@RKaletsky

Worms, genes, orchids. She/her.

 Princeton University
Joined July 2019
  • Tweets63
  • Following93
  • Followers107
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Rachel Kaletsky retweeted
microPublication@Micropub7n29 Aug 2024
In vivo neuron-specific expression of C. elegans reprogramming factor orthologs does not alleviate age-related cognitive decline #micropublication #biology #data #caltechlibrary #Celegans #PhenotypeData #NewFinding #NegativeResult micropublication.org/journal…
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Rachel Kaletsky retweeted
Erik Toraason@EToraason29 Aug 2024
When I started my postdoc, I asked if partial reprogramming could rejuvenate aging worm neurons. It turns out, these worm OSK factors are neutral or even deleterious to C. elegans lifespan and chemosensation! Thanks to @ctmurphy1 and @RKaletsky for their help and support!
microPublication@Micropub7n29 Aug 2024
In vivo neuron-specific expression of C. elegans reprogramming factor orthologs does not alleviate age-related cognitive decline #micropublication #biology #data #caltechlibrary #Celegans #PhenotypeData #NewFinding #NegativeResult micropublication.org/journal…
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RESEARCH | @ChenLesnik, @RKaletsky, @ctmurphy1 et al. (@Princeton): In C. elegans, branched-chain amino acid catabolism is important for maintaining oocyte quality with age 🪱 nature.com/articles/s42255-0…

Enhanced branched-chain amino acid metabolism improves age-related reproduction in C. elegans

Nature Metabolism - Lesnik, Kaletsky et al. show that in C. elegans branched-chain amino acid catabolism is important for maintaining oocyte quality with age.

nature.com
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Rachel Kaletsky retweeted
Yifei Weng@Yifei831555845 Apr 2024
My first first-author paper is now on @elife: The Neuron-specific IIS/FOXO Transcriptome in Aged Animals Reveals Regulatory Mechanisms of Cognitive Aging doi.org/10.7554/eLife.95621.… Yay!
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Online now! Slowing reproductive ageing by preserving BCAT-1 dlvr.it/T3PMkp
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Online now! Enhanced branched-chain amino acid metabolism improves age-related reproduction in C. elegans dlvr.it/T3PMhs
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Enhanced Branched-Chain Amino Acid Metabolism Improves Age-Related Reproduction in C. elegans @ChenLesnik, @ctmurphy1 and coauthors. 👉Oocyte quality deterioration can be delayed, and reproduction can be extended in wild-type animals both by bcat-1 overexpression and by supplementing with Vitamin B1, a cofactor needed for BCAA metabolism. biorxiv.org/content/10.1101/…
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Rachel Kaletsky retweeted
Lifespan News
@LifespanNews9 Oct 2023
Mammals and worms share similar molecular mechanisms for long-term memory formation. lifespan.io/news/a-mutation-… @ctmurphy1 @Princeton
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Neuronal activation of Gαq EGL-30/GNAQ late in life rejuvenates cognition across species @ctmurphy1 @UCSFAging @VilledaLab cell.com/cell-reports/fullte… | @CellReports
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Dendrobium unicum #orchid
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Dendrobium nobile, Violet Fizz Luna #orchid
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So my 11yo kid got injured at a swim meet today right before a race…because some other kid bit him! Still trying to wrap my head around that.
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Brassidium Golden Gamine 'White Knight' #orchid
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Princeton Univ has an excellent opportunity available to start/progress your career in the in-demand field of flow cytometry/FACS. Experienced candidates and recent college grads are encouraged to apply: research-princeton.icims.com…
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I am in love with this massive #dahlia.
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Minor Trizol spill in lab, and sneakers had to be trashed. It’s going to be a fun walk to my car.
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#clematis ‘huvi’ #gardening
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Flight cancelled AGAIN! Stranded in #Phoenix
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Helping to rescue this sick pelican in Santa Barbara might be the most rewarding thing I ever do at a scientific conference.
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Great start to #pridemonth2022 when I have to clarify for the millionth time that I am not, in fact, the nanny 🏳️‍🌈
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