@RobPalumboi
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Growth, startups, Tweets etc. | fCMO @ week over week | Growth Partner at https://nitter.cf/t.co/qGvxkQoHGx | ex-@OutPointHQ, @Borrowell, @ProperlyHomes, @PolicyMeHQ
Toronto, Ontario
Joined June 2012
- Tweets16.5K
- Following3.4K
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The economics of a Neolab.
A neolab is loosely defined as a startup of AI researchers who raises a lot of money pre-production to be able to finance GPU compute to take on a large AI problem.
To buy 1000 GB300s or ~14 NVL72 racks will set you back $125-150M for 3yrs with 15-30% upfront. That’s about ~2-2.5MW.
Thats about enough to do 10^25 flops a quarter and get to a GPT-4 level model which is 1-2 OOMs off frontier for pretraining.
If you post-train on a great open source model, you have a better chance of getting to frontier. The risks are a) you need to spend millions on RL environments too and b) being lapped by another model release while being tied to a base model.
For this to payback, you need to give your customers a better and ideally cheaper inference service than a base model and serve them for long enough to recoup your large investment. Even at 50% margin on inference, to recoup $10M in training means serving ~10T tokens (!) if you price like Fable / Astra given a standard cache read / input / output split ($2/M blended). And you have to justify being better than a release like Opus 5.5 which is even cheaper. Often, you end up charging your customers a huge premium in terms of platform fees and compute fees on top of pure inference.
Meanwhile, every hour you’re not utilizing your GPUs you are burning money so you typically resell this compute back to a broker or run inference for open models / resell spot instances. At below a ~60% utilization on spot, you will still lose money.
Add to that insane cost of talent.
So what can you do with the compute?
- Not play the model game at all.
- Play an entirely different model game (Jev, World Labs) that if big labs played, would either a) cannibalize their business or b) be incrementally not significant revenue c) would cause too much distraction from the main main thing
- Acquire a proprietary data set (Peridodic Labs) in enough volume in a domain of usefulness to eclipse frontier quality. Often happens in robotics, biology, chemistry.
If you do overcome the challenge of building a model that is useful and well priced beyond big labs models, given the huge price of compute, you still need to play in an area where the revenue / compute ratio is signficant and market demand is large enough to payback your compute spend.
It is a difficult game.
Rob Palumbo retweeted
One of the weirdest things I’ve noticed as an adult is that older people are much more willing to rip you off than younger people.
Whether it’s buying a car or a house or hiring someone to do work on your house or hiring a business for any kind of work.
Reliably and consistently I’ve found anyone > 10 years older than me to be pushy, exploitative, and generally willing to screw me over.
I have not had this experience with peers or people younger than me.
And it’s weird because these are people who are often the same age as like my teachers I had in school. You go out into the world thinking older people as a cohort are there to look out for you, and I’ve found it to be literally the exact opposite, weirdly consistently.
Rob Palumbo retweeted
Introducing Synthetic Hospital: an open, fully synthetic longitudinal EHR benchmark with verifiable ground truth!
1,268 patients, 5,602 encounters, zero PHI. Physicians could not reliably distinguish its charts from real ones.
📄 arxiv.org/abs/2609.30027
💻 github.com/sparkcpark/synthe…
✍️ sparkcpark.github.io/posts/f…
Rob Palumbo retweeted
only three things matter in enterprise sales …
1. is there internal pressure/incentive
2. do you have their cell number
3. have they shared insider intel/gossip
New website & positioning ✨: weekoverweek.com is the embedded growth function for ambitious companies.
week over week forward-deploys into high-growth startups and AI companies to find the highest-impact opportunities and execute.
We have full-stack experience across growth and work on whichever activity drives the highest expected value.
After serving as a CEO/founder, COO, and growth leader in venture-backed businesses, I decided to build the growth team I wished I had on speed dial: experienced, AI-pilled/cracked, and accountable for results.
We partner with a limited number of companies so we can go deep and maintain a high bar for performance.
Give me a shout at [email protected] if you're working on a hard growth problem.
Rob Palumbo retweeted
AI is getting cheaper more quickly than any other transformative tech in history. At a given level of performance, cost has fallen ~47%/quarter since 2023.
That’s 4× faster than DNA sequencing, 6× faster than compute, 18× faster than lithium batteries, and (up to 1973) 54× faster than electricity.
Rob Palumbo retweeted
I'm now legally obligated to share that I've joined @SpellbookLegal as CMO.
All jokes aside.
Spellbook already has 5000+ clients in 80 countries, has built the first Autonomous Contract Management platform that handles it all: review, collaboration, and storage.
I am energized by the mission of building the rails for agreements and am honoured to do it alongside some of the sharpest people.
Canada is where Cohere was born. It's the place that raised us, gave our founders an education, and taught them the values with which we build our technology.
Those values?
AI shouldn't take you away from the things you love.
AI should empower you to spend more time with them.
Rob Palumbo retweeted
🇺🇸 Only 54% of Americans now drink alcohol, a record-low since 1939, and down from 67% in 2022, according to Gallup study.
Rob Palumbo retweeted
There are exactly two things you need to do when sharing bad news.
First, minimize, like a fucking psychopath, how much you say before you actually get to the bad news.
Not how was your day. Not we want to share how much everyone enjoyed meeting you.
Literally start the meeting with “So the decision is no.”
That’s it.
Everything else is baking bread for the shit sandwich you’re trying to cook up that absolutely nobody wants to eat.
The second thing you have to do is, is appropriate, say what the next steps are.
That’s it.
“It’s going to be a no. If you’re interested in a year, please reach out.”
“The project has been cancelled. Here’s our plan to reallocate resources.”
“You didn’t get the promotion. Here’s why and what’s next.”
People won’t remember what you did. And people won’t remember what you said. But they’ll remember every time you made them sit in the edge of their chair for 90 seconds while you avoided delivering the news they were pretty sure was coming but you were too nervous to just say right away.
Rob Palumbo retweeted
Alexandr can you and @natfriedman take over Meta Business Manager and Ads Manager next? Thanks in advance!
Rob Palumbo retweeted
patterns in the ai startups that blow up
if you advise enough companies, take enough founder calls, watch enough launches, you start to see repeating structures
here’s the blueprint all of them share:
1. a relentless launch cadence
they never shut up
one of my clients launched every wednesday
higgsfield launches 2-3x/wk
always manufacturing something to talk about
2. one channel = unfair advantage
they’re active everywhere
but one channel carries them
3. a founder who’s the face
the founder is the loudest account in the company
weekly podcasts. vlogs. clip & ugc farms
people know the product bc they know the founder
4. volume over perfection
they never post and chill out
they tell the same story 100 times
for every post that does 10k views, another does 10m
5. no fear of price
the loudest ai companies don’t negotiate
they spray
higgsfield is a perfect example of crazy budgets
6. a second motion once plg breaks
elevenlabs is around $500m arr i believe
the first $300m came from plg
the rest came from enterprise, now 50/50 ish
7. omnipresence over roi
on most channels they stop asking about direct roi
they ask how the whole entire planet hears abt them
scroll anywhere & they’re there
they think blended CAC
growth at the highest level isn’t random
it’s a pattern repeated by everyone with skin in the game
once you see it. you can’t unsee it.
every major company is arriving at roughly the same offering:
persistent memory, email/calendar/messages, browser + computer use, background tasks, proactive notifications, voice, app/tool execution, ambient context, & some notion of a personal agent sitting above everything.
remarkable levels of convergence with very little differentiation whatsoever.
Rob Palumbo retweeted
There are a number of incredible low-margin consumer services that have massively grown their operating profit (and their valuation) through an in-product advertising business:
- Amazon: ~$80B
- Uber: ~$2B
- Doordash: ~$1B
- Instacart: ~$1B
It'll be interesting to see if this creates a modern form of the innovator's dilemma, i.e., enabling agentic use (which is unequivocally pro-customer) cuts deeply to their bottom line, creating opportunity for those that don't rely on ads for their operating profit (e.g., Shopify).
Rob Palumbo retweeted
The vast majority of large companies survive purely by launching things and discovering what works by Process of Elimination.
There is no rhyme or reason -- or conviction -- in anything they do.