional headshot? (The only recent pics I have of just me currently without alcohol)
81%Yes
19%No
31 votes • Final results
Alaina Weinheimer @[email protected] retweeted
Four principles to establish a universal virus taxonomy
journals.plos.org/plosbiolog…
It was a wonderful experience to share a workshop with world experts on virus diversity, genomics and classification.
Alaina Weinheimer @[email protected] retweeted
Impact of microbial genome completeness on metagenomic functional inference | ISME Communications nature.com/articles/s43705-0…