@PathologyPat

Product Development New England, Naveris, NavDx, minimal residual disease monitoring in head and neck cancer

Hartford, CT
Joined September 2018
Pat Adams retweeted
This is an extraordinarily dangerous proposal. The White House is playing politics with critical research into devastating illnesses like cancer, Alzheimer’s, and heart disease. Funding for life-saving biomedical research should never– ever– be subject to political litmus tests.
Breaking News: Federal officials are drafting an executive order that would help cement President Trump’s ability to control billions of dollars in scientific grants funded by the National Institutes of Health. nyti.ms/4yhi6RS
16
166
3
464
8,341
A new in vitro system can stimulate the production of cells that resemble human #GerminalCenter B cells, which could assist efforts to study immune responses to #vaccines. Learn more in Science #Immunology: scim.ag/4xtAmqg
3
5
1
25
2,258
🧬 New from the Basu Lab! A new @AHNS infographic explores HPV/p16 discordance in oropharyngeal cancer and current guidelines for confirmatory HPV testing. Prepared by @MollyEHeftNeal and @basulab1. #AHNS #HPV #HeadAndNeckCancer
3
4
132
Pat Adams retweeted
AZT was a massive breakthrough in the treatment of HIV which at that time was a death sentence AZT based therapy went on to save millions of lives RFK Jr rewriting history here
26
123
4
627
4,687
Pat Adams retweeted
No, girls vaccinated with diphtheria/tetanus/pertussis (DTP) vaccine did NOT die at 10 times the rate of unvaccinated girls RFK Jr is wrong AGAIN As he has been for decades, on everything to do with vaccines
62
503
14
2,037
13,850
Pat Adams retweeted
Of all RFK Jr's anti science crap..this for me is one of the very very worst The HPV vaccine is on the way to ELIMINATING CERVICAL CANCER in many countries And he wants to stop it For him..even cervical cancer is better than a vaccine Sick
RFK Jr.: "Gardasil is probably the single worst mass vaccine that we've ever seen. This vaccine targets millions of preteens and teens for whom the risk of dying from cervical cancer is zero. Nobody in their right mind would ever take this vaccine if they actually read the clinical literature." "Death rates in the Gardasil trials were 37 times the death rates for cervical cancer. Children who take that vaccine, the Gardasil vaccine, are 37 times more likely to die from the vaccine than they are to die from cervical cancer. The problem with Gardasil, like most vaccines, is it was never tested against a true placebo, an inert placebo." "And the CDC and HHS say, if you don't test it against a true placebo, it's not science. You have no way of gauging whether the injuries you're seeing from the product are being caused by that product, or whether they're just bad, sad coincidences. The entity that is actually performing the study is, and paying for the study, is Merck." "Merck got to decide which injuries were being caused by Gardasil and which were just bad coincidences. And because it had that power, it just wrote them all off as bad coincidences." "You can do that when there's no placebo, because the injuries they were seeing in the control group, where the girls were getting aluminum neurotoxins, were identical to the injuries they were getting in the Gardasil group." "So they said, well, we don't have to report any of these as vaccine injuries. They were able to license something that is insanely dangerous."
73
520
17
1,899
33,441
🧬 It’s encouraging to see 18F-FDG PET/CT showing strong potential for detecting and staging rare kidney cancers like renal medullary carcinoma, where accurate imaging can make a real difference.
A highly versatile nuclear medicine tracer has once again demonstrated how useful it truly is. In a new study published in JNM, 18F-FDG was found to be highly effective at diagnosing and staging renal medullary carcinoma.
1
1
3
190
Pat Adams retweeted
When conventional methods don’t clearly resolve equivocal findings in HPV+ anal cancer follow-up, ctHPVDNA may offer a reliable alternative. Rafi Kabarriti, MD, shares recent research in an Industry Expert Theater supported by @NavDxTest. Mon Sep 28 @ 3 pm, Blue Theater #ASTRO26 Learn more & add this IET to your schedule: bit.ly/4Aq8u8S
2
5
597
New in Advances in Radiation Oncology: FES-PET for staging newly diagnosed invasive lobular carcinoma Key finding: In a 4-patient case series, FES-PET changed or supported management in all 3 patients who received it. Case 1: occult supraclavicular nodal (SUVmax 3.3) and chest wall avidity (SUVmax 5.4) after NAC and three margin-positive surgeries prompted a 1000 cGy in 5 fraction sequential boost. Case 2: biopsy-confirmed osseous metastases shifted a cT3N3bM0 patient from curative intent to first-line metastatic therapy. Case 3: a negative scan supported proceeding with chest wall RT and RNI. A fourth patient staged with conventional imaging alone went from cT2N1M0 to pT3N3a at surgery. Why it matters: ILC is a known blind spot for mammography, MRI, and FDG-PET. When occult nodal disease shows up before the plan is locked, it changes volumes, dose, and sometimes intent. Important caveat: n = 4, retrospective, selection bias in who got scanned, no systematic comparison with conventional imaging, and short follow-up. The SCL node in case 1 was treated based on tracer avidity without pathologic confirmation. FES-PET is NCCN-supported for recurrent or metastatic ILC, not for primary staging. Bottom line: This is a signal, not a standard. Useful hypothesis-generating data for a real staging gap, but prospective work is needed before upfront FES-PET changes how we stage locally advanced ILC. doi.org/10.1016/j.adro.2026.… @ASTRO_org #RadOnc #OncTwitter #BCSM
4
6
555
The Jackson Laboratory is a wonderful, collaborative place to pursue basic & translational science. On the faculty job market? I strongly encourage you to consider joining us in Bar Harbor, Maine! Apply: go.jax.org/276n55 #JAXresearch #JAXstemcellsdev
1
22
94
6,953
Pat Adams retweeted
Secretory carcinoma of the breast is a rare (<0.2%) low-grade triple-negative carcinoma defined by the ETV6::NTRK3 fusion. 🔬 Key clues: bubbly eosinophilic secretions, S100+, ER/PR/HER2−, and PAN-TRK positivity. Remarkably, it occurs from childhood to older age. #breastpath
5
27
630
Pat Adams retweeted
Among #Medicare beneficiaries with #KidneyFailure, enrollment in Medicare Advantage after the 21st Century Cures Act was associated with lower rates of kidney transplant and new wait-listing vs traditional Medicare. These findings indicate that policy oversight may be needed to monitor access to a high-value treatment as Medicare Advantage enrollment continues to grow among patients with end-stage kidney disease. ja.ma/3TlCodM
2
2
19
6,235
Submit your abstract for an opportunity to present at the Molecular Cytopathology Meeting in Naples #MolCytoPath2026
4
6
395
Pat Adams retweeted
Diagnostic Approach to Sinonasal Small Round Blue Cell Tumors For the initial immunohistochemical evaluation of sinonasal small round blue cell tumors, a screening panel including AE1/AE3, p40, synaptophysin (Syn), SOX10, CD45, CD99, and desmin may be employed to assess epithelial, neuroendocrine, neural crest/melanocytic, hematolymphoid, and myogenic differentiation.
🤖 Made with AI
2
20
42
2,016
Nothing to worry about here! We’ve got bigger issues to focus on like…checks notes…chemtrails.
29
49
2
279
4,573
Pat Adams retweeted
Geomosaic: a flexible bioinformatics platform integrating complementary metagenomic analyses from sequencing reads to genomes biorxiv.org/content/10.64898…
1
13
29
2,155
Pat Adams retweeted
Do you have a passion for pediatric cancer biology? We are looking for a researcher. This person will work with post-doctoral fellows and scientists to coordinate and manage ongoing mouse experiments. Come join us at St. Jude! Apply here: stjude.wd1.myworkdayjobs.com…
3
3
331