Pediatric hematology/oncology | Stem cell biology | AML | Gene therapy | CRISPR

UT Southwestern
Joined December 2021
High-risk, high-reward research is our whole mode, including pediatric cancer, where the @DickieV Pediatric Cancer Research Fund helps us fill critical funding gaps.
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Richard Voit retweeted
Blood Cancer Discovery@BCD_AACRSep 11
Read this research article by Satish Nandakumar, et al. "Germline noncoding risk variants influence clonal hematopoiesis through altered hematopoietic enhancer activity."aacrjournals.org/bloodcancer… This article was recently presented by co-author Keisuke Ito at #ISEH2026. @neuron81
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Richard Voit retweeted
❓A one-time, durable, and even reversible way to prevent thrombosis? In this preprint, led by @lrbzldz, we show that epigenome editing of 🩸 #StemCells can durably reprogram platelet function: biorxiv.org/content/10.64898…
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Richard Voit retweeted
FDA just approved Kresladi (marnetegragene autotemcel) for severe LAD-I — a disease so rare there are ~25 new cases a year in the U.S. The pivotal data: 9 patients. 100% overall survival. All endpoints met. This approval is a masterclass in how to think about evidence standards when mechanism is unambiguous. fda.gov/news-events/press-an…
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Richard Voit retweeted
In this piece, my mentor Stu Orkin and I (1) marvel at prime editing—discovery to disease correction for 2 patients after just 6 yr—wow Liu, Anzalone, Gori, Malech et al! & (2) consider the challenges to deliver genetic medicine’s promise for 2^n patients nejm.org/doi/full/10.1056/NE…
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We fund researchers like @kennethschen, one of the brilliant minds that is helping to shape the future of cancer research. V Foundation researchers, throughout their careers, have generated $22 billion in additional cancer research funding. We truly fund the best of the best.
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MECOM promotes malignant stem cell–like states in aggressive AMLs by directly repressing prodifferentiation gene regulatory programs. Read the plenary paper in Blood: ow.ly/Nrko50XNqJk #BloodJournal #PlenaryPaper #AML
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Inspiring piece in ⁦⁦@NatureCancer⁩, "An unexpected career in cancer metabolism," highlights Dr. Ralph DeBerardinis & the pivotal moments that prompted him to pursue a career in cancer metabolism. ⁦⁦@CRI_UTSW⁩ ⁦⁦@HHMINEWS⁩ nature.com/articles/s43018-0…
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Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia - by @ShellainaGordon @florian_perner, @Armstrong_dfci, @MAF_Dawson @TheDawsonLab et al. doi.org/10.1158/2159-8290.CD… @PeterMacRes @DanaFarber
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KAT6A and KAT7 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia @NMichmerhuizen, Emily Heikamp, @Armstrong_dfci, @CMullighan and colleagues doi.org/10.1158/2159-8290.CD… @StJudeResearch @DanaFarber
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Be part of the Wagenblast Lab! We are hiring a Lab Manager for leukemia & blood stem cell research at @IcahnMountSinai in NYC, starting July 2025. See ad to apply!
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Excited to share with all our latest work on the use of single cell tools in following IDH mutant AML patients during their treatment! Out today @CellStemCell !! An amazing collaboration with @AkEisfeld & @PapaemmanuilLab & @landau_lab !!! Driven by the impressive @MariaSirenko and @soobeomlee & Zhengxi Sun at @NYUGSOM_Path
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Congratulations to @DanaFarber’s Lara Wahlster, MD, PhD, and Nina Weichert-Leahey, MD, for receiving the American Society for Clinical Investigation Emerging-Generation Awards. Read about Dr. Wahlster at bit.ly/4haxdTW and Dr. Weichert-Leahey at bit.ly/4h6BYxL.
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Incredibly proud of @tGaoTeng from our lab, who is a recipient of the @HHMINEWS-@DamonRunyon fellowship!!! Congratulations, Teng!! damonrunyon.org/news/entries…
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I am so excited to be selected as one of the recipients of the Michelson Prize from the Michelson Medical Research Foundation and the @ImmunomePro! This award enables our lab's research at the intersection of systems immunology, virology, and large-scale genomics research.
Replying to @ImmunomePro
Congratulations to Dr. Caleb Lareau, 2024 #MichelsonPrizes recipient! His work will study the blood virome and answer the critical question: how do humans have vastly different responses to the same infection?
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Congratulations @LWahlster of @DanaFarber who has been named a 2025 Damon Runyon-St. Jude Pediatric Cancer Research Fellow. Read more: bit.ly/42T5TWQ
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