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🔥 GASTROESOPHAGEAL REFLUX DISEASE (GERD)
⚠️ GERD = symptomatic reflux of gastric contents into the esophagus
➤ Most commonly due to transient LES relaxation
➤ Contributing factors: incompetent LES, gastroparesis, hiatal hernia
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❤️ Heart Failure (HF)
1️⃣ Types
🔹 HFrEF (Reduced EF <40%) → Systolic dysfunction → Dilated ventricles
🔹 HFpEF (Preserved EF ≥50%) → Diastolic dysfunction → Stiff ventricles
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🫀 INFECTIVE ENDOCARDITIS
⚠️ Risk Factors
• Prosthetic valves & valvular heart disease
• Cardiac devices, congenital heart disease
• IV drug use
• Poor dentition / dental procedures
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Approach to COMA
Decreased Consciousness, Nonresponsive → Coma exam → GCS & CNs exam
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🔍 Step 1: Assess for Cause
⚠️ Rule out systemic causes of AMS
→ Refer to AMS (Altered Mental Status) protocols
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1️⃣ If Preceded by Trauma → Do Non-contrast Head CT
🔴 Epidural Hematoma:
•Biconvex/lens-shaped mass
•Tx: Neurosurgical decompression
🟠 Subdural Hematoma:
•Concave/crescent-shaped mass
•Focal neurologic symptoms or worsening
•Tx: Serial imaging → Neurosurgical if mass effect
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2️⃣ If Focal Neurological Signs → Non-contrast Head CT
🔵 Intracerebral Hemorrhage:
•Intraparenchymal blood
•Reverse coagulopathy, manage BP, antipyretics
•Monitor for ↑ ICP (Cushing’s triad)
•Tx: Neurosurgical or medical ICP management
🟣 Subarachnoid Hemorrhage:
•Subarachnoid blood
•Lumbar puncture → Xanthochromic CSF
•Tx: Treat secondary headache, ICP control
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3️⃣ If Vertical Eye Movements Are Spared → Non-contrast Head CT
→ CTA/MRA
•🔹 Basilar Artery Stroke
•Tx: Secure airway, manage as stroke
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4️⃣ If CSF Abnormality (↑ WBC, Protein, ↓ Glucose)
→ Consider Meningitis
→ Perform CTV/MRV if venous involvement suspected
•🟤 Venous Sinus Thrombosis:
•Tx: Anticoagulation
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Systemic Lupus Erythematosus (SLE) .
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