Developing computational methods for biomedical research at @TampereUni with the lead of prof. Matti Nykter.

Tampere, Suomi
Joined March 2018
Our investigation into the prostate tumor microenvironment is now out in Nature Comms: nature.com/articles/s41467-0… We combined publicly available scRNA-seq data with in-house spatial transcriptomics samples to jointly anayze data from 120 patients. Here’s what we found 🧵 1/6
1
6
3
15
3,247
Communication is important even at the intra-cellular level. @SiniHakkola @NykterLab explains its role in cancer development in our latest blog post: tumorgenetics.blog/2024/05/0…
2
5
2,177
Could club cells be the key to understanding prostate cancer therapy resistance? We performed integrative analysis on single-cell & spatial transcriptomics data from more than 100 patients. Preprint out now: biorxiv.org/content/10.1101/…
2
3
11
5,643
Congratulations to Ebrahim Afyounian and Thomas Fleischer @TF_82 for a good defence on Friday! We had a wonderful evening celebrating the closing of Ebrahim’s journey to PhD @NykterLab. 🥰
1
6
1,324
Nykter Lab retweeted
Our new study shows that immunological pathways differ in different subtypes of #type1diabetes and the involvement of #enteroviruses in the initiation of the process.  go.nature.com/3Rdg5U2 Privileged to work with the talented people from the @NykterLab and @RautajokiLab 🙏
8
2
28
2,899
New blog out: “What are scientific studies made of?” by Lauri Ryyppö of @NykterLab tumorgenetics.blog/2023/06/1…
1
5
2,075
Another @Prostatakreft #blueribbonpin has been appointed for #prostatecancer #research! Congrats Dr Sinja Taavitsainen (lnkd.in/d7M9j4TJ) for the brilliant defence vs @jweischenfeldt . Supervision of Prof. #MattiNykter @NykterLab #Tamperepcrc @TampereUniMET @TampereUni
2
1
15
2,695
Today we had a great recreational day at #Ahtialanjärvi with @NykterLab, building nesting boxes for endangered bird species and observing some birds.
1
6
972
PhD students Tuomo Virtanen and Antti Kiviaho presenting their posters at #AACR2023. Come to talk about our work on chromatin conformation and spatial transcriptomics in prostate cancer.
1
7
674
Replying to @CoEinTG
@CoEinTG Fascinating updates and important discussions at the SAB (Scientific Advisory Board) meeting of the Centre of Excellence in Tumor Genetics today. Tomorrow we will continue with workshops to discuss further and deepen our collaborations. #cancerresearch
3
5
764
Here’s our @Nature paper on v deep whole-genome sequencing of serial ctDNA and met tissue. @cherberts1, Matti, Joonatan et al applied new methods to give fascinating insight into temporal #ProstateCancer clonal complexity and evolution of resistance. 1/7 nature.com/articles/s41586-0…
44
173
25
628
Large grant recipients Steve Bova and Matti Nykter are reverse engineering the evolution of aggressive prostate cancer. The results can help develop new cures for prostate cancer. sigridjuselius.fi/en/news/st… @NykterLab @TampereUniMET @TampereUni #EWAC2022 #cancer
3
1
21
Long anticipated #snogfibtra2022 symposium ongoing in Helsinki. Three days of presentations on exciting top level neuro-oncology research. @Granberg_Lab @TampereUni
2
13
Nice discussion about prostate cancer and emerging treatment options in MTV Uutisaamu this morning. Thanks for invitation and this opportunity @MTVUutisaamu @Syopasaatio
2
2
27
Very excited to receive @SuomenAkatemia funding to continue studying human microglia in neurodegeneration! Big thanks to my mentors @zauggj @HiltunenLab and of course the members of the labs, and I look forward to continuing this field of research in @NykterLab @TampereUni
6
5
3
50
Prostate cancer research center seminar ongoing at Murikanranta. Two days of presentations and discussions on our ongoing work. @TampereUniMET
2
22