@BergLabCPH

Berg Lab at U. of Copenhagen, Dept. of Neuroscience @neuroscience_dk | Motor control | Brain and Spinal cord | Experiment and theory | PI: @RuneWBerg

 Copenhagen, Denmark
berg-lab.net
Joined June 2018
  • Tweets116
  • Following271
  • Followers323
4Media
Walking is an essential part of life- yet we do not know how the nervous system generates the underlying neural programs. Please find our sneak-peek preprint on neural generation of locomotion in the mouse: biorxiv.org/content/10.1101/… Pan-neuronal 1-spot tracks in lumbar cord
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Berg Lab retweeted
Rune W. Berg@RuneWBergOct 7
What does a spinal cord flexor/extensor half-center spiking network's activity look like in neural state space? It has a characteristic V-shaped trajectory and a very low-dimensional population dynamics (simulation below).
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Berg Lab retweeted
Rune W. Berg@RuneWBergJul 28
New paper: How does the spinal cord generate walking? Our answer: the spatial structure of the network of spinal interneurons forms the basis of the generation of movement. 🧵 nature.com/articles/s41467-0…
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Berg Lab retweeted
Rune W. Berg@RuneWBergMay 4
What is the neural "software" behind movement? My talk on the topic at the VVTNS is now online---- "Neural Manifolds in Spinal Networks That Orchestrate Movement" youtu.be/sbQx5gWxtcE?si=x00u… van Vreeswijk Theoretical Neuroscience Seminar

Neural Manifolds in Spinal Networks That Orchestrate Movement | Rune Berg, University of Copenhagen

Van Vreeswijk Theoretical Neuroscience Seminarwww.wwtns.online; o...

youtube.com
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New preprint: "Neural manifolds that orchestrate walking and stopping". Introducing a neural theory for walking and stopping. We test the theory using Neuropixels probes in the lumbar spinal cord of freely moving rats. See more: biorxiv.org/content/10.1101/…
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Wonderful Jaspreet!
Jaspreet Kaur@Kaur13Jaspreet23 May 2025
Our paper on “Pedunculopontine-stimulation 🧠 obstructs hippocampal theta rhythm and halts movement 🚶‍♀️” is finally published!! Congrats to all the coauthors and our amazing supervisor @RuneWBerg nature.com/articles/s41598-0…
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Too busy to read our preprint? Here's an AI-generated podcast of our recent new theory of the neural mechanism of locomotion in mammals: on.soundcloud.com/FQ56dadQAa…

Podcast of Komi et al 2025: "Spatial and network principles behind...

This is an AI generated Podcast of the preprint on "Spatial and network principles behind neural generation of locomotion" https://www.biorxiv.org/content/10.1101/2024.10.03.616472v3.full

soundcloud.com
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Out in this month's issue of Aging Cell. Motor neurons do better in the presence of primary human muscle cells from older exercisers vs non-exercisers 🙏@lundbeckfonden for the Ascending Investigator grant 4 years ago to see this work through doi.org/10.1111/acel.14413

Muscle fibroblasts and stem cells stimulate motor neurons in an age and exercise‐dependent manner

Muscle biopsies were taken from males and females differing in age and exercise habits. Mononucleated cells were isolated and purified into muscle stem cells (MuSC) and muscle fibroblasts (FIB)....

onlinelibrary.wiley.com
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Excited to share that my postdoc work is now on bioRxiv! We identify a role for spinal-projecting serotonergic neurons in control of locomotor behavior.  biorxiv.org/content/10.1101/…

Potentiation of active locomotor state by spinal-projecting serotonergic neurons

Animals produce diverse motor actions that enable expression of context-appropriate behaviors. Neuromodulators facilitate behavioral flexibility by altering the temporal dynamics and output of neural...

biorxiv.org
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First SFN minisymposium on spinal neural population activity.... ever! Minisymposium: "Unveiling the Neural Dynamics Underlying Movement and Respiration in the Spinal Cord and Medulla" Tuesday 9:30 am - 12:00 pm Room S406A See you! #sfn2024 #SfN24 #SFN
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How does the spinal cord produce locomotion? And how do interneurons cell types relate to motor function? Come see our Posters: Monday 8-12: J17 and J18 and read our new preprint biorxiv.org/content/10.1101/… #sfn2024 #SfN24
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Come see our posters tomorrow afternoon on C9orf72 ALS and FTD at #sfn2024 #SfN24 C9orf72 ALS and aging- Poster – 108.18/B118 C9orf72 FTD- Poster 108.17/B117 Gene-environment interaction in C9-ALS- Poster 108.22/B122 And TDP-43 and axon pathology- Poster 108.11/B111
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See you at the #sfn2024 Minisymposium? Unveiling the Neural Dynamics Underlying Movement and Respiration in the Spinal Cord and Medulla Chethan Pandarinath Rune Berg Nick Au Yong Nick Bush Ariel Levine Lan Luan Kazu Seki Tuesday, Oct 8 9:30 AM–12:00 PM Location: MCP Room S406A
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Berg lab on Danish TV together with Nita Farahany about reading thought using neuro-technology - in Danish and English. youtu.be/C9VVFRq4jyI
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Happy Fluorescent weekend! Here shown spontaneous activity in cultured hippocampal neurons from mouse provided by Guanghui Li (@GUANGHU10821614)
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Deadline approaching for the Cajal training course in Bordeaux, France, on the motor system. Check it out! cajal-training.org/on-site/m…
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Schedule now online for the FENS premeeting “Motor control across scales”. Exciting lineup! #fens24 motor-control-satellite-2024… – at Copenhagen, Denmark
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During rhythmic movement, neural activity in the spinal cord is sparse and doesn't show (strong) alternation. Our work showing how a hybrid-CPG model capture this is out in Neural Computation 🧵🪡 @RuneWBerg @SilviaTolu1 @Jessica_Ausborn @neuroscience_dk direct.mit.edu/neco/article/…

Sparse Firing in a Hybrid Central Pattern Generator for Spinal Motor Circuits

Abstract. Central pattern generators are circuits generating rhythmic movements, such as walking. The majority of existing computational models of these circuits produce antagonistic output where all...

direct.mit.edu
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SFN2024 minisymposium -- mark your calendars!: Unveiling the Neural Dynamics Underlying Movement and Respiration in the Spinal Cord and Medulla Chair: Chethan Pandarinath (@chethan), Co-Chair: Rune W. Berg, Tuesday, October 8, 9:30 a.m.–noon sfn.org/meetings/neuroscienc… #SfN24
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Salif gave a great talk today at the annual meeting for Neural control of movement #ncmdub24 here introducing the locomotor manifold with quasi continuous attractor properties. @KomiSalif
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