@LabMears

We study mitochondrial dynamics using structural, functional, and cellular methods.

 Cleveland, OH
pharmacology.case.edu/department/faculty/primary/pages/mears.aspx
Joined June 2018
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  • Followers173
32Media
Very grateful to @LabMears for this fantastic summary of our work identifying a new mitochondrial cristae shaping protein in @CurrentBiology. Be sure to give it a read and check out our paper if you missed it! cell.com/current-biology/ful…
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It is with great sadness that we announce the recent passing of Emeritus Fellow Professor Stuart Ferguson. Stuart will be very much missed by all seh.ox.ac.uk/news/hall-remem…
Professor Stuart Ferguson

ALT Professor Stuart Ferguson

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Happy to share new structure of the Drp1 lattice on a membrane. Great collaboration with @sstaggal using RASTR method. Ray and @KristyRochon did an amazing job pulling this together. biorxiv.org/content/10.1101/…

The Structure of the Drp1 Lattice on Membrane

Mitochondrial health relies on the membrane fission mediated by dynamin-related protein 1 (Drp1). Previous structural studies of Drp1 on remodeled membranes were hampered by heterogeneity, leaving a...

biorxiv.org
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The Vaziri-Gohar Lab is hiring a postdoc. This is a great postdoctoral training opportunity for individuals interested in Cancer Metabolism. Please send your inquiries directly to [email protected]. @LoyolaChicago @LoyolaHealth @CancerResearch @NatureCancer #PancreaticCancer
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Always fun being back at #BPS2024. Be sure to visit Anelise and Yuli on Sunday and Wednesday…
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Anelise did a great job yesterday. Lots of visitors and interest in her work.
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Sad to have missed it (had to head out early today), but I know Yuli always does a great job presenting her science.
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Kristy's Drp1 dimer structure is officially out! Yes, the mitochondrial fission protein is very dynamic, and novel conformations regulate assembly and function. Thanks to @DTaylorLab, Yu and Ramachandran Labs for your contributions. rdcu.be/dywTF
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Special treat to hear from Jenny as she receives the Katz Award in the Membrane Fission, Fusion and Traffic subgroup at #BPS2024.
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Big congrats to Brianna on a successful thesis defense! Couldn’t be prouder.
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Happy to share latest from @KristyRochon highlighting structural changes that regulate mitochondrial fission. Structural Basis for Regulated Assembly of the Mitochondrial Fission GTPase Drp1 biorxiv.org/content/10.1101/…

Structural Basis for Regulated Assembly of the Mitochondrial Fission GTPase Drp1

Mitochondrial fission is crucial for distributing cellular energy throughout cells and for isolating damaged regions of the organelle that are targeted for degradation. This multistep process is...

biorxiv.org
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Great collaborative work with Ramachandran and Yu labs, as well as @DTaylorLab
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Excited to be co-chairing (with @SchmitLab) the @caseccc annual scientific retreat featuring Ted Talks from @CancerConnector, @StanGersonMD, and @DeanBondCSU, and a Keynote address from Dr. Elaine Mardis! Registration now open: case.edu/cancer/events/annua….

Annual Scientific Retreat Archive | Case Comprehensive Cancer Center | School of Medicine | Case...

case.edu
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Cool paper. New protein to consider for mitochondrial fission.
Molecular Cell@MolecularCell15 May 2023
Online Now: The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy dlvr.it/Sp46Fn
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Calling all STEM leaders! 📣 We need your help to reach students who need it most with our #GSMI2023 program. 💜 Please share this with your community and let us know if you have any contacts who would be interested in learning more about @cientificolatin
Cientifico Latino, Inc.
@cientificolatin16 May 2023
📣 We need YOUR help so that #GSMI2023, our program for STEM grad school applicants, reaches the students that need it the most! SEEKING CONTACTS: Deans, dept. chairs, prog. directors, community leaders connected to students that could benefit!! 💜 ➡️forms.gle/wtxzcPc6A8UpjYwY6⬅️

Contact outreach form for GSMI

Please help us spread the word about GSMI, our mentorship program for STEM graduate school applicants from minoritized backgrounds. More info at: www.cientificolatino.com/gsmi If you know of programs...

docs.google.com
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I have been fortunate to work with amazing mentees and colleagues that support each other. This is definitely a team award.
Case Comp Cancer Ctr@caseccc12 May 2023
Case CCC member Jason Mears, PhD, honored with 2023 John S. Diekhoff Award for Graduate Mentoring @cwru @CWRUSOM thedaily.case.edu/medicines-…

Medicine’s Jason Mears honored with 2023 John S. Diekhoff Award for Graduate Mentoring | CWRU...

Jason Mears recognizes his students come from diverse backgrounds and, as such, have unique needs. To best support them, he works to create a learning...

case.edu
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Ice cream lunch with @MarvNieman lab and friends. Beautiful day and great food @MitchellsCleve
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Thrilled to share our latest paper in @NatureCancer co-led by the dynamic duo @DionysiosWatson @d_bayik , now at @SylvesterCancer in collaboration with Hrvoje Miletic’s group in Bergen - a 🧵 (1/n) protect-us.mimecast.com/s/hB…
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That's Awesome! Well deserved Dennis.
Justin Lathia, PhD 🧠🕺🏽@JustinLathia3 Apr 2023
Success chain Monday! From @CCLRI to the 🙌🏾 @SylvesterCancer - congrats to @DionysiosWatson on officially receiving a K99 from the @NCI_Training @theNCI to support his exciting new studies on tumor microenvironment communication with our lab and Antonio Iavarone
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New preprint from the lab describing our latest work on the regulation of mitochondrial homeostasis and MDCs. Congrats to first author @XiaoTianyao! Bonus for anyone @UUtah, @XiaoTianyao will be talking about this work at her thesis defense today at 2 pm! biorxiv.org/content/10.1101/…

Genetic Screen Uncovers a Dual Role for Phospholipids in Mitochondrial-Derived Compartment Biogen...

Cells utilize multiple mechanisms to maintain mitochondrial homeostasis in response to stress. We recently identified a cellular structure, called the mitochondria-derived compartment (MDC), that is...

biorxiv.org
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