@NMSBlab

The main research goal in Krieg's lab is to understand cell mechanical properties for health and disease on the molecular and systems level using C. elegans

 Castelldefels, Spain
livinglight.icfo.eu/
Joined November 2018
  • Tweets193
  • Following196
  • Followers198
21Media
Interested in building neuronal networks? Bioluminescence and optogenetics? Microfluidics? 👇
Rabbs@Rabbs207 Apr 2023
Check out our latest work from @NMSBlab! Thanks to everybody who made this possible! @Adriana11340914, @neusanfeliu, @NawaphatMalaiw1, @LuiFelMorCur, @Shadi2Karimi, @olapi314 and some more!
5
811
Thank you for having us! Looking forward to meeting you tomorrow!
xavier salvatella@xsalvatella18 May 2023
Very much looking forward to hosting @NMSBlab !
2
398
And read the Research Briefing on this work, here: nature.com/articles/s41592-0…
1
4
10
2,799
In the PhAST technology, light serves as a synthetic neurotransmitter, by combining a calcium-dependent luciferase on pre-synapses with channelrhodopsin on post-synapses, which is illustrated in C. elegans. @NMSBlab nature.com/articles/s41592-0…
1
11
5
27
11,102
Enjoy your summer with a new preprint from the lab with @Rabbs, Adriana and many others: Deploying photons for communication within neuronal networks. biorxiv.org/content/10.1101/…

Deploying photons for communication within neuronal networks

Deficiencies in neurotransmission lead to neurological disorders or misinterpretation of perceived threats. To restore defects in cellular communication, we developed a synthetic, photon-assisted...

biorxiv.org
2
3
3
4
more replies
It was a fantastic and exciting rollercoaster that got ignited 7 years ago on a lab trip with @wormsenselab, canoeing in Tomales Bay and collecting marine, bioluminescent memories. Thanks to all coauthors involved and colleagues for their illuminating discussions, and reagents.
1
1
1
Tweetorial☝️. Uncut and final version now online 👇. Substantially improved presentation and more case examples of luciferases and channelrhodopsins with different colors, applied to two more circuits, the AWA olfactory and the egg laying circuit. rdcu.be/c9kF2
1
1
165
We are thrilled to share our story on deep learning- enhanced #bioluminescence #microscopy published in Comms biology! @CommsBio nature.com/articles/s42003-0… A huge congrats to @LuiFelMorCur and all co-authors from @NMSBlab, @ICFOnians #SLNgroup and @CRGenomica ... 1/6

Volumetric imaging of fast cellular dynamics with deep learning enhanced bioluminescence microscopy

Communications Biology - Bioluminescence microscopy with deep learning enables subsecond exposures for timelapse and volumetric imaging with denoising and yields high signal-to-noise ratio images...

nature.com
2
6
4
26
more replies
We employ deep learning to enhance the SNR of bioluminescence images in HeLa cells, mouse embryonic stem cell colonies, whole zebrafish embryos and whole C.Elegans body wall muscles and even single neurons ... 5/6
1
2
Finally, we push the system to obtain real time 3D reconstruction of low photon samples via light field microscopy by combining 2 neural networks to show that bioluminescent samples can be imaged and de-noised in 3D in a manner comparable to fluorescence microscopy ... 6/6
1
Very nice work and awesome collaboration. Looking forward to what comes next :)
Meital Oren-Suissa@MeitalOren14 Nov 2022
New paper alert! now in @NatureComms, @HagarSetty ’s cool work on sex differences in Mechanosensation. a fun collaboration with @NMSBlab and @Shadi2Karimi nature.com/articles/s41467-0…
7
We are hiring! Interested in doing your PhD in mitochondrial biology in Munich, and curious about how cells distinguish intact from mutant mtDNA? Please apply through our graduate school lsm.bio.lmu.de/. #PhD #CellBiology #mitochondria

Graduate School Life Science Munich (LSM)

LSM Graduate School Munich offers an international doctoral programme in biochemistry, cell biology, genetics, human biology, bioinformatics, molecular biology, microbiology, neuroscience, plant...

bio.lmu.de
1
99
3
187
Great location, great people, great science.
Margarida M Barroso@barrosolab12 Oct 2022
#SHIFT22 at the vulcano! @HenriquesLab @NMSBlab
1
3
If you are at Embl this week for #EESPhaseSeparation, stop by @neusanfeliu’s poster and learn about what large titin and stomatin homologs have to do with your favorite biological process and neuronal mechanotransduction.
Neus Sanfeliu Cerdán@neusanfeliu9 May 2022
Excited to be at the #EESPhaseSeparation Conference at #Embl. Do you want to hear about LLPS role in mechanosensation? Come to visit our poster #136 @NMSBlab @ICFOnians
3
7
Part 2 of @_mlechha's #TwitterTakever of @zhenlab_Toronto. As promised, here's a first thread about the history of the science of animal movement. 1/n
1
3
1
6
Great work by @DasraviDas et al. Check it out now in @ScienceAdvances
Ravi Das@DasraviDas18 Sep 2021
Fresh from the oven: I am very excited to share our recent paper. Special thanks and congratulations to everyone involved:@LuitgardLin @fedcat_131 @NawaphatMalaiw1 @neusanfeliu @Rabbs20 Aleksandra Pidde & Michael Krieg @NMSBlab @ICFOnians #mechanobiology science.org/doi/10.1126/scia…

An asymmetric mechanical code ciphers curvature-dependent proprioceptor activity

Functional compartmentalization of sensory axons by mechanical compression and extension tunes neuronal activity in C. elegans.

science.org
1
4
Fresh from the oven: I am very excited to share our recent paper. Special thanks and congratulations to everyone involved:@LuitgardLin @fedcat_131 @NawaphatMalaiw1 @neusanfeliu @Rabbs20 Aleksandra Pidde & Michael Krieg @NMSBlab @ICFOnians #mechanobiology science.org/doi/10.1126/scia…

An asymmetric mechanical code ciphers curvature-dependent proprioceptor activity

Functional compartmentalization of sensory axons by mechanical compression and extension tunes neuronal activity in C. elegans.

science.org
3
5
3
17
Here we go: An asymmetric mechanical code ciphers curvature-dependent proprioceptor activity science.org/doi/10.1126/scia…

An asymmetric mechanical code ciphers curvature-dependent proprioceptor activity

Functional compartmentalization of sensory axons by mechanical compression and extension tunes neuronal activity in C. elegans.

science.org
2
6
2
12
more replies
3. proprioceptor activity peaks under neuronal compression in vivo (rather than stretch) 4. how K2P and TRP channel are involved to shape neuronal responses to steep membrane tension gradients (both positive and negative).
1
Congratulations to @DasraviDas @LuitgardLin @fedcat_131 @NawaphatMalaiw1 and all others involved. Thanks to everyone who helped and contributed in any way of funding, discussing and sharing reagents ... and now reading. #worms
1
3
Load more