Excited about proteins, membranes, signaling and microscopes

Joined May 2021
Professorship at UOS in an excellent research environment: SFB 1557 biologie.uni-osnabrueck.de/f…, RTG 2900 cellnanos.uni-osnabrueck.de/… Less than a week left to apply: uni-osnabrueck.de/universita…
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Terrific to write this preview in @CellCellPress with Samantha Joubran on an outstanding paper describing the structure of the THPO-MPL complex and its role in hematopoiesis from the Garcia lab: cell.com/cell/fulltext/S0092… cell.com/cell/fulltext/S0092…
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Our RTG "nanomaterials@biomembranes" made it into the "final 11" - many thanks to the terrific team!
11 neue Graduiertenkollegs #GRK erhalten #DFG-Förderung von rd. 76 Mio. € für Förderperiode ab Herbst 2023. Die Themen reichen von der Entstehungsgeschichte des Universums über die Qualität in der #Gesundheitsforschung bis zur Forschung an Nukleinsäuren. dfg.de/service/presse/presse…
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We, at the Weizmann Institute of Science, are ashamed of, and dismayed by the Israeli government, who is threatening to crush all the conditions for the existence of a healthy civil society, and to act contrary to the law and the court’s order. (1/6)
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PiehlerLab retweeted
🍰 Leptin is a hormone that promotes satiety. But how does it give the 'I'm full' signal? Alexandra Tsirigotaki, Kenneth Verstraete, Savvas Savvides, and colleagues @InflamResCen present the 3D structure of leptin as it binds to its receptor to give the signal. vibbio.tech/42E9sxq
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Leptin receptor assembles into trimers: amazing structural work from the @SavvidesLab! rdcu.be/c8j7c
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reHaloTag labeling: final version is now online: onlinelibrary.wiley.com/doi/…: long-lived, works with traditional HTL dyes and is ideal for single molecule tracking! Happy to share the clones, soon available from Addgene.
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🔬 Drs. @Steven_C_Wilson and Nathanael Caveney (@CaveneyNA) at @StanfordMed used #cryoEM, single-molecule imaging, and cell-based signaling approaches to explore the structural basis for IL-17 family signaling. 📝 @Nature | go.nature.com/3bopPsw 💬 | bit.ly/3d3UFHi
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Proud to share the structure of HOPS, a spectacular tethering and fusion complex! Super work by @DmitryShvarev and tw-less Jannis Schoppe and Caroline König. Great collaboration with @UngermannLab and first structure from our Glacios Elenor! doi.org/10.1101/2022.05.05.4… #cryoEM #UOS
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A tremendous fight from Christoph - first with the experiments, then with the reviewers. Congratulations!
"Diffraction-Unlimited Photomanipulation at the Plasma Membrane via Specifically Targeted Upconversion Nanoparticles" - collaborative article by researchers of @UniOsnabrueck #CellNanOs & @UniJena fal.cn/3j1fx /#NLAR
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Many thanks to @barisch_c, Michael Hensel and Rainer Kurre for another exciting imaging workshop! Beautiful electron microscopy and CLEM from Dominique Soldati-Favre, @EnningaL, and Kay Grünewald - and the cool CLEIM work from Pierre Santucci.
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