Assistant Professor @UPMCHillmanCC | @DamonRunyon Dale Frey Scientist | microbiome & immunotherapy | follow your gut | she/her/hers | views are my own

Pittsburgh, PA
Joined April 2010
Overacre Lab retweeted
💡 What sets the size of a germinal center? — why lymphatics of course 😉 Our new study with Carla Nowosad reveals how lymphatic remodeling constrains germinal center growth and shapes the quality of the antibody response. @ImmunityCP @nyugrossman cell.com/immunity/fulltext/S…
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Overacre Lab retweeted
Announcing the launch of the Mario Lemieux Microbiome Innovation Center at @UPMCHillmanCC & @PittTweet! Through a $5M commitment from the Lemieux Foundation, matched with an additional $1M from UPMC, this center will advance microbiome research. Read more: mariolemieux.org/microbiome-…
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Overacre Lab retweeted
WTH is wrong with Russ Vought!?! Some personal vendetta against NIH and biomedical research? He is slowing scientific progress, massively undermining our global competitiveness, and because of him, we will have fewer new therapies for disease nytimes.com/2026/09/20/scien…
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Overacre Lab retweeted
Stellar viewpoint from Ira on the current status of cancer immunotherapy - takeaway message: small biotech and academia will need to continue to keep the candle lit for immuno-oncology, and more mechanistic studies will be needed to find the next big thing nature.com/articles/s41577-0…
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Announcing the 2026 #SITC election results! Thank you to all of the candidates for their interest in serving the society, and to the members who voted. sitcancer.org/get-involved/2… #immunotherapy #cancerIO
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Overacre Lab retweeted
Dearest gentle reader, we are delighted to announce a new story from our lab published in @Nature describing how a meal's systemic metabolic changes are interpreted by your immune system to enhance adaptive immunity. A thread 1/ nature.com/articles/s41586-0…
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Congratulations Dr. Finn, an amazing immunologist who continues her research on vaccines at UPMC Hillman & the University of Pittsburgh! @pitt_immunology @PittHealthSci @UPMCnews @UPMCPhysicianEd
It was an absolute honor to introduce Dr. Olja Finn as she received the AAI Distinguished Mentor Award @ImmunologyAAI this year. Olja, you are a pioneer in science, mentorship, and life. 👏💕💜 #IMMUNOLOGY2026 @UPMCHillmanCC @PittTweet
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Congratulations to Drs. Dario Vignali @Vignali_Lab and Sarah Gaffen (@PittDeptofMed, @PittRheum) on being recognized as 2026 Distinguished fellows yesterday at @ImmunologyAAI #IMMUNOLOGY2026!
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Next up in our trainee spotlight series is Katelyn Wolfgang (@Kate_Wolfgang), a graduate student in the @OveracreLab who studies how a commensal gut bacterium drives the formation of tertiary lymphoid structures in the colon: immunology.pitt.edu/news/tra…
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New paper in @NatureMicrobiol. Spatial RNA mapping of microbiome and host. In situ polyadenylation is the key idea. More to come on this. Thank you @NIH and @weandmecfs. nature.com/articles/s41564-0…
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On the latest Outperform Cancer podcast, @OveracreLab chats with @marybethgilliam about her new research showing that the artificial sweetener #sucralose weakens #immunotherapy effectiveness by disrupting the #microbiome outperformcancer.com/podcast…
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When asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018. Read more on #STEMSTEAMDay: scim.ag/48YwNzI @NewsfromScience
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The November issue of @CD_AACR is now online! The cover features work by @diwakardavar, @OveracreLab, and colleagues providing evidence that sucralose consumption ablates cancer immunotherapy response through microbiome disruption - read that and more: aacrjournals.org/cancerdisco…
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Science is not a contest to be won. It’s a collective pursuit of truth that evolves with evidence - not a debate settled by opinion or the loudest voice.
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Overacre Lab retweeted
Regulatory T cells, the immune cells at the centre of Monday's Nobel Prize, are showing promise as a treatment for autoimmune diseases, cancer, and even organ transplants go.nature.com/3WqNNab
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We have people in power making broad claims around certain drugs and autism that have been continuously disproven. The degree to which those comments can undermine public health, do harm to women who are pregnant, create anxiety for parents who do have children who are autistic – is violence against the truth.
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ICYMI: Good news! The House rejected the proposed 40% NIH funding cut. The bill released has NIH funded at $48 billion, almost identical to the Senate’s number of $48.7 billion.
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(Please RT/like/share) We are hiring for the lab @VersitiResearch! Technologist I/II ads live and capacity for a postdoc. For all those who love tissue-resident immunity! Please feel free to reach out or to recommend a colleague. (Not posting links here to avoid spam)
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After study section, before scores are released.
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