How do cancer cell microtubules behave in vivo compared to in cell culture? Intravital microscopy showed nearby macrophage signaling can be as much a factor as the 3D extracellular matrix environment, leading to more coherent microtubule alignment. rdcu.be/b5BSM

Excited to share Stephanie’s work on tumor/macrophage feedback via RTKs, esp AXL+MERTK. Thank you to the team incl. Doug, @WeisslederLab @MadeleineOudin Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy advances.sciencemag.org/cont…