@LabPrudent

Mitochondrial Dynamics group at Imagine Institute, Paris, France. We study Mitochondrial Cell Biology, Dynamics and Contact Sites. All tweets are from Julien.

 Paris, France
mrc-mbu.cam.ac.uk/research-groups/prudent-group
Joined March 2020
  • Tweets219
  • Following420
  • Followers3K
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Delighted to share the last study of the lab led by the fantastic postdoc @Tabara_LC out in @CellCellPress !!! We show how MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels. @MRC_MBU @Cambridge_Uni authors.elsevier.com/sd/arti…
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🚀 We’re hiring! Join our newly established lab at the @InstitutImagine in Paris 🇫🇷 We’re recruiting: 🧬 2 Postdoctoral Researchers in Mitochondrial Cell Biology 🔬 1 Laboratory Manager Thread below 👇
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👉 Apply for the Postdoctoral positions: welcometothejungle.com/fr/co…

Two (2) Postdoctoral Positions in Mitochondrial Cell Biology - Institut Imagine - CDD / Temporaire...

Institut Imagine recrute un(e) Two (2) Postdoctoral Positions in Mitochondrial Cell Biology à Paris !

welcometothejungle.com
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🔬 Laboratory Manager We’re looking for a scientist with a strong molecular/cell biology background to help run and develop the lab while contributing experimentally to our research. 👉 Apply: welcometothejungle.com/fr/co…
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After 10 fantastic years at the @MRC_MBU, @Cambridge_Uni, it is time for our lab to move to France!! I am delighted to announce that we will begin a new adventure at the @InstitutImagine in Paris in September 2026!!
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We are now looking forward to this exciting new chapter and to continuing our research programme in Paris, investigating mitochondrial membrane remodelling, mtDNA dynamics, and membrane contact sites in health and disease.
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Thank you, Cambridge, and see you soon, Paris! Postdoctoral and Lab Manager positions will be advertised soon. Stay tuned!
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Delighted to share our collaborative review with @LabReuben, @LabGanley and Grahame Hardie, on recent advances in AMPK and mitochondrial life cycle, now out in @TrendsCellBio! Have a read if interested! 👇 cell.com/trends/cell-biology…

AMPK: a master regulator of mitochondrial quality and quantity

The AMP-activated protein kinase (AMPK) may have arisen soon after the endosymbiosis event that generated eukaryotes, perhaps to allow the archaeal host to communicate its requirements for ATP to the...

cell.com
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Great fun writing this @ScienceMagazine Perspective with @Jellevda on the work from @jclandoni , @SulianaManley and colleagues showing how mitochondrial pearling organises mtDNA! Beautiful study and stunning microscopy 👏 science.org/doi/10.1126/scie…

Mitochondrial genomes on a string of pearls

Transient membrane constrictions, or “pearling,” underlie the regular spacing of mitochondrial genomes

science.org
Juan Cruz Landoni@jclandoni
Apr 5
Check out the fantastic perspective by @Jellevda & @LabPrudent on our #pearling work, out in the same @ScienceMagazine issue! science.org/doi/10.1126/scie…

Mitochondrial genomes on a string of pearls

Transient membrane constrictions, or “pearling,” underlie the regular spacing of mitochondrial genomes

science.org
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A bit late to the party, but delighted to share our mini-review on the mitochondrial (mt)DNA life cycle, highlighting emerging mechanisms of mtDNA degradation! Always a pleasure to work with the fantastic @Tabara_LC !! Have a look 👇 nature.com/articles/s41556-0…

Emerging mechanisms of genome degradation during the mtDNA life cycle

Nature Cell Biology - Mitochondrial DNA (mtDNA) is not static but undergoes a regulated ‘life cycle’ that encompasses replication, maintenance, spatial distribution and turnover. Here,...

nature.com
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Congrats Luisca @Tabara_LC 🥳🥳 !! An outstanding scientist joining a fantastic place! So much deserved! Excited to follow the amazing Science you and your team will produce!! 🔥🔥🔥
Luis Carlos Tábara Rodríguez@Tabara_LC
17 Sep 2025
Thrilled to announce my lab launches this October at the amazing @CRG in Barcelona! Ready to tackle the biggest mysteries of mitochondrial dynamics and mtDNA regulation! Job openings coming soon! Please RT!
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Looking forward to this exciting meeting in Malta!! Will be lot of fun with great Science :)
Fusion Conferences@Fusion_Conf
18 Mar 2025
Replying to @LabPrudent
@LabPrudent we are looking forward to your presentation at #IOSCD25 in Malta🇲🇹 Please share with your followers to let them know early bird registration & talk submission close on 01 May! Find out more: bit.ly/IOSCD25_TalkSub
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I’m excited to share the first paper from my lab, out today in @ScienceAdvances! science.org/doi/10.1126/scia… We uncover a new family of phospholipid remodelling enzymes. A 🧵:

TRAM-LAG1-CLN8 family proteins are acyltransferases regulating phospholipid composition

TRAM–LAG1–CLN8 family proteins function as enzymes that remodel cellular phospholipids and expand the membrane lipid diversity.

science.org
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Thrilled to share the last review of the lab led by @Tabara_LC and @MayukoSegawa on the mechanisms regulating mitochondrial morphology!!! @MRC_MBU Just out in @NatRevMCB. Thanks @lisa_heinke for the smooth editorial process!
Nature Reviews Molecular Cell Biology@NatRevMCB
17 Oct 2024
Now Online: Molecular mechanisms of mitochondrial dynamics go.nature.com/405NTaf
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Submit to J Cell Science! A historical journal that cares about our community. They spotlight young "Scientists to Watch", support meetings and travel grants, offer free publication fees, and focus on building community. Mitochondriaks must support them and send us your new work!
J Cell Science@J_Cell_Sci
26 Sep 2024
**Deadline extended to 1 November 2024** Submit your paper for our next special issue: Cell Biology of Mitochondria. Guest edited by Ana J. Garcia-Saez @GarciaSaez_Lab & Heidi McBride @mitodynamics tinyurl.com/mry5cvfs

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Thanks @RobPitceathly for the cool collab! And congrats to Micol, Chiara and @Tabara_LC, and to everyone ! @sollisati ….. 🥳🥳
Robert Pitceathly@RobPitceathly
16 Sep 2024
🚨Advance article alert - mutant PTPMT1 impairs cardiolipin metabolism causing human disease. Fantastic collaborative effort across several continents! Biallelic PTPMT1 variants disrupt cardiolipin metabolism and lead to a neurodevelopmental syndrome academic.oup.com/brain/artic…

Biallelic PTPMT1 variants disrupt cardiolipin metabolism and lead to a neurodevelopmental syndrome

PTPMT1 is crucial for biosynthesis of the signature mitochondrial phospholipid, cardiolipin. Falabella et al. show that loss of PTPMT1 function is associat

academic.oup.com
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My choice this week in @ScienceMagazine @LabPrudent doi.org/10.1016/j.cell.2024.…
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Job Alert! Our lab is recruiting a Postdoctoral fellow to work on the interplay between mitochondrial morphology, mb contact sites, mtDNA dynamics and quality control. Have a look if interested! @MRC_MBU @Cambridge_Uni jobs.cam.ac.uk/job/46901/
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