@ProfDMThomas

medical oncologist and clinician scientist

 Australia
Joined May 2014
  • Tweets2.3K
  • Following133
  • Followers1.4K
39Media
Spread the word: precision oncology in action! newscientist.com/article/259… @OmicoAustralia @UNSWMedicine @NSWHealth @CancerAustralia @cancerNSW

Precision oncology: A revolutionary way of targeting tumours could beat even the worst cancers |...

We have long treated cancer based on its location in the body. But a whole new approach that analyses tumours differently is now helping people survive forms of cancer that were once considered a...

newscientist.com
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Corresponds to my experience: AI co-scientists are revolutionizing how research is done nature.com/articles/d41586-0…

AI co-scientists are revolutionizing how research is done

Nature - Artificial-intelligence systems can generate hypotheses, design experiments and analyse data — but humans still need to decide what makes sense.

nature.com
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More than 18,000 questionable images found in antibody catalogues of 15 companies nature.com/articles/d41586-0… Honestly, is anyone surprised?

More than 18,000 questionable images found in antibody catalogues of 15 companies

Nature - Science sleuth’s findings raise questions for researchers working to improve the reliability of commercial antibodies.

nature.com
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Humanity spoke thousands of languages at the dawn of farming — now many of them are lost. Language as a metaphor for cultural diversity? Or even ideas? Read the original article: science.org/doi/10.1126/scie… nature.com/articles/d41586-0…

The rise and fall of language diversity through the Holocene

Characterizing the factors that have shaped linguistic diversity is fundamental for understanding human history, culture, and cognition. In this study, we combined statistical and social computatio...

science.org
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The rise of evidence-based medicine and the ‘mavericks’ who championed it nature.com/articles/d41586-0… A reminder of the critical role of evidence in good medicine.

The rise of evidence-based medicine and the ‘mavericks’ who championed it

Nature - An impeccably researched account describes how clinical trials have transformed health and social policy.

nature.com
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Worse than I feared. British ‘First Fleet’ brought smallpox to Australia—and may have killed millions | Science | AAAS science.org/content/article/…
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Professor DM Thomas retweeted
Vivek Subbiah, MD
@VivekSubbiahMay 25
Wow! Marked reduction of LDL cholesterol with one shot PCSK9 gene base editing 👉🏼In Vivo Base Editing of PCSK9 with VERVE-102 for Hypercholesterolemia | New England Journal of Medicine @NEJM @skathire 👏🏼👏🏼👏🏼 nejm.org/doi/full/10.1056/NE…

In Vivo Base Editing of PCSK9 with VERVE-102 for Hypercholesterolemia | NEJM

Persons carrying loss-of-function variants of proprotein convertase subtilisin–kexin type 9 (PCSK9) have reduced levels of low-density lipoprotein (LDL) cholesterol and fewer atherosclerotic cardio...

nejm.org
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Looking forward to #Nanoporeconf London Calling 2026 @OmicoAustralia @UNSWMedicine
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Does the PSA test for prostate cancer save lives? New data reverse gold-standard findings nature.com/articles/d41586-0…

Does the PSA test for prostate cancer save lives? Gold-standard findings show surprising shift

Nature - Health-evidence reviewers revisit screening for a common cancer, after decades of controversy.

nature.com
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Razelle Kurzrock, MD@Dr_R_KurzrockMay 11
I used to run hairy cell leukemia clinic at MDACC. Who wore it better
Papa Heme
@Papa_HemeMay 10
In my opinion hairy cell leukemia cells are beautiful.
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Peter Mac Cancer Centre@PeterMacCCMay 11
Today, on #InternationalNursesDay, we celebrate the extraordinary nurses at Peter Mac and beyond. Our #nurses provide some of the most specialised cancer care in the world - constantly pushing the boundaries of what exceptional cancer care looks like.
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Peter Mac Cancer Centre@PeterMacCCMay 5
Peter Mac is set to become the first centre to treat a patient under a new PBS-funded CAR T-cell therapy program for multiple myeloma — marking a major step forward for patients with limited options. More: petermac.org/about-us/news-a…
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The Nobel Prize
@NobelPrizeMay 5
”Failure is really important. Experiments don't have to succeed.” Medicine laureate Richard Roberts shares some of his best advice to young students about staying creative, being true to yourself and listening to nature – which can lead to discoveries. Roberts shared the 1993 Nobel Prize in Physiology or Medicine with Phillip Sharp for their discoveries of split genes. Watch the full conversation: bit.ly/4izEe1q
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Vivek Subbiah, MD
@VivekSubbiahMay 3
Living Guidelines for Tumor-Agnostic Therapies: A Pathway to Next-Generation Cancer Treatment | JCO Precision Oncology ascopubs.org/doi/10.1200/PO-…

Living Guidelines for Tumor-Agnostic Therapies: A Pathway to Next-Generation Cancer Treatment | JCO...

Tumor-agnostic therapies represent a transformative shift in oncology, targeting molecular alterations irrespective of cancer histology. These therapies offer new hope for patients with rare and...

ascopubs.org
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Professor DM Thomas retweeted
Vivek Subbiah, MD
@VivekSubbiahApr 30
There’s a Revolution in Cancer. But Can Big Pharma Afford It? Revolution Medicines could soon launch a pancreatic-cancer drug. Its stock may already be beyond what established pharmaceutical firms can pay cc @Aiims1742 @DavidHongMD wsj.com/finance/investing/th…

There’s a Revolution in Cancer. But Can Big Pharma Afford It?

Revolution Medicines’ stock has surged on the promise of a pancreatic-cancer drug. With any deal to buy the firm looking unlikely, investors should be prepared for the long haul.

wsj.com
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Genome pioneer Craig Venter dies: here’s how he transformed science. I can't forget his talk to our Big Ideas seminary series last year. Vale. nature.com/articles/d41586-0…

Genome pioneer Craig Venter dies: here’s how he transformed science

Nature - Venter redrew the boundaries of biology — sequencing DNA at unprecedented speed, engineering synthetic life and charting ocean microbes.

nature.com
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Ben Westphalen@BenWestphalenApr 29
This is a saddening turn in the remarkable story around this manuscript. This paper achieved unseen popular attention and its content was positioned as a new hope for patients with #PancreaticCancer - the lack of transparency is concerning.
Dr. AK 🇮🇳
@docakxApr 28
PNAS retracted Mariano Barbacid’s Dec 2025 paper on a triple therapy (daraxonrasib + afatinib + SD-36) that achieved complete pancreatic tumor regression in 45 mice. The sole reason: undisclosed financial stakes by Barbacid and two co-authors in Vega Oncotargets startup. Scientific findings were not challenged. The authors will resubmit with proper disclosure.
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Suryansh Tiwari
@Suryanshti777Apr 28
A man spends 50 years teaching at MIT. He knows his time is running out. So he records one last lecture — everything he knows, distilled into a single hour. He died 5 months later. This is that lecture. The most important hour you'll watch this week. 👇 Bookmark it for later
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Love this from @Nature briefing this am: Species with longer names — such as Myxococcus llanfairpwllgwyngyllgogerychwyrndrobwllllantysiliogogogochensis (longest ever scientific name) get fewer citations and Wikipedia reads.
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1. Excited to share the first results from @Omico's MoST program (2016-21): overall survival extended from 12.8-21.2 months for well-matched therapies jamanetwork.com/journals/jam…

Genomic Therapy Matching in Rare and Refractory Cancers

This cohort study assesses whether a tiered, evidence-based framework for matching genomic biomarkers to therapies is associated with differential overall survival in patients with advanced solid...

jamanetwork.com
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2. Read @VivekSubbiah commentary here jamanetwork.com/journals/jam… @UNSW

Delivering Precision Oncology at Scale—Infrastructure, Evidence, and the Path Forward

In their study in this issue of JAMA Oncology,1 Lin and colleagues report findings from Australia’s Molecular Screening and Therapeutic (MoST) program. This cohort study examined 3383 patients with...

jamanetwork.com
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