Dr. Charles M. Rice & the Laboratory of Virology and Infectious Disease @RockefellerUniv. (Account monitored by lab admin.)

New York, NY
Joined October 2020
Our review is out in JCI! We explore how the magnitude, duration, and cellular compartmentalization of cGAS-STING pathway signaling determine the balance between productive antitumor immunity and tumor-promoting inflammation. doi.org/10.1172/JCI204552
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Alexander Lercher of the @RiceLaboratory studies how fighting off one virus changes the way the immune system responds to a totally unrelated one. His work is uncovering immune pathways that let our bodies adapt to viral threats over time. @SNForg 🔗: bit.ly/43GfYWw
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The virologist, awarded for his part in the discovery of the hepatitis C virus, has helped save the lives of millions of people Charles Rice, Nobel Prize winner in Medicine: ‘It’s a crime that a drug exists that could cure everyone yet not has… dozz.es/ctfi81
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Rice Lab retweeted
Had an incredible conversation with the virologist and @NobelPrize winner Charles Rice at #INGM in Milan. Truly inspiring to share our project on #TPD of #viruses and engage in such stimulating discussions with such a brilliant scientist!
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The @RiceLaboratory has created the first mouse model that closely mirrors what happens when people with hepatitis C develop liver cancer, allowing scientists to study how liver virus infection leads to cancer as well as to test treatments. 🔗: bit.ly/4dCzhGp
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This #PostdocAppreciationWeek, we celebrate postdocs at Rockefeller and beyond! In these short Q&As, we invite you to meet a few of them, hear about their work, and get a glimpse of the interests and experiences that inspire them outside the lab. rockefeller.edu/news/38281-p…
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Leon Seifert, William Schneider, @CatherineFreije, and @Xupeng_Hong representing @RiceLaboratory at the 2025 HBV meeting in Berlin. @HepBFoundation #hbvmeeting
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The latest issue of our research magazine Seek is out! Explore groundbreaking research on infectious disease, how AI is supercharging biomedical sciences, technology that’s changing how scientists view the brain, and more. Read the full issue here: bit.ly/45TEV2t
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We are deeply saddened to share that our friend and colleague Jim Hudspeth passed away on Saturday. We will remember and continue to be inspired by Jim’s integrity, his humility, and his unwavering commitment to discovery. rockefeller.edu/news/38152-a…
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So excited to be in Montreal for #ASV2025. Packed schedule, starting with Keynote speaker and Nobel Laureate, Charlie Rice. 🎊🤩
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A recent study from @WeingartenShira, a former postdoc in the @RiceLaboratory, revealed 4,208 previously unknown proteins that are made by viruses such as influenza and H.I.V. using a new technique called massively parallel ribosome profiling. nytimes.com/2025/06/12/scien…
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New issue online! Cover depicts work from Charles Rice, Alexander Lercher & co. showing that antiviral innate immune memory in alveolar macrophages after SARS-CoV-2 infection ameliorates disease caused by a secondary unrelated pathogen. Image credit: Jessica Johnson @RiceLaboratory @alex_lercher cell.com/immunity/issue?pii=…
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Nice job @alex_lercher!
New issue online! Cover depicts work from Charles Rice, Alexander Lercher & co. showing that antiviral innate immune memory in alveolar macrophages after SARS-CoV-2 infection ameliorates disease caused by a secondary unrelated pathogen. Image credit: Jessica Johnson @RiceLaboratory @alex_lercher cell.com/immunity/issue?pii=…
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A nice summary of Dr. Rice!
In this video from our #OralHistoryProject, @NobelPrize laureate Charlie Rice (@RiceLaboratory) tells the story of his life and work. He describes how he came to study hepatitis C and the unexpected difficulty of developing a replication system. youtu.be/KOPicX90j0g
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A recent Rice Lab paper!
Check out our latest paper published in @PLOSBiology, “A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist.” journals.plos.org/plosbiolog… 🧵1/10
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New findings on how past viral respiratory infections affect future infections with non-related viruses from the @RiceLaboratory could lead to therapies capable of boosting general antiviral immunity. #RockefellerScience rockefeller.edu/news/36603-c…
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