@MuenchLab
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Professor @goetheuni Biochemistry, proteomics, cell and systems biology of proteostasis and cellular stress responses in ageing and disease @cmunch.bsky.social
Frankfurt, Germany
Joined November 2019
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I am happy to propose a model for mammalian #mitochondria UPR signaling, published @Nature.
nature.com/articles/s41586-0…
Mito protein misfolding induces two cytosolic signals –mtROS and mito protein precursor accumulation. These activate the mito UPR via a DNAJA1-HSF1 signaling axis.
Christian Münch retweeted
We’re delighted to welcome Prof. Christian Münch (@MuenchLab) as a speaker at Horizons in Molecular Biology 2025!
He explores protein aggregation, cellular quality control, and the mitochondrial unfolded protein response.
👉 Register now: bit.ly/4j5kioh
#Horizons2025
Christian Münch retweeted
A meeting you don`t want to miss! Deadline for early (discounted) registration, award nominations and abstract submission will be next week, March 5! More info here: pcvb2025.de
🚨Registration is now open for the SFB 1531 | GfMVB International Meeting on Perspectives in Cardiovascular Biology in Frankfurt, April 2025! We are proud to welcome so many outstanding speakers - more info and registration at pcvb2025.de Join us and secure your spot!
Christian Münch retweeted
🚨Registration is now open for the SFB 1531 | GfMVB International Meeting on Perspectives in Cardiovascular Biology in Frankfurt, April 2025! We are proud to welcome so many outstanding speakers - more info and registration at pcvb2025.de Join us and secure your spot!
Looking for exciting opportunities? 🎓 Apply for PhD positions in my lab and others in this fantastic program! 🚀
If you're seeking a postdoc or senior lab scientist role, feel free to DM or email me. Let's connect!
@imprs_cbp #PhDPositions #PostdocJobs
Wrapped up our first Symposium on Advances in Therapeutic Approaches! 🎉 Huge thanks the speakers and extra kudos to our very own @Thatmassspecguy for unveiling our innovative #proteomics data to profile E3 ligase & #PROTAC targets. 🔬✨
#TheraNova @proxidrugs @EnableFrankfurt
What a great joy to meet up with the PROGENIE group to discuss the future of #proteostasis and all the topics of new and not-anymore-so-new PIs. Loved the Xmas crackers 😀
Join us next time if you are a new PI in Europe working on proteostasis, check 👉molsysmed.de/project/proteos…
Today marks 8 years @goetheuni-an incredible journey from group leader @IBC2_GU to now 🥳full professor & Director of the Institute of Molecular Systems Medicine in Frankfurt. Grateful for the invaluable support and amazing people along the way! @EMBO_YIP, @ERC_Research
Thank you to:
@VolkswagenSt, Johanna Quandt, Alfons & Gertrud Kassel, and Dr. Rolf M. Schwiete Foundations for establishing an endowed chair, and to
@HMWK_Hessen for funding a top professorship.
Grateful for all the incredible support anabling me to pursue my research dreams!
Christian Münch retweeted
Our story on a novel pathway that controls #mitochondria from the 𝐜𝐲𝐭𝐨𝐬𝐨𝐥 and influences #immunity is now peer-reviewed and available at @PNASNews!
pnas.org/doi/10.1073/pnas.24…
By M. Foged @DIB_UNIL @FBM_UNIL @MuenchLab @VamsiMootha #N6AMT1 #mtDNA #RNA_processing
A recap 🧵
Fantastic job by Bhavesh @Thatmassspecguy presenting his recent data on E3s at #HUPO2024
🤩
#proudPI, #proteomics, @proxidrugs
Happy to see the Frankfurt Competence Center for Emerging Therapeutics #FCET taking off - a wonderful initiative with excellent scientists trying to reshape our academic capabilities to push research and early drug discovery.
I am particularly proud to be the founding director.
Starting #Frankfurt Competence Center for Emerging #Therapeutics (#FCET) as part of Go4Tec at
@goetheuni to serve scientists.
Huge thx to many in GU particularly from @IBC2_GU who helped turning this vision into reality... proud 🫶👍☺️
More info: linkedin.com/feed/update/urn…
Great start for #HUPO2024. The Münch lab is there with some of our latest projects. Take a look below and contact us at HUPO (or online) to find out what we are up to.
Welcome to a great new group of IMPRS students. Awesome to see the enthusiasm resulting in great discussions 👍
We had a great start of the Cellular Biophysics symposium to welcome our new IMPRS students. Thank you for your fascinating talks 👏 @DoetschVolker Clemens Glaubitz @MuenchLab @CovinoLab @LemkeLab @maxplanckpress @MPIbp @fias_science @uni_mainz @goetheuni #imprs #imprs_cbp #phd
Christian Münch retweeted
It is still possible to register for the GBM Compact meeting on Imaging in Frankfurt, Sep 26/27. It is almost fully booked but a few seats are still available. Exciting biology and lots to learn about imaging. Great opportunity for networking. @GBM_eV gbm-compact.org/gbm-compact-…
Christian Münch retweeted
In our new study we reveal how NAC coordinates and regulates successive co-translational nascent chain ⛓️ processing on the mammalian ribosome
out today in @Nature rdcu.be/dRAQY
collab with @DeuerlingLab Shu-ou Shan @Caltech
@snsf_ch @ERC_Research @ETH_en
📢Job alert #proteomics expert (postdoc or staff scientist):
want to play with an Orbi Ascend, Lumos, TimsTOF etc in a great team of proteomics enthusiasts?
PM or Email your application
nature.com/naturecareers/job…
Very interesting story from @jourdainlab that provides important new insights into the poorly understood #mitochondria RNA processing. 📢📢📢
Also another great example of our translation and mitochondrial protein import #proteomics in action 😍
New preprint from the lab!
𝗖𝘆𝘁𝗼𝘀𝗼𝗹𝗶𝗰 𝗡𝟲𝗔𝗠𝗧𝟭-𝗱𝗲𝗽𝗲𝗻𝗱𝗲𝗻𝘁 𝘁𝗿𝗮𝗻𝘀𝗹𝗮𝘁𝗶𝗼𝗻 𝘀𝘂𝗽𝗽𝗼𝗿𝘁𝘀 #𝗺𝗶𝘁𝗼𝗰𝗵𝗼𝗻𝗱𝗿𝗶𝗮𝗹 𝗥𝗡𝗔 𝗽𝗿𝗼𝗰𝗲𝘀𝘀𝗶𝗻𝗴
biorxiv.org/cgi/content/shor…
By Mads Foged et al.
A 🎬 and a 🧵
A couple of days left to sign up with early registration and abstract for what promises to be a great conference.
GBM Compact: Focus on Imaging
Frankfurt, September 26-27, 2024
Deadline for early registration and abstract submission: June 30
gbm-compact.org
👇 👇 👇 👇 👇
Great and must read paper from @LabPrudent about mitochondrial fusion. Congrats Julien & colleagues!
Delighted to share the last study of the lab led by the fantastic postdoc @Tabara_LC out in @CellCellPress !!!
We show how MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels.
@MRC_MBU @Cambridge_Uni
authors.elsevier.com/sd/arti…