Physician Scientist; Prof with tenure and hepatologist with focus on stem cell biology, tissue models, liver disease, infectious diseases, cancer, metabolism
Joined October 2020
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I am excited to share that I have been promoted to Full Professor with Tenure at Weill Cornell Medicine. I want to thank my family, mentors, collaborators, and the many colleagues and friends in and out of the field who have pushed, supported, and helped me over the years.
It would be too many people to acknowledge everyone here but I want to offer my thanks to every one of you.
On Amtrak train 90 to NYP. Not moving yet again. @Amtrak tired of the excuses. 4 hours late on a 3 hour trip. Amtrak execs need to go abroad to learn how to run trains. I'd suggest going to Japan for a start.
Heading down to DC for the AASLD Liver Meeting 2025. Looking forward to presenting our work, seeing the latest clinical innovations, and meeting up with colleagues and making new ones.
Had a great week at the Aegean Conference focused on Liver Diseases. Incredible presentations in the field and wonderful discussions. Lots of learning and a great time meeting with colleagues and new friends. #LiverDisease #AgeanConference #KalimeriKriti
Our latest paper is out in Hepatology. We found that aging causes loss of the unique organization and communication of the cells of the liver. It may inform the development of new therapies targeting age-associated liver dysfunction.
news.weill.cornell.edu/news/…
Major congrats to First author Saloni Sinha who help to lead this project in the lab. We surprisingly found that hepatic zonation is very perturbed and altered and there is development of cells with aberrant gene expression during aging. #Liver #LiverDisease
So it has been a few years now since East Side Access opened. It used to take 42-47 minutes to get to the city...now best case 52-65 minutes. So service is worse by 10-30% percent. Can this be fixed? @LIRR @LIRR_Executive @AssemblymanAriB @CanzoneriFitz9 @RepLauraGillen
Does anyone know what finally wound up and was approved in the House Bill as it relates to the NIH, NSF, and CDC budgets? @NIH
Always great to hear Charlie Rice @RiceLaboratory talk about HBV and HCV. @NYASciences
Had a great @DDWMeeting in San Diego. Always great to present our work, see old colleagues and friends and make new ones!
Behind finishing the post on our collaborative work on HBV with @Yael_David__ and @vivrisca revealing how HBV infection is established in human cells and identifying a potential new strategy to target this virus for cure. #HBV #Epigenetics cell.com/cell/fulltext/S0092…… 🧵to follow
Recognizing the importance that HBV chromatinization plays in regulating this process we tested drug compounds known to impair chromatin formation. One drug CBL137 (currently in clinical trials for other purposes) greatly impaired HBV viral replication and infection.
We believe that further dissection and insights of these processes regulating HBV cccDNA formation and function will identify additional vulnerabilities that could be used to target HBV infection and hopefully drive HBV cure. cell.com/cell/fulltext/S0092…
