Prof. Mikko Hiltunen's research group investigating #Alzheimer's Disease at @UniEastFinland; Director of UEF Neuroscience Research Community
Kuopio, Finland
Joined September 2017
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Congratulations to Heli Jeskanen, who just won the best poster award related to PMG-AD project in the JPND meeting at Brussels! @UEF_Biomed @UEFNeuroInno @UEFneuroscience
Please check our latest findings related to effects of PLCG2 variant on AD pathology @UEFneuroscience @SuomenAkatemia Protective variant in PLCgamma2 mitigates Alzheimer's disease associated pathology via enhancing beneficial microglia functions biorxiv.org/content/10.1101/…
Excellent collaboration with Maria Jose Diogenes group! A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's disease: Molecular Therapy cell.com/molecular-therapy-f…
Outstanding funding decision for UEF Neuroscience Research Community!@UEFneuroscience @kuo_brain_mind uef.fi/en/article/eu-funding…
Hiltunen Lab retweeted
Pioneering study identifies six genetic regions associated with normal pressure hydrocephalus. Published in Neurology, the study is the first large-scale genome-wide association study related to NPH in the world. @GreenJournal @UEFneuroscience @KuopioNPH uef.fi/en/article/pioneering…
Hiltunen Lab retweeted
Uraauurtava tutkimus tunnisti kuusi normaalipaineiseen hydrokefaliaan liittyvää geenialuetta. Kyseessä ensimmäinen laajamittainen koko genomin kattava tutkimus NPH-taudista maailmassa. @UEFneuroscience @Pshyvinvointi @HiltunenLab @KuopioNPH @ClinmedUef uef.fi/fi/artikkeli/uraauurt…
Six novel gene loci identified in normal pressure hydrocephalus! @KuopioNPH @SuomenAkatemia @FinnGen_FI @UEFneuroscience Risk Variants Associated With Normal Pressure Hydrocephalus | Neurology neurology.org/doi/10.1212/WN…
Comprehensive discussion in Nadine Huber’s PhD dissertation - Nadine is doing great!😊 @HaapasaloLab @HiltunenLab @UEF_Biomed @UEFneuroscience
Cross-sectional study of plasma phosphorylated Tau 217 in persons without dementia medrxiv.org/content/10.1101/…
Hiltunen Lab retweeted
📢Publication of the first study investigating how genetic factors influence changes in neuroimaging markers during a 2-year multidomain lifestyle intervention
Congrats to the authors👏
@drsaadmaan @HiltunenLab @TiiaNgandu @HilkkaSoininen @MiiaKivipelto
alz-journals.onlinelibrary.w…
Hiltunen Lab retweeted
Apoe4-tuplageeni ei aina aiheuta muistisairautta, vaikka lisääkin riskiä. Elintavat vaikuttavat, sanoo Mikko Hiltunen @kuo_brain_mind @UEFneuroscience @UniEastFinland @HiltunenLab @Kuopionkaupunki hs.fi/tiede/art-200001042546…
Hiltunen Lab retweeted
A new preprint from Mikko Hiltunen's group utilises FinnGen to show that the Finnish TYROBP deletion associates with an increased risk and earlier onset of dementia and Alzheimer’s disease in the monoallelic carriers.
Happy to share our recent preprint Monoallelic TYROBP deletion is a novel risk factor for Alzheimer's disease medrxiv.org/content/10.1101/… - Thanks to Henna and all other co-authors! @SuomenAkatemia @SigridJuselius @JPNDeurope @UEFneuroscience @UEF_Biomed
Happy to share our recent preprint Monoallelic TYROBP deletion is a novel risk factor for Alzheimer's disease medrxiv.org/content/10.1101/… - Thanks to Henna and all other co-authors! @SuomenAkatemia @SigridJuselius @JPNDeurope @UEFneuroscience @UEF_Biomed
Hiltunen Lab retweeted
The #alzheimersdisease risk gene PLCγ2 acts in neurons as well as microglia, maintaining synapse number and excitability. @PasteurLille ow.ly/NnqW50RASxy
Great collaboration with Lambert lab - Neuronal downregulation of PLCG2 impairs synaptic function and elicits Alzheimer disease hallmarks biorxiv.org/content/10.1101/…
Hiltunen Lab retweeted
Kansainvälinen @alzassociation myönsi Neurotieteiden tutkimusyhteisön tutkijoille merkittävän rahoituksen hankkeeseen, jossa tutkitaan Alzheimer-riskiin liittyvien TMEM106B-geenimuutosten vaikutusmekanismeja. @UEFneuroscience @HiltunenLab @LabMalm uef.fi/fi/artikkeli/merkitta…
Hiltunen Lab retweeted
@KuopioEpilepsy Workshop panel discussion on Biomarkers for Epilepsies and Neurodegenerative Diseases with Valtteri Julkunen (@FinnGen_FI), @rkalviainen, @HiltunenLab and Susanne Bäck (@CRiverLabs)
Hiltunen Lab retweeted
"Dementia is not one specific disease, instead it is an overarching term describing a group of diseases characterized by progressive cognitive decline, associated with degeneration of brain matter."
Find out more by reading the post written by our PhD researcher Elena Ppali 🧠
Let’s talk dementia!
🔵What is ‘Dementia’?
🔵What are the symptoms?
🔵How many types of Dementia exist?
Read Elena Ppali's post to find out!
sites.uef.fi/neuro-innovatio…
#dementia #dementiaawareness #brainhealth #msca #horizon2020 @UEFneuroscience @HaapasaloLab
