Research Scientist. Infectious Diseases Physician. Professor. MD-PhD Program Director. Innate immunity, intestinal epithelial cells and worms. UMass Chan.
Worcester, MA
Joined May 2017
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Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Check it out!! Stellar matches for our MSTP students!! Congrats to our double docs on this milestone in their professional careers as physician-scientists! These sites are so lucky to have you. We are immensely proud! #Match2026 #MDPhD #UMassChanMatch
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
New publication alert! Five MD/PhD students on the same paper? Now that's what we call collaboration! Congrats to our students, alum, and co-director Dr. Mark Johnson on their new publication!
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Read Pukkila-Worley, MD, is the new director of the MD/PhD program: direc.to/n8PN
Dr. Pukkila-Worley has mentored dozens of MD/PhD graduate students since joining @UMassChan in 2014. The @RPWLab studies host-pathogen interactions and bacterial pathogenesis. @UMassMDPhD
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Looking for an up to date review on dna sensors and their role in autoinflammatory diseases check out this review from @Mingqi7up 👇
nature.com/articles/s41590-0…
I hope this is a helpful review!
Appreciate the opportunity to co-write this review in @NatImmunol with my mentor @FitzgeraldKate. Thanks to all the reviewers' comments which significantly elevated our work and thanks to the unsung artists for their art!
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Online now: Intestinal immunity in C. elegans is activated by pathogen effector-triggered aggregation of the guard protein TIR-1 on lysosome-related organelles dlvr.it/TDP14w
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Join us! My lab @UMassChan is seeking postdocs and research associates who are passionate about how changes in metabolism and epigenetics contribute to cancer development and immune system evasion. DM me for a chat and apply at ummsjobs.com/job/10593/ (postdoc position)
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Exciting to see this launch ! Great training environment for developing physician scientists. Check it out @UMass_Medicine #pstp
We are incredibly excited to launch the new Finberg Physician-Scientist Training Program in the Internal Medicine Residency Program @UMassChan , named in honor of our late Chair, an archetypal physician-scientist. World class training in medicine and science. Please RT.
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Thrilled to announce that I will start my lab in the Division of Gastroenterology, @UMass_Medicine @UMassChan in October 2024!
Stay tuned, will be hiring at all levels for research on how abnormal metabolism and epigenetics contribute to cancer development and immune evasion.
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Welcome to @UMassChan @Silvia_galvan_p 🙂
Super excited to announce that the Galvan-Pena lab will open its doors in the Program of Microbiome Dynamics at UMASS Chan Medical school @UMassChan at the end of summer. If you are interested in all the ways gut immunology can have systemic effects, let’s talk!
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Check out this publication co-authored by 4 of our MD-PhD students! – at Worcester, MA
Check out our latest paper- just out in @PLOSPathogens ! @UMassChan @UMassMDPhD students @Mo_AliNasrallah and @nick_d_peterson in my lab characterize an awesome new mechanism of #immunometabolism: Sphingolipids, nuclear receptors, and pathogen resistance! journals.plos.org/plospathog…
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Proud to be a part of this review addressing identity, structure and function of the mPTP. An impressive team of scientists contributed to this work and perhaps most importantly contrasts consensus with controversies and challenges to the field. @CGM_MGH @harvardmed #mitochondria
Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions | Cell Death & Differentiation. Our review was written by 9 investigators who have pioneered mPTP research nature.com/articles/s41418-0…
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Check out our June researcher spotlight in today's DoM Investigator newsletter, featuring Read Pukkila-Worley, MD. Read his full spotlight here. umassmed.edu/medicine/resear…
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Tagging @tse_elegans @RPWLab
Congratulations to Sammy Tse - joint recipient of the Robert Finberg Memorial Rise Trainee Award @UMassChanPII Innate Immunity Day 2023
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Congratulations to Sammy Tse - joint recipient of the Robert Finberg Memorial Rise Trainee Award @UMassChanPII Innate Immunity Day 2023
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
We're hiring a new postdoc! Come join our vibrant and collaborative lab studying HIV and SARS-CoV-2 virology, persistence and evolution: partners.taleo.net/careersec…
Read more about our group here: jonathanlilab.bwh.harvard.ed…
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
We are thrilled to have trainee awardees @GaliaLiraz @ImmunoKevin @tse_elegans present their research alongside experts in the field at next week's Innate Immunity Day @UMassChan! @UMass_Medicine
The inaugural winners of the Robert W. Finberg, MD, Memorial Research Training Award will present their research on May 10 as part of Innate Immunity Day. Read about them here: direc.to/jmNc @UMassChanPII @tse_elegans @GaliaLiraz
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Out in @ImmunityCP today! My preview of a recent study from Zhu and colleagues (cell.com/immunity/fulltext/S…) identifying Nur77 as a cytosolic sensor of LPS and mitochondrial DNA involved in NLRP3 activation.
authors.elsevier.com/a/1guwb…
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
UMass Chan research published in @ImmunityCP adds to understanding of how hosts differentiate between beneficial and harmful bacteria, teaching us about how our immune systems evolved, Read Pukkila-Worley, MD, says: direc.to/jaxt @RPWLab @nick_d_peterson @tse_elegans
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Our paper on symptom and viral rebound is now out in @AnnalsofIM and was just presented by the lead author @DeoR83 at #CROI2023. I want to explain why and how we did this study, what the results mean and importantly, what it doesn't mean. 1/13 acpjournals.org/doi/10.7326/…
Pukkila-Worley Lab is also @rpwlab.bsky.social retweeted
Happy to share that Brianna’s hard work is now out in @hmg_journal. Her work defines functional defects in EMPF1 patient mutations identified in Drp1. track.smtpsendmail.com/90321…