Understanding the role of immune dysfunction in sepsis on antibiotic stewardship. Mechanistic study embedded in the ADAPT-sepsis trial. EME funded research.

Joined December 2021
Really great news that @RiscSepsis has now achieved sample size. Remember, @AdaptSepsis continues to recruit as planned with an excellence report delivered by the independent Trial Steering Committee in March 2023. Currently, n=2146 . Keep up the great work everyone 👏
Final participant enrolled and recruitment now complete!!! THANKS to all sites that participated in RISCsepsis. Thanks to amazing staff at sites and amazing staff at @WarwickCTU for managing. @AdaptSepsis @UniofNewcastle
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Final participant enrolled and recruitment now complete!!! THANKS to all sites that participated in RISCsepsis. Thanks to amazing staff at sites and amazing staff at @WarwickCTU for managing. @AdaptSepsis @UniofNewcastle
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Thanks to all @AdaptSepsis sites participating in RISCsepsis. Only two more participants to reach our target!!! Thanks and final push...
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Original sample size of 180 reached. Just got approval for an increase to 198 participants to make up for dropout rate. Final push now. Incredible effort from the RISC sites. 🤞 complete recruitment soon! Thanks All. @AdaptSepsis
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Thanks to those critically ill patients who have also participated in RISC-sepsis. Thanks to all our sites who are making a fantastic contribution. Up to 166 participants enrolled!!! @AdaptSepsis @hellyerthomas @DarkNatter @UniofNewcastle @WarwickCTU
Thanks to our critically ill patients & their loved ones for helping us get closer to an answer on research about their care. 60 patient participants across the UK during Feb - latest study position of 2070/2760. Looking forward to our independent DMEC review on Friday.
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Great that recruitment is going again after a slightly longer than planned Xmas pause. Thanks to @OldhamCO_NHS for recruiting this week! Keep up the good work @AdaptSepsis sites participating in RISC-sepsis 👏 @hellyerthomas @DarkNatter
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Amazing recruitment to RISC with 24 patients in October! Thanks to all sites participating from within the @AdaptSepsis trial. @UniofNewcastle @NIHRresearch @WarwickCTU
Outstanding month from all 4 home nations, 53 patient participants at 21 sites. N=1885. Keep up great work + for @RiscSepsis too. Great team efforts everywhere, with special thanks to @LivCritCare @CriticalCareAUH @NCAresearchNHS @uclh @MFT_Research to name just a few in Oct 👏
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Replying to @iccueducation
@iccueducation are committed to research, contributing to several NIHR portfolio trials and leading recruitment to critical care trials regionally 👏
Greenlight for Shrewsbury and first patient in 👊💥! Thanks to all sites for continued efforts, especially Sunderland, Newcastle, Salford and Oldham for recent recruitment. @AdaptSepsis @WarwickCTU @UniofNewcastle @hellyerthomas @DarkNatter
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Greenlight for Shrewsbury and first patient in 👊💥! Thanks to all sites for continued efforts, especially Sunderland, Newcastle, Salford and Oldham for recent recruitment. @AdaptSepsis @WarwickCTU @UniofNewcastle @hellyerthomas @DarkNatter
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Many thanks to all sites participating in RISC. Thanks to all sites for recent recruitment. And welcome to Bolton! @AdaptSepsis @hellyerthomas @DarkNatter @WarwickCTU
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And thanks to sites participating in mechanistic sub study. Thanks to Aintree, Nottingham, Oldham and Sunderland for recruiting this week!
Thank you to each of our recruiting sites across UK NHS for the huge amount of work offering patient participation during this summer period. The current total is 1754 👏👏👏
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Aintree and St James opened to RISC this week. And enrolments at Newcastle and Aintree! Thanks All. @CriticalCareAUH @newcastle_icu @NuTHResearch @AdaptSepsis @WarwickCTU
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Great to have Nottingham critical care open @NUHCriticalCare. Thanks to Salford @SalfordRoyalCCU for recruiting this week 👏👏👏 @AdaptSepsis
Great to meet @AdaptSepsis investigators this week at @WarwickCTU. Thanks to @OldhamCO_NHS, @iccueducation @RI_STSFT and @newcastle_icu @NuTHResearch for recruiting this week. Looking forward to more sites coming on board soon 🙏
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Many thanks to Sunderland @iccueducation @RI_STSFT, North Tees @NTHFTResearch and Newcastle @newcastle_icu @NuTHResearch for recent enrolments to @RiscSepsis! Looking forward to meeting investigators at the @AdaptSepsis investigators meeting next week.
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Many thanks to research teams at Oldham, Sunderland and Newcastle for enrolling patients this week 👏👏👏 Looking forward to opening more sites from @AdaptSepsis to this mechanistic sub-study 👍 @WarwickCTU @OldhamCO_NHS @iccueducation @RI_STSFT @NuTHResearch @newcastle_icu
Another patient recruited this week! Thanks @SalfordRoyalCCU 👏👏👏 @AdaptSepsis @WarwickCTU
Week 2 of recruitment going strong 💪. Greenlight for Sunderland and Salford. Thanks to Sunderland, North Tees, Newcastle and Salford for recruits this week! @SalfordRoyalCCU @iccueducation @newcastle_icu @NuTHResearch @NTHFTResearch @RI_STSFT @AdaptSepsis
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Great week for RISC-sepsis. First sites open and first patient recruited!!! Thanks to @NuTHResearch @NTHFTResearch @newcastle_icu @WarwickCTU @AdaptSepsis
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