Associate Professor at the University of Ottawa, Canada | Metabolism | Mitochondria | Muscular Dystrophy | Aging. Views are my own. (he/him)

Ottawa, Ontario
Joined September 2015
Excited to publish in @LSAjournal! We and the @PlacentaLab show that inflammatory preeclampsia exhibits reduced NAD+ levels and mitochondrial dysfunction in the placenta. Our work suggests that NAD+ boosters during pregnancy may counter these effects. doi.org/10.26508/lsa.2023025…
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We are also very proud of our then PhD student Fahmida Jahan @fjaha037 who led the project and has since moved on to the very well respected lab of @GoodyearLaurie at the Joslin Diabetes Center at Harvard.
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Altered muscle niche contributes to myogenic deficit in the D2-mdx model of severe DMD nature.com/articles/s41420-0…
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Keir Joe Menzies retweeted
Our new resource paper on a novel 🐁 reporter for live tracking of Pax7 and Myf5 expression in #muscle #stemcells A Dual Color Pax7 and Myf5 In Vivo Reporter to Investigate Muscle Stem Cell Heterogeneity in Regeneration and Aging biorxiv.org/content/10.1101/… #myotwitter
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Keir Joe Menzies retweeted
Our work on #healthspan and graceful #aging is featured in @EPFL_en's Dimensions! This huge mouse study would not have been possible without the effort of the entire @Auwerx_Lab team, who relentlessly collected 120'000 tissues in 5-years! link in English: longread.epfl.ch/en/dossier/…
📣 The latest issue of Dimensions, the EPFL magazine, is now available. You can find the print version on campus, and read our longform "Aged, but not old" online: go.epfl.ch/aging
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Congratulations Brayden Perras, Branden Lynch, @A_NikAkhtar and @DheerajPandey_ for presenting your data at the @CSMB2023 conference on Metabolic Regulation of Cell Signalling! Also, shout-out to @AlexEGreen, our postdoc, for your dedication to training each of these students!
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Reducing mitochondrial ribosomal gene expression does not alter metabolic health or lifespan in mice Kim Reid, @EileenD26, @rhhoutkooper, @Menzies_Lab and coauthors. nature.com/articles/s41598-0… @SciReports
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Super proud of lead authors @EileenD26 and Kim Reid for this massive collab with @Menzies_Lab! We started from our 2013 observation that lower mitochondrial ribosomal protein expression extended lifespan in worms, so asked the question: is the same true in mice? ⬇️
The most gratifying work is from seamless collaborations. Thank you to @rhhoutkooper for initiating a project that gave our PhD students Kim Reid and @EileenD26 the opportunity to travel back-and-forth between the Netherlands and Canada.@OISB_IBSO nature.com/articles/s41598-0…
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The most gratifying work is from seamless collaborations. Thank you to @rhhoutkooper for initiating a project that gave our PhD students Kim Reid and @EileenD26 the opportunity to travel back-and-forth between the Netherlands and Canada.@OISB_IBSO nature.com/articles/s41598-0…
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Congratulations to @kwadjonyarko_ who was accepted into the following medical schools: uOttawa, McMaster, UBC and UofT🤩! He has also proven to be a passionate researcher in our lab examining novel post-translational modifications affecting muscle stem cell health. @OISB_IBSO
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Keir Joe Menzies retweeted
Fascinating new preprint on bioRxiv tackles a whale of a question: Whales are huge. So why don’t they get a ton of cancers? biorxiv.org/content/10.1101/…
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🚨 Attention trainees! Application deadline extended until May 19 for #travelawards to attend the ApOC Workshop on Stem Cells & Neural Organoids happening in-person on July 10. Apply today to learn about the generation of neural #organoids from #stemcells: stemcellnetwork.ca/training/…
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Keir Joe Menzies retweeted
Our recent study together with Fabio Penna’s lab demonstrated that vitamin B3, niacin, prevents cancer cachexia in mice. More info in the media release.
Is vitamin B3 a treatment option for human cancer cachexia? A form of vitamin B3, niacin, was found to prevent cancer-related weight loss and muscle wasting, i.e., cancer cachexia, and the underlying mitochondrial alterations in mouse experiments. helsinki.fi/en/news/cancer/v…
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come work in beautiful #losangeles on how #NAD metabolism is disturbed by #DNA damage and #nicotine new BS grad? ✅ new PhD? ✅ we've got great projects for you plus tacos, mountains and beaches pls RT, please get in touch
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Support Our Science Nationwide Walkout is TODAY! This is a protest to @cafreeland & @JustinTrudeau's #budget2023! SOS is advocating for increased federal investments in scholarships, fellowships & grants to support increased pay for grad students & postdocs #SupportOurScience 1/5
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Join me in congratulating our MSc student, and NSERC Create @MMetabolomics Scholar, @DheerajPandey_ who was awarded a Best Poster award at the Biochemistry, Microbiology and Immunology Seminar at the University of Ottawa. Also, special thanks to @AlexEGreen for his mentorship!
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