Excited about proteins, membranes, signaling and microscopes
Joined May 2021
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PiehlerLab retweeted
Terrific to write this preview in @CellCellPress with Samantha Joubran on an outstanding paper describing the structure of the THPO-MPL complex and its role in hematopoiesis from the Garcia lab: cell.com/cell/fulltext/S0092…
cell.com/cell/fulltext/S0092…
PiehlerLab retweeted
Now online! Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis dlvr.it/Sv9s81
PiehlerLab retweeted
We, at the Weizmann Institute of Science, are ashamed of, and dismayed by the Israeli government, who is threatening to crush all the conditions for the existence of a healthy civil society, and to act contrary to the law and the court’s order. (1/6)
PiehlerLab retweeted
🍰 Leptin is a hormone that promotes satiety. But how does it give the 'I'm full' signal? Alexandra Tsirigotaki, Kenneth Verstraete, Savvas Savvides, and colleagues @InflamResCen present the 3D structure of leptin as it binds to its receptor to give the signal.
vibbio.tech/42E9sxq
PiehlerLab retweeted
🔬 Drs. @Steven_C_Wilson and Nathanael Caveney (@CaveneyNA) at @StanfordMed used #cryoEM, single-molecule imaging, and cell-based signaling approaches to explore the structural basis for IL-17 family signaling.
📝 @Nature | go.nature.com/3bopPsw
💬 | bit.ly/3d3UFHi
PiehlerLab retweeted
Proud to share the structure of HOPS, a spectacular tethering and fusion complex! Super work by @DmitryShvarev and tw-less Jannis Schoppe and Caroline König. Great collaboration with @UngermannLab and first structure from our Glacios Elenor!
doi.org/10.1101/2022.05.05.4…
#cryoEM #UOS