The Ruepp Lab (@UKDRI @KingsIoPPN) is interested in dysfunctional RNA metabolism in neurodegeneration with a specific focus on the pathomechanisms in ALS/FTD.

Joined July 2019
Very proud supervisor moment! Congratulations to Dr @SaraTacconelli who successfully defended her PhD today! Thanks to @NicolBirsa and Andre Gerber for being her examiners. Thanks as well to @RueppLab for his support. And thank you to the @mndassoc for funding her project!
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Interested in neurodegeneration and synapses then come work with myself and @RueppLab on an exciting @mndassoc funded post doc project 🧠🔬🧫. #alsresearch #synpases #microscopy Research Associate in iPSC and Neurodegeneration at King's College London jobs.ac.uk/job/DKP110/resear…
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Ruepp Lab retweeted
We had a great science exchange and lots of fun at our lab retreat with the @RueppLab - many new ideas for ongoing projects and future joint work on the molecular mechanisms of ALS/FTD!
Last day of our joint group retreat with @DormannL 3 days of exciting science discussions around LLPS, gene expression, and neurodegeneration. Thank you Doro and team. It was absolutely brilliant!
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It was lovely to see so many old and new friends in Edinburgh #RNA24! Inspired by so much great RNA science and wonderful ideas 💡 #noMoreHaggis @RNASociety – at Edinburgh, Scotland
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Had a great time visiting @UKDRI @KingsCollegeLon and talking science with @RueppLab @SMizielinska @ule_lab @isaacs_adrian @JemeenSreed and others! Onwards to #RNA24! – at Darlington, England
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Excited to get started on our key question in #MND to dissect TDP-43 pathology with @RueppLab @bhuvaneish, also in collaboration with @adrianisaacslab
Delighted to announce the recipients of Stage I of our exciting new 'Key Questions' funding scheme - supporting bold, ambitious & boundary pushing research🙌 Find out more about the 8 successful projects👉buff.ly/4b4iXdo
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Honoured & humbled to have won this @RCPhysicians prize! Thank you to Pietro Fratta @FrattaLab & Marc-David Ruepp @RueppLab for their ongoing supervision & mentorship during my PhD. – at Camden Town, London
Proud of Puja for winning the prestigious Royal College of Physicians Presentation Prize today in London for her ongoing mechanistic research on motor neuron disease. Keep up the great work! @RCPhysicians #RCPMed24 #ALS #MND #PhD
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Also at her first #alsmndsymp is another amazing PhD student @LOdemwingie co-supervised by @RueppLab and myself! She has a fab poster covering her exciting project looking at the FET proteins in the CNS.
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Proud moment - Brain bank PhD student @JaimeeK_Neuro presenting her poster at #alsmndsymp @LNDBrainBank
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.@mndassoc funded researcher @SaraTacconelli just presented her work at #alsmndsymp. She’s looking at how a protein called FUS interacts with other proteins in neurons. Sara identified over 300 proteins that interact with FUS, which may help us discover what goes wrong in #MND.
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Great presentation by @SaraTacconelli at #alsmndsymp on her @mndassoc funded PhD work! @RueppLab and I are super proud supervisors 🥹🧠🔬
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Realise this is 20 years since I attended my first -#alsmndsymp in Milan! @RueppLab and I have a tradition of getting our knitting done whilst watching all the amazing talks! @mndresearch
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Paper by the Allain(@ETH_en) Campagne(@rna_smart) and @RueppLab (@KingsCollegeLon)w/ co-first authors @Seb_Campagne & @DanielJutzi "Molecular basis of #RNA-binding and autoregulation by the #cancer-associated #splicing factor RBM39" @NatureComms bit.ly/3ZmJT2O #NMRChat
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I am delighted to announce the publication of our work in @NatureComms. We determined the molecular basis for RBM39 homeostasis and RNA binding. A collaborative work between the Allain lab (Zurich), the @RueppLab (London) and the @rna_smart lab (Bordeaux) rdcu.be/dk8g7
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Excited to present some of the initial work gone into developing a new iPSC model to investigate ALS/FTD developed in the @RueppLab @SMizielinska labs! #GRC #ALS – at Ormont-Dessus, Switzerland
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Kicking off the London @AlzResearchUK Network Centre day at the Royal Society with a brief introduction to the background and goals of the centre by coordinator Joseph Bateman (@BatemanLab). Looking forward to an exciting day with lots of great science! #ARUKLondon #scienceday
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#HNRNPH1 regulates expression of the #neuroprotective cold-shock protein #RBM3 through poison exon exclusion @JulieQLin @DeepakKhuperkar et al @MallucciLab @RueppLab embopress.org/doi/full/10.15…
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Very excited to share that I have been awarded an MND Association Biomedical Project Grant to extend my research time developing novel therapies to correct mis-splicing in #ALS #MND! Feeling delighted & grateful to be able to continue working on a project I care so much about 🧠
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ICYMI, last week the BNA Scholars Programme proudly welcomed seven new bright young neuroscientists to join its latest cohort! This exciting scheme supports the careers of young scientists from ethnic groups currently under-represented in neuroscience: bna.org.uk/mediacentre/news/…
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