Rachid retweeted
Immunohistochemistry is not always specific to one thing! Here’s a good reminder that SSTR2A is also a neuroendocrine marker, staining Islets of Langerhans in the control tissue. #IHC #Immunohistochemistry #Pathology #PathX #Pathtwitter
Rachid retweeted
The rare HSIL cells - "elusive, inconspicuous and diagnostically unforgiving". (ThiPrep PAP test)
Rachid retweeted
“Pseudo–signet ring cells in ascitic fluid: a deceptive look that can lead you straight to the wrong diagnosis.”
Hydropic degeneration is known to occur in histiocytes and mesothelial cells.
(Cytospin preps)
Rachid retweeted
Cytomegalovirus infection - a Postmortem Lung specimen.
💫 Large, ovoid or pleomorphic nucleus. 💫basophilic,intranuclear inclusions called Cowdry bodies, surrounded by a clear halo( arrow).
💫 Coarse , red intracytoplasmic granules.
💫ancillary tests - CMV-IHC , DNA PCR.
Rachid retweeted
To kick off the month of #February, this might at first glance look like an innocuous section of cerebral cortex, but look more closely. What's the mystery immunostain? What's the diagnosis? #pathology #neuropath #PathTwitter
Rachid retweeted
we know that upper tract uro ca/tissue can be PAX8 positive as a pitfall, but we're seeing more lower tract uro ca/tissue also PAX8 positive!
even with different PAX8 clones!
☑️PMID: 41823017
just FYI!
Rachid retweeted
New article out now #AIMMhighlights
▶️CD30 and Cyclin D1: 100% positive and OCT2: 90% positive in RDD
▶️ Helpful IHC panel for distinguishing RDD from LCH, IMT & IgG4-RD
Clinicopathological Features and Expression of CD30, OCT2, and Cyclin D1 in Rosai-Dorfman Disease: A Retrospective Case Series ovid.com/10.1097/PAI.0000000…
Rachid retweeted
🧩 Bladder riddle
Sheets of cells with this classic morphology.
The patient’s gender matters.
What are your working diagnoses?
#DxMindMap #BladderPath #GUPath #Mimicker #PathTwitter @JHUpath
Rachid retweeted
🧩 Prostate riddle
TURP chips. 🤔
This lesion has a well-known twin sister in the breast.
What is your diagnosis?
#DxMindMap #ProstatePath #GUPath #PathTwitter @JHUpath
Rachid retweeted
Extramedullary Hematopoiesis in Sentinel Lymph Node 🕵️🔬
Rare foci of erythroid, myeloid, and megakaryocytic precursors within a lymph node, representing extramedullary hematopoiesis rather than isolated tumor cells.
#PathX #PathTwitter #breastpath
Rachid retweeted
Benign thyroid inclusions in lymph nodes
✅Uncommon, incidental. Central compartment finding.
✅Small, bland follicles without PTC-type nuclear features.
✅The pitfall? Calling intranodal thyroid follicles metastatic PTC.
✅The counter-pitfall? Missing a tiny PTC metastasis.
Rachid retweeted
Don't confuse fat atrophy with liposarcoma. In the low magnification image, the lobulated pattern (arrow) supports the diagnosis. The patient was emaciated and ill.
Rachid retweeted
"Bags of polys" - GYN PAP test with EMB confirmed (FIGO I) endometrial adenocarcinoma. (ThinPrep)
Rachid retweeted
An unusual case - sclerosed solitary fibrous tumor forming a large bladder mass. An uncommon tumor in a rare site. #UMiamiPath
Rachid retweeted
A fascinating and exceptionally rare case: Hairy Cell Leukemia presenting as a breast mass.
40yo F with a suspicious lesion on mammography was found to have a B-cell neoplasm with classic immunophenotype: CD20+, TRAP+, BRAF V600E+
Thank you Dr. Tsvetnov & UNIM! @BloodPortfolio
Rachid retweeted
CC380. Two recent FNAs of large lymph nodes. Both are women with no relevant history
A. Left, supraclavicular
B. Right, axillary
One is a lymphoma. Answer the test below. This nice paper by Elena Vigliar may be of help doi.org/10.1111/cyt.13455 @DrBMcGinn
