Neuroscientist in Copenhagen, Dept. of Neuroscience @neuroscience_dk | PI at @BergLabCPH | Motor control | Networks | Spinal Cord | PhD from UC San Diego
Copenhagen
Joined June 2009
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New paper:
How does the spinal cord generate walking? Our answer: the spatial structure of the network of spinal interneurons forms the basis of the generation of movement. 🧵
nature.com/articles/s41467-0…
New view on spinal motor function!
Nearly every movement we make is partially generated by the spinal cord. Yet how remains a mystery, even though it is one of the oldest subjects in modern neuroscience, studied since Sherrington.
Details here:
doi.org/10.1016/j.conb.2026.…
What does a spinal cord flexor/extensor half-center spiking network's activity look like in neural state space?
It has a characteristic V-shaped trajectory and a very low-dimensional population dynamics (simulation below).
Rune W. Berg retweeted
A 14-year-old teenager from Chelyabinsk recorded a message to Putin
“I can no longer stay silent. I want you not just to end the ‘special military operation,’ but to disappear from our country, from our news, from our homes, from our fears — and never come back again,” he says in the video.
Rune W. Berg retweeted
In the last few weeks, AI agents have autonomously:
* taken over OpenAI's internal servers
* uploaded malware to GitHub, and posed as users asking for it be accepted
* launched swarm attacks on websites hosting AI benchmarks
Let's check the news!
Rune W. Berg retweeted
The Sauerbrei Lab at Case Western Reserve University is recruiting a postdoctoral scholar to work on neural dynamics and motor control:
apply.interfolio.com/189987
7/ thanks to our funding agencies:
Lundbeck (no. R366-2021-233, R.W.B.), Novonordisk (no. NNF23OC0082192, R.W.B.), Swiss National Science Foundation (no. SNF Postdoc.Mobility P500PB_206824, S.K.), and EIC Pathfinder 101130161-Move2Treat.
6/ Prediction: local rhythmicity in a segment is not its own thing — it's a slice of a traveling wave crossing the cord. Open access, code and data available. Congratulations to @SalifKomi and the whole team.
5/ It also reproduces classic perturbations. Silencing V1 slows the rhythm (a long-standing puzzle — here it's a wave-propagation effect). Silencing V0 speeds it up and flips left–right alternation into hopping.
4/ Gain modulation of single populations then gives clean, near-independent control: local excitation sets amplitude, ascending inhibition sets frequency. Descending drive from LPGi + raphe 5-HT walks the model from walking → bounding.
3/ That asymmetry is the engine. It turns standing activity bumps into traveling waves—rhythm, rotational dynamics, and left–right alternation —with no pacemaker cells and essentially no parameter tuning.
2/ Building a mouse lumbar cord from snRNAseq + spatial transcriptomics, with synapses sampled probabilistically from cell-type projection patterns, one motif falls out: local excitation, longer-range inhibition, with a longitudinal skew. An asymmetric "Mexican hat."
What is the neural "software" behind movement?
My talk on the topic at the VVTNS is now online----
"Neural Manifolds in Spinal Networks That Orchestrate Movement"
youtu.be/sbQx5gWxtcE?si=x00u…
van Vreeswijk Theoretical Neuroscience Seminar
New preprint:
"Neural manifolds that orchestrate walking and stopping".
Introducing a neural theory for walking and stopping. We test the theory using Neuropixels probes in the lumbar spinal cord of freely moving rats.
See more:
biorxiv.org/content/10.1101/…
New paper out: Using synthetic diamonds as growth medium for bridging an injury in the nervous system. Congrats Jaspreet, Jakob and the rest of the team!
@Kaur13Jaspreet
sciencedirect.com/science/ar…
Rune W. Berg retweeted
Apply now for our #Neurotheory workshop @HHMIJanelia where we’ll dive into techniques in #TheoreticalNeuroscience and build community through peer-led talks & tutorials.
✈️ Travel, lodging & registration covered
Apply by Aug. 5 @ janelia.news/THE25
🚨 Applications are open!🚨
Students & postdocs in #TheoreticalNeuroscience 👉 Join us @HHMIJanelia this November for a student-led workshop packed with:
🧠 Deep dives
🗣️ Chalk talks
🤝 Small group discussions
✈️ Travel, lodging & registration covered
Apply by Aug. 5 @ janelia.news/THE25
Congrats!
Happy to share this new paper from the lab in collaboration with George Augustine, characterizing synaptic connectivity between the claustrum and the anterior cingulate cortex. Congratulations to Roberto, Zach, and all co-authors! @RobertodelaTor
Congratulations Jaspreet! This is an interesting and thorough investigation on the hippocampal theta rhythm and the effect of PPN stimulation. 👍
Our paper on “Pedunculopontine-stimulation 🧠 obstructs hippocampal theta rhythm and halts movement 🚶♀️” is finally published!! Congrats to all the coauthors and our amazing supervisor @RuneWBerg
nature.com/articles/s41598-0…
Rune W. Berg retweeted
Our paper (w/ @maartenfzwart and twitter-less Stefan Pulver) is now out in @J_Exp_Biol! Come learn about how little beetle larvae walk around and infest flour
journals.biologists.com/jeb/…
