@MeekLab

Student-run twitter of the Meek Lab at UNC-Chapel Hill. Stereoselectively incorporating boron into molecules and making novel ligands since 2011 👩‍🔬😎👨‍🔬

 Chapel Hill, NC
sites.google.com/view/meeklab/
Joined August 2015
  • Tweets182
  • Following499
  • Followers1.6K
58Media
Enantio- and Site-Selective Synthesis of α-Substituted Hydrazines, Pyrazolidines, and Tertiary Alcohols by Copper-Catalyzed Allylic C–N and C–O Bond Formation | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/jac…

Enantio- and Site-Selective Synthesis of α‑Substituted Hydrazines, Pyrazolidines, and Tertiary...

Abstract. A catalytic method for the enantioselective synthesis of α-tertiary hydrazines, pyrazolidines, and tertiary alcohols containing dialkyl-substitut

pubs.acs.org
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Stereoselective Synthesis of Alkenyl Fluorides and Alkynes by Defluoro Coupling of Trifluoromethyl Arenes (@angewandte): onlinelibrary.wiley.com/doi/… (@MeekLab).
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🚨 Our first Science paper 🚨 We report the isolation and reactivity of the first “inaccessible” 5-membered heteroaryne! 120+ year challenge! Congrats @jennahumke @belli_roman @ErinPlasek @Sal_K_3 @annabelly24 @CortnieRoberts @UMNChemistry @ScienceMagazine science.org/doi/10.1126/scie…

Nickel binding enables isolation and reactivity of previously inaccessible 7-aza-2,3-indolynes

N-Heteroaromatics are key elements of pharmaceuticals, agrochemicals, and materials. N-Heteroarynes provide a scaffold to build these essential molecules but are underused because five-membered...

science.org
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Synthesis of Quaternary and Tertiary Carbon-Substituted Arenes by Lewis Base Promoted Site-Selective Coupling with Allylic Nucleophiles (Simon J. Meek and co-workers) @MeekLab @uncchemistry onlinelibrary.wiley.com/doi/…

Synthesis of Quaternary and Tertiary Carbon‐Substituted Arenes by Lewis Base Promoted Site‐Select...

We disclose a practical method for site-selective allylic coupling that allows the construction of N-heteroarenes containing benzylic quaternary and tertiary carbons from a wide variety of organodi...

onlinelibrary.wiley.com
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ACS Symposium dinner with @santoslabVT @KBrownLab @MeekLab @Hoover_Lab @hull_group Sherry Chemler, Stephen Greszler & Steve Malcolmson. “Advances in Copper Catalysis for Organic Synthesis”
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Get behind the scenes with the folks from our group's cephanolide and ceforalide syntheses in this video from @J_A_C_S! youtube.com/watch?v=5jRwGB8Q…
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Big news out of the Johnson group this week: our most recent publication is now in @ScienceMagazine ! science.org/doi/10.1126/scie… 1/

Doubly stereoconvergent crystallization enabled by asymmetric catalysis

Chiral base catalysis paired with product crystallization can set three adjacent stereocenters in a Michael addition.

science.org
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Excited to share our group’s paper on Sc-catalyzed cross-coupling! What better place for this exciting catalysis research to be than in @ACSCatalysis! 🎉 Way to go @belli_roman, @TafuriTori, @ChicagOChemO and @CortnieRoberts! pubs.acs.org/doi/10.1021/acs…

d0 Metal-Catalyzed Alkyl–Alkyl Cross-Coupling Enabled by a Redox-Active Ligand

Abstract. Alkyl–alkyl cross-coupling through well-defined mechanisms that allow for controlled oxidative addition, prevent β-hydride elimination, and toler

pubs.acs.org
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In my ~element~ 👩🏻‍🔬🧪 Fourth year seminar done! ✅
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Malcolmson-Brown-@MeekLab (MBM) group meetings still going strong! Excellent research talks today by Hawa Keita, Grace Trammel, and Melanie Lee 👏🏻👏🏻👏🏻
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Check out our new group website! sites.google.com/umn.edu/the…

Home

The Chemistry

sites.google.com
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Hey UNC - what happened to conducting Covid surveillance for researchers on campus? It was brought up during Webinar Q&A in May and have not gotten more info since. If we can test athletes, we can test graduate students/employees conducting critical research @UNCResearch @UNC
The Daily Tar Heel@dailytarheel8 Jul 2020
BREAKING: 37 individuals have tested positive for COVID-19 as student-athletes, coaches and staff return to campus, according to UNC Media Relations. Story to come.
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Check out our most recent publication on benzenoid dearomatization in @J_A_C_S ! Congratulations to Kendrick, Cody, and Will! 🍾🎉 pubs.acs.org/doi/10.1021/jac…

Catalytic, Asymmetric Dearomative Synthesis of Complex Cyclohexanes via a Highly Regio- and...

Abstract. Arene cyclopropanation offers a direct route to higher-order, non-aromatic carbocycles; however, the inherent issue of dictating site selectivity

pubs.acs.org
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Congratulations @KevinGuskiewicz for removing the prefix "interim" from your title as chancellor!
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Congratulations to Dr. @Jess_Griswold on her recent Johnson group publication! These lactones presented some interesting challenges and Jess did a great job overcoming them and applying these substrates in a DKR. Check it out in the ASAPs @ACSCatalysis! pubs.acs.org/doi/10.1021/acs…
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Our latest paper on manganese-catalyzed hydroxymethylation has been accepted to Org. Lett. @JOC_OL and is now available online. Congratulations, Hannah! pubs.acs.org/doi/full/10.102…
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Get ready to put on your PPE because Robert’s Lab is up and running! Peep the trailer made by @KwongBailey!
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Check out our explosive(ly safe) method for the hydroazidation of activated olefins! thieme-connect.de/products/e… Congrats to @nicholasonuska, @meschutzbach, and José! 🍾
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Excellent work from Andrew, Bijan, Alexa, Liher and Jon! Check our their newest work on the enantioselective Cu-catalyzed synthesis of boryl-functionalized cyclobutanols! See it here in the ASAPs: pubs.acs.org/doi/10.1021/acs… @ACSCatalysis
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Catalytic Enantioselective Synthesis of 1,4-Keto-Alkenylboronate Esters and 1,4-Dicarbonyls (Meek) doi.wiley.com/10.1002/anie.2…
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