A glimpse into the future!
This week’s Paper Club is all about alternative compute.
Modern AI has been shaped by a tight coupling between transformers, backpropagation, and GPUs. But as compute efficiency starts to plateau, there may be very different ways to build the machines that come next.
We explore what AI compute could look like beyond conventional digital hardware through optical systems that use light to perform computation, neuromorphic architectures inspired by the brain, and experiments teaching living brain cells to play Doom.
00:07 — @FrancoisChauba1: Why Alternative Compute?
03:38 — Beyond Backpropagation
08:08 — Zero-Order Optimization and SOMA
15:06 — Ilker Oguz: Computing With Light
19:27 — Why Optical Computing Isn’t Everywhere Yet
22:23 — Building a Diffusion Model With Light
30:03 — Optical Computing Q&A
39:00 — @AlokVasudev: What Is Neuromorphic Computing?
45:23 — What the Brain Can Teach Us About Chips
49:35 — Where Neuromorphic Computing Stands Today
54:24 — Neuromorphic Computing Q&A
1:04:24 — @vytalow: Teaching Brain Cells to Play Doom
1:07:48 — Training Biological Neurons With Reinforcement Learning
1:12:28 — How Brain Cells Learn From Feedback
1:15:40 — Biological Computing Q&A
Parasma retweeted
From floating reactors to brain chips: VCs picked their favorite YC startups from the summer batch.
spr.ly/6016BGPi5K
Parasma Founder & CEO @vytalow, who previously went viral for training human brain cells to play Doom, says that using them for compute could be far more energy-efficient than today's silicon chips.
"Regardless of how efficient we make silicon, we still haven't solved the efficiency aspect of it, in terms of power efficiency."
"I think human brains are extremely power efficient in comparison to silicon."
"There are things that we can harness [with human brain cells] on top of other stuff like sample efficiency and continual learning."
Introducing Parasma.
Previously, we trained human brain cells to play Doom.
Now, we trained them to predict words in a sentence. We are unlocking human brain cells for compute.
Learn more here: parasma.com/news/human-brain…
@ParasmaAI
hiring an intern @ParasmaAI
- provably brilliant at information theory
- strong at RL
- excited about training brain cells
if ur a furry, neurodivergent, or have something unique to add please apply
point form, 60 words max, email careers [at] parasma [dot] com
Come work for us!
ycombinator.com/companies/pa…
Join us!
i am hiring a research scientist @ParasmaAI starting at $1M + 1% equity.
parasma's mission is to train human brain cells for compute and apply what we learn more generally to biology
if you want to change the world with us, send something about yourself, email me or apply below









